Aminoacylase 1 (ACY1) ELISA试剂盒

ACY1 encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. 再加上,我们可以发Aminoacylase 1 抗体 (114)Aminoacylase 1 蛋白 (16)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
ACY1 95 Q03154
ACY1 109652 Q99JW2
ACY1 300981 Q6AYS7
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适于 Aminoacylase 1 相互作用对的更多 ELISA 试剂盒

Human Aminoacylase 1 (ACY1) interaction partners

  1. with the elevated level in the disease progression of Chronic hepatitis B (CHB), ACY1 autoantibody may be a valuable serum biomarker for discriminating HBVrelated liver cirrhosis from CHB.

  2. Biochemical analysis showed absence of ACY1 enzyme activity in the patient's fibroblasts.

  3. ACY1 acts as a tumor suppressor in hepatocellular carcinoma.

  4. Report serum aminoacylase-1 as a novel biomarker with potential prognostic utility for long-term outcome in renal transplant recipients with delayed graft function.

  5. Case Report: ACY1-deficient patient presenting with autistic features.

  6. We concluded that ACY1 expression in colorectal cancer varies with stage and appears to play a role in cell proliferation and apoptosis

  7. These data suggest that aminoacylase expression is dysregulated in neuroblastoma.

  8. aminoacylase 1 proteins with the mutations p.Arg378Trp, p.Arg378Gln and p.Arg393His were also detected in Western blot analysis

  9. by complementing different active site mutants of human aminoacylase-1, study shows that catalysis occurs at the dimer interface

  10. Genetic deficiency of ACY1 leads to functional ACY1 deficiency and excretion of N-acetylated amino acids.

Pig (Porcine) Aminoacylase 1 (ACY1) interaction partners

  1. Apo (显示 C9orf3 ELISA试剂盒)-aminoacylase followed similar rules as Holo-enzyme, which suggested the zinc ion may play more important roles on activity other than structure

  2. Based on site-directed mutagenesis, homology modeling and substrate docking studies, a revised catalytic mechanism for porcine metalloenzyme aminoacylase 1 has been proposed.

  3. T347S variant of human Acy1 exhibited markedly increased catalytic efficiency against N-benzoylamino acids

Aminoacylase 1 (ACY1) 抗原简介

Antigen Summary

This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.

Gene names and symbols associated with Aminoacylase 1 (ACY1) ELISA试剂盒

  • aminoacylase 1 (ACY1) 抗体
  • aminoacylase 1 (acy1) 抗体
  • aminoacylase 1, gene 1 S homeolog (acy1.1.S) 抗体
  • aminoacylase 1, gene 1 (acy1.1) 抗体
  • aminoacylase 1 (Acy1) 抗体
  • 1110014J22Rik 抗体
  • Acy-1 抗体
  • ACY1 抗体
  • Acy1a 抗体
  • Acy1b 抗体
  • ACY1D 抗体
  • acylase 抗体
  • si:zfos-226g1.1 抗体
  • zgc:55605 抗体
  • zgc:76955 抗体

Protein level used designations for Aminoacylase 1 (ACY1) ELISA试剂盒

aminoacylase-1 , aminoacylase 1 , N-acyl-L-amino-acid amidohydrolase , acylase , ACY IA , ACY IB , ACY-1A , ACY-1B , aminoacylase-1A , aminoacylase-1B , ACY-1 , N-acylamino acid aminohydrolase (Aminoacylase 1)

GENE ID SPECIES
100060631 Equus caballus
393970 Danio rerio
446741 Xenopus laevis
460414 Pan troglodytes
496883 Xenopus (Silurana) tropicalis
100344479 Oryctolagus cuniculus
95 Homo sapiens
109652 Mus musculus
300981 Rattus norvegicus
396930 Sus scrofa
768058 Bos taurus
476602 Canis lupus familiaris
100171519 Pongo abelii
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