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The protein encoded by ANG is an exceedingly potent mediator of new blood vessel formation. 再加上，我们可以发Angiogenin 试剂盒 (88) 和 Angiogenin 蛋白 (35)和数多这个蛋白质的别的产品。
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Association analyses revealed the significant associations (P < 0.05) between the porcine ANG g. 149G>T polymorphism and mean corpuscular volume (MCV), mean corpuscular hemoglobin (显示 HBB 抗体) (MCH (显示 PMCH 抗体)), mean platelet volume (MPV) and platelet-large cell ratio (P-LCR).
Results continue to establish ANG as an oncoprotein and further reveal that ANG contributes to oncogenesis by the activation of MMP2 (显示 MMP2 抗体) through modulation of DNMT3b (显示 DNMT3B 抗体) functions.
(31) RRR (显示 RRS1 抗体)(33) and (50) KRSIK(54) motifs of angiogenin might play a critical role in the regulation of p53 (显示 TP53 抗体)-mediated apoptosis and angiogenesis in cancer cells.
Study shows that plexin-B2 (PLXNB2 (显示 PLXNB2 抗体)) is the functional receptor for ANG in endothelial, cancer, neuronal, and normal hematopoietic and leukemic stem and progenitor cells.
Delivery of the therapeutic human genes VEGF (显示 VEGFA 抗体) and ANG using an adenoviral vector improved functional recovery after traumatic spinal cord injury in a rat model. Immunofluorescent analysis of the post-treatment spinal cord suggested that the positive effect of Ad5 (显示 PSEN2 抗体)-VEGF (显示 VEGFA 抗体)+Ad5 (显示 PSEN2 抗体)-ANG transduction on recovery of locomotor function may be due to the action of glial cells on motor neurons.
Ang down-regulate the expression of Col (显示 HDAC1 抗体)-I, alpha-SMA (显示 SMN1 抗体) and TGF-beta1 (显示 TGFB1 抗体)/Smad2 (显示 SMAD2 抗体)/3 and subsequently inhibits fibroblast-myofibroblast transition.
Ang,Tie1 (显示 TIE1 抗体) and Tie2 (显示 TEK 抗体) play roles in vascular development and pathogenesis of vascular diseases.[review]
Results indicate that angiogenin (ANG) plays a critical role in regulating angiogenesis and follicle survival in xenografted human ovarian tissues.
we found that ANG plays an important role in EMT (显示 ITK 抗体) in squamous cell lung carcinoma and may be a valuable therapeutic target for squamous cell lung carcinoma
There is Lack of association between the Angiogenin (ANG) rs11701 polymorphism and amyotrophic lateral sclerosis risk.
ANG plays a non-cell-autonomous role in regulation of hematopoiesis by simultaneously preserving hematopoietic stem/progenitor cells stemness and promoting myeloid-restricted progenitor cell proliferation.
angiogenin and ILK (显示 ILK 抗体) signaling pathway plays a pivotal role in mediating the inhibitory effects of RI on melanoma cells growth
Our data provide new insights into the paracrine activities of angiogenin in the nervous system, and further highlight the critical role of non-neuronal cells in the pathogenesis of Amyotrophic lateral sclerosis
RNase 4 (显示 RNASE4 抗体) and RNase 5/ang 1 (显示 ANGPT1 抗体) are unique among the RNase A (显示 RNASE1 抗体) ribonuclease genes in that they maintain a complex gene locus that is conserved across species with transcription initiated from tissue-specific dual promoters followed by differential exon splicing.
ANG plays an important role in neurite pathfinding and this has implications for amyotrophic lateral sclerosis.
Angiogenin mRNA was expressed in murine skin in a hair-cycle dependent manner, with maximum levels observed at the late anagen.
All three types of the ANG inhibitor suppress rRNA transcription of the prostate luminal epithelial cells and inhibit AKT (显示 AKT1 抗体)-induced PIN (显示 DYNLL1 抗体), indicating an essential role of ANG in AKT (显示 AKT1 抗体)-mediated cell proliferation and survival.
Murine angiogenin mRNA and protein are upregulated in motoneurons in response to hypoxia, and that Hypoxia-Inducible Factor 1 (显示 HIF1A 抗体) is sufficient and required to upregulate angiogenin expression during hypoxia.
This study is the first to demonstrate that hypoxia upregulates Ang1 (显示 ANGPT1 抗体) expression via HIF2alpha (显示 EPAS1 抗体)-mediated transcriptional activation in pericytes, which plays a key role in angiogenesis.
rAAV-mediated angiogenin gene transfer induces angiogenesis and modifies left ventricular remodeling in rats with myocardial infafrction.
bovine angiogenin is the substance mainly responsible for the inhibitory effect of bovine milk on osteoclast-mediated bone resorption
The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.
, epididymis luminal protein 168
, ribonuclease 5
, angiogenin, ribonuclease A family, member 1
, angiogenin ribonuclease 1