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The protein encoded by ASB11 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. 再加上，我们可以发ASB11 抗体 (28) 和 ASB11 蛋白 (6)和数多这个蛋白质的别的产品。
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d-Asb11 is a component in the regulation of Delta-Notch (显示 NOTCH1 ELISA试剂盒) signalling, important in fine-tuning the lateral inhibition gradients between DeltaA and Notch (显示 NOTCH1 ELISA试剂盒) through a cell non-autonomous mechanism.[d-Asb11]
We conclude that d-Asb11 is a novel regulator of the neuronal progenitor compartment size by maintaining the neural precursors in the proliferating undifferentiated state possibly through the control of SoxB1 transcription factors.
Zebrafish homozygous for a hypomorphic Asb11 mutation are impaired in muscle progenitor expansion and myotome formation.
Data show that the d-Asb11 cullin box is required for both canonical Notch (显示 NOTCH1 ELISA试剂盒) signaling and proper neurogenesis.
ASB11 is a novel endoplasmic reticulum-associated ubiquitin ligase with the ability to interact and promote the ubiquitination of Ribophorin 1 (显示 RPN1 ELISA试剂盒), an integral protein of the oligosaccharyltransferase (OST (显示 DDOST ELISA试剂盒)) glycosylation complex.
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ankyrin repeat and SOCS box-containing 11
, ankyrin repeat and SOCS box-containing protein 11
, ankyrin repeat and SOCS box containing protein a
, ankyrin repeat and SOCS box protein 9
, Ankyrin repeat and SOCS box protein 11
, ankyrin repeat and SOCS box protein 11
, ankyrin repeat domain-containing SOCS box protein ASB11