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Anaphase Promoting Complex Subunit 11 抗体

(Anaphase Promoting Complex Subunit 11 (ANAPC11))
Probably catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin- protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin- conjugating E2 enzymes, it catalyzes the formation of protein- ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication. APC11 is required to recruit the ubiquitin- conjugating enzyme E2 to the APC/C.
ANAPC11 抗体 ANAPC11 抗体 ANAPC11 抗体 (ABIN1496631)

ANAPC11 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F5 unconjugated

ANAPC11 抗体  (AA 1-84) ANAPC11 抗体  (AA 1-84) ANAPC11 抗体 (AA 1-84) (ABIN7265580)

ANAPC11 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

ANAPC11 抗体  (AA 1-196) ANAPC11 抗体  (AA 1-196) ANAPC11 抗体 (AA 1-196) (ABIN5542417)

ANAPC11 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 6F1H6 unconjugated

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Popular Anaphase Promoting Complex Subunit 11 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN1496631
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7265580
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (4)
Cat. No. ABIN5542417
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (3)
Cat. No. ABIN565630
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN1496633
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6242773
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN5539618
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
Cat. No. ABIN1714589
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1701087
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1708479
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1712104
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1710290
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1706668
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN4996642
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN4996643
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Anaphase Promoting Complex Subunit 11 抗体

Furukawa, Ohta, Xiong: "Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15758-65, (2002) (PubMed).

Ohta, Michel, Xiong: "Association with cullin partners protects ROC proteins from proteasome-dependent degradation." in: Oncogene, Vol. 18, Issue 48, pp. 6758-66, (2000) (PubMed).

Aliases for Anaphase Promoting Complex Subunit 11 抗体

anaphase promoting complex subunit 11 (ANAPC11) 抗体
anaphase promoting complex subunit 11 L homeolog (anapc11.L) 抗体
anaphase promoting complex subunit 11 (anapc11) 抗体
anaphase promoting complex subunit 11 (Anapc11) 抗体
anaphase-promoting complex/cyclosome 11 (APC11) 抗体
anaphase promoting complex subunit 11 (APC11) 抗体
anaphase-promoting complex subunit Apc11 (apc11) 抗体
anaphase promoting complex subunit 11 (CAALFM_CR10610CA) 抗体
ubiquitin-protein ligase Anaphase Promoting Complex (APC11) 抗体
hypothetical protein (APC11) 抗体
predicted protein (APC11) 抗体
anaphase-promoting complex subunit 11 (LOC9320604) 抗体
anaphase promoting complex subunit 11 (LOC692923) 抗体
APC11 anaphase promoting complex subunit 11 homolog (yeast) (anapc11) 抗体
1110011I19Rik 抗体
anapc11 抗体
anaphase-promoting complex/cyclosome 11 抗体
APC11 抗体
Apc11p 抗体
DDBDRAFT_0187183 抗体
DDBDRAFT_0231277 抗体
DDB_0187183 抗体
DDB_0231277 抗体
F10A16.17 抗体
F10A16_17 抗体
R75218 抗体
RGD1561880 抗体
si:dkey-237i9.4 抗体
zgc:153671 抗体
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