ALPL 抗体
(Alkaline Phosphatase, Liver/bone/kidney (ALPL))
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization\; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].
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ALPL 抗体 by Grade
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ALPL 抗体 by 适用
Find ALPL 抗体 for a variety of species such as anti-Human ALPL, anti-Mouse ALPL, anti-Rat ALPL. The species listed below are among those available. Click on a link to go to the corresponding products.
ALPL 抗体 by 抗体来源
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ALPL 抗体 by 克隆形成能力
Find available monoclonal or polyclonal ALPL 抗体. Click on a link to go to the corresponding products.
ALPL 抗体 by 克隆
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Popular ALPL 抗体
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Validations
Cat. No.
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Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
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Cat. No.
ABIN7433150
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC, FACS
Validations
- (2)
- (5)
Cat. No.
ABIN969500
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Cow, Human
Application
IHC, StM
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Cat. No.
ABIN6939448
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC (p)
Validations
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Cat. No.
ABIN3044314
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, FACS, IF
Validations
- (7)
Cat. No.
ABIN3029909
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
Cat. No.
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Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, ICC, IF
Validations
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Cat. No.
ABIN6259900
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC
Validations
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Cat. No.
ABIN1512569
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IHC (p), FACS, EIA
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Cat. No.
ABIN1105293
Quantity
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Datasheet
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Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN730988
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN7433153
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IHC (p)
Validations
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Cat. No.
ABIN540560
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN462352
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Sheep
Application
WB, IHC, IHC (p)
Validations
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- (2)
Cat. No.
ABIN2854870
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Quantity
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Datasheet
Datasheet
Latest Publications for our ALPL 抗体
: "Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration." in: Cell stem cell, Vol. 24, Issue 2, pp. 240-256.e9, (2019) (PubMed).: "Activation of cancer-related and mitogen-activated protein kinase signaling pathways in human mature osteoblasts isolated from patients with type 2 diabetes." in: Bone reports, Vol. 10, pp. 100199, (2019) (PubMed).
: "Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells." in: International journal of molecular sciences, Vol. 20, Issue 5, (2019) (PubMed).
: "Reduced Basal Nitric Oxide Production Induces Precancerous Mammary Lesions via ERBB2 and TGFβ." in: Scientific reports, Vol. 9, Issue 1, pp. 6688, (2019) (PubMed).
: "Osteosarcoma cell-derived exosomes affect tumor microenvironment by specific packaging of microRNAs." in: Carcinogenesis, (2019) (PubMed).
: "Multicolor quantitative confocal imaging cytometry." in: Nature methods, Vol. 15, Issue 1, pp. 39-46, (2018) (PubMed).
: "Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 3, pp. 1086-1096, (2018) (PubMed).
: "Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3β Complex in Hypophosphatasia." in: Theranostics, Vol. 8, Issue 20, pp. 5575-5592, (2018) (PubMed).
: "Development of a micro-tissue-mediated injectable bone tissue engineering strategy for large segmental bone defect treatment." in: Stem cell research & therapy, Vol. 9, Issue 1, pp. 331, (2018) (PubMed).
: "Morphological and functional analyses of skeletal muscles from an immunodeficient animal model of limb-girdle muscular dystrophy type 2E." in: Muscle & nerve, (2018) (PubMed).
Aliases for ALPL 抗体
alkaline phosphatase, liver/bone/kidney L homeolog (alpl.L) 抗体alkaline phosphatase, liver/bone/kidney (ALPL) 抗体
alkaline phosphatase, intestinal, gene 2 (alpi.2) 抗体
alkaline phosphatase, liver/bone/kidney pseudogene (LOC100031702) 抗体
alkaline phosphatase, liver/bone/kidney (Alpl) 抗体
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