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CTCF 蛋白

(CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

recommended

CTCF Protein (AA 1-100) (GST tag) (ABIN1350630)

CTCF 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

CTCF Protein (AA 1-727) (GST tag) (ABIN1350629)

CTCF 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

CTCF Protein (AA 1-154) (His tag) (ABIN7122187)

CTCF 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

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CTCF 蛋白 by Grade

Find CTCF 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CTCF 蛋白 by Origin

Find CTCF 蛋白 for a variety of species such as anti-Human CTCF, anti-Mouse CTCF, anti-Rat CTCF. The species listed below are among those available. Click on a link to go to the corresponding products.

CTCF 蛋白 by Source

Here you will find CTCF 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CTCF 蛋白 by 蛋白类型

Here you can find CTCF 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

CTCF 蛋白 by 应用范围

Find CTCF 蛋白 validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CTCF 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

CTCF Protein (AA 1-100) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1350630

Quantity 10 μg

Datasheet Datasheet

CTCF Protein (AA 1-727) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1350629

Quantity 25 μg

Datasheet Datasheet

CTCF Protein (AA 1-154) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7122187

Quantity 50 μg

Datasheet Datasheet

CTCF Protein (AA 1-727) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3091995

Quantity 1 mg

Datasheet Datasheet

CTCF Protein (AA 1-736) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3135365

Quantity 1 mg

Datasheet Datasheet

CTCF 蛋白

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7319104

Quantity 50 μg

Datasheet Datasheet

CTCF Protein (AA 1-154)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1691993

Quantity 50 μg

Datasheet Datasheet

CTCF Protein (AA 1-737) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1650345

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our CTCF 蛋白

Al-Mahdawi, Sandi, Mouro Pinto, Pook: "Friedreich ataxia patient tissues exhibit increased 5-hydroxymethylcytosine modification and decreased CTCF binding at the FXN locus." in: PLoS ONE, Vol. 8, Issue 9, pp. e74956, (2013) (PubMed).

Shukla, Kavak, Gregory, Imashimizu, Shutinoski, Kashlev, Oberdoerffer, Sandberg, Oberdoerffer: "CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing." in: Nature, Vol. 479, Issue 7371, pp. 74-9, (2011) (PubMed).

Li, Hu, Qiu, Ling, Chen, Wang, Hou, Vu, Hoffman: "CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop." in: Molecular and cellular biology, Vol. 28, Issue 20, pp. 6473-82, (2008) (PubMed).

Aliases for CTCF 蛋白

CCCTC-binding factor (CTCF) 蛋白
CCCTC-binding factor (zinc finger protein) (ctcf) 蛋白
CCCTC-binding factor (ctcf) 蛋白
CCCTC-binding factor (Ctcf) 蛋白
AW108038 蛋白
CTCF 蛋白
im:7152666 蛋白
xctcf 蛋白

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CTCF 蛋白 by Grade

CTCF 蛋白 by Origin

CTCF 蛋白 by Source

CTCF 蛋白 by 蛋白类型

CTCF 蛋白 by 应用范围

Popular CTCF 蛋白

Latest Publications for our CTCF 蛋白

Aliases for CTCF 蛋白

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