C-Type Lectin Domain Family 14, Member A 蛋白 (CLEC14A)

CLEC14A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. 再加上,我们可以发CLEC14A 抗体 (49)CLEC14A 试剂盒 (3)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
CLEC14A 161198 Q86T13
CLEC14A 66864 Q8VCP9
CLEC14A    
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
$5,355.45
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
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人细胞 小鼠 His tag 50 μg Log in to see 14至16个工作日
$382.80
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人细胞 大鼠 Fc Tag 100 μg Log in to see 20至21个工作日
$437.80
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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CLEC14A 蛋白 by Origin and Source

Origin 在表达 标记
Human ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

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Human C-Type Lectin Domain Family 14, Member A (CLEC14A) interaction partners

  1. These findings identify novel protein interactions involving CLEC14A, CD93 (显示 CD93 蛋白) and CD248 (显示 CD248 蛋白) with MMRN2 (显示 MMRN2 蛋白) as targetable components of vessel formation

  2. The CLEC14A-MMRN2 (显示 MMRN2 蛋白) interaction is involved in sprouting angiogenesis. Disrupting this interaction with monoclonal antibodies directed against CLEC14A show anti-angiogenic and anti-tumor effects.

  3. CLEC14A is a matrix component which binds to MMRN2 (显示 MMRN2 蛋白) in the process of endothelial cells transformation in tumor angiogenesis.

  4. clec14a-CTLD may be a key domain in angiogenesis

  5. In this study, they identify and characterize a novel tumor endothelial marker, CLEC14A, which has properties that suggest it is a candidate for tumor vascular targeting and anti-angiogenic approaches.

Mouse (Murine) C-Type Lectin Domain Family 14, Member A (CLEC14A) interaction partners

  1. CLEC14A acts in vascular homeostasis by fine-tuning VEGFR-2 (显示 KDR 蛋白) and VEGFR-3 (显示 FLT4 蛋白) signaling in endothelial cells

  2. clec14a-CTLD may be a key domain in angiogenesis

  3. These findings demonstrate that Clec14a is a novel endothelial cells specific protein that appears to play a role in cell-cell adhesion and angiogenesis.

蛋白简介CLEC14A

蛋白简介

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting.

Gene names and symbols associated with CLEC14A

  • C-type lectin domain containing 14A (CLEC14A)
  • C-type lectin domain family 14, member a (Clec14a)
  • 1200003C23Rik 蛋白
  • AI642649 蛋白
  • C14orf27 蛋白
  • CEG1 蛋白
  • EGFR-5 蛋白

Protein level used designations for CLEC14A

C-type lectin domain family 14 member A , ClECT and EGF-like domain containing protein , epidermal growth factor receptor 5

GENE ID SPECIES
161198 Homo sapiens
66864 Mus musculus
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