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ATE1 encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. 再加上，我们可以发ATE1 蛋白 (4)和数多这个蛋白质的别的产品。
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Human Polyclonal ATE1 Primary Antibody for ELISA, WB - ABIN564818
Hu, Wang, Xia, Varshavsky: The N-end rule pathway is a sensor of heme. in Proceedings of the National Academy of Sciences of the United States of America 2008
Ate1 is downregulated in several types of human cancer samples at the protein level, and that its transcription level inversely correlates with metastatic progression and patient survival.
Data indicate that arginyltransferase 1 (ATE1) function controls Myocardin-related transcription factor A (MRTF-A (显示 MKL1 抗体)) activity.
This study clarifies the role of Ate1/arginylation in stress response.
zipcode-mediated co-targeting of Ate1 and beta-actin (显示 ACTB 抗体) mRNA leads to localized co-translational arginylation of beta-actin (显示 ACTB 抗体) that drives the growth cone migration and neurite outgrowth.
four major isoforms of mouse R-transferase have similar Nt-arginylation specificities in vitro, contrary to the claim about the specificity of some Ate1 isoforms for N-terminal Cys (显示 DNAJC5 抗体)
the crucial role of ATE1 in neural tube development is directly related to proper turn-over of the RGS4 (显示 RGS4 抗体) protein, which participate in the oxygen-sensing mechanism in the cells.
ATE1 knockout cells have impaired purine nucleotide synthesis via selective arginylation of PRPS2 (显示 PRPS2 抗体).
At least 6 isoforms of mouse Ate1 are produced through alternative splicing of Ate1 pre-mRNA. Liat1 has a higher affinity for the isoforms Ate1(1A7A) and Ate1(1B7A).
Loss of ATE1-mediated arginylation leads to impaired platelet myosin phosphorylation, clot (显示 TXNDC17 抗体) retraction, and in vivo thrombosis formation.
ATE1 can mediate both N-terminal and midchain arginylation of Asp (显示 C3 抗体) and Glu (显示 GCG 抗体) in vivo.
Data indicate that arginyl-tRNA-protein transferase ATE1-deficient myocardium and cardiomyocytes showed reduced DNA synthesis and mitotic activity.
This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in two transcript variants encoding distinct isoforms.
, arginyltransferase 1
, arginine-tRNA-protein transferase 1
, arginyl-tRNA--protein transferase 1
, arginyl-tRNA--protein transferase 1-like
, R-transferase 1
, arginine-tRNA--protein transferase 1
, arginyl-tRNA-protein transferase