anti-Alkaline Phosphatase, Intestinal (ALPI) 抗体

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). 再加上,我们可以发Intestinal Alkaline Phosphatase 试剂盒 (40)Intestinal Alkaline Phosphatase 蛋白 (12)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ALPI 248 P09923
ALPI 24197  
ALPI 76768  
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antibodies-online.cn销售最多的anti-Intestinal Alkaline Phosphatase 抗体

Showing 10 out of 280 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB Western blot analysis of ALPI expression in HepG2 (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
小鼠 非结合性 FACS, ELISA, WB 100 μg Log in to see 2至3个工作日
$430.10
详细
非结合性 IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells treated with Anisomycin 25ug/ml 30', using XIAP (Phospho-Ser87) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using XIAP (Phospho-Ser87) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 IHC, ELISA, WB Western blot analysis of extracts from 293 cells, using XIAP (Ab-87) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using XIAP (Ab-87) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 EIA, WB   0.4 mL Log in to see 12至15个工作日
$518.65
详细
非结合性 IF, WB Western blot analysis of ALPI Antibody (Center) (ABIN388283) in HL60 cell line lysates (35 µg/lane). ALPI (arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Log in to see 10至11个工作日
$324.50
详细
山羊 非结合性 IHC (p) Small intestine, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7至9个工作日
$451.00
详细
非结合性 ELISA, WB Western Blot: Alkaline Phosphatase, Intestinal Antibody [ABIN153475] - Both the antiserum and IgG fractions of anti-Alkaline Phosphatase (Human Intestine) are shown to detect under reducing conditions of SDS-PAGE the 60,000 dalton enzyme in cellular extracts. Approximately 10 ug of total protein is loaded per lane. A 1:5,000 dilution of the primary antibody is used followed by detection using HRP Goat-a-Rabbit IgG [H&L] diluted 1:4,000 and color development using 4-CN substrate until sufficient color develops. 0.2 mL Log in to see 7至9个工作日
$301.88
详细
非结合性 ELISA, IHC (p) Immunochemical staining of human ALPI in human esophagus with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).Positive staining was localized to epithelium. Immunochemical staining of human ALPI in human kidney with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).Positive staining was localized to nephric tubule. 100 μg Log in to see 20至21个工作日
$218.90
详细
非结合性 EIA, IF, IHC (p), IP, WB 50 μL Log in to see 6至8个工作日
$390.50
详细

通过反应活性、应用领域、克隆类型和共轭标记 ALPI 抗体

特性 应用范围 宿主 克隆类型 标记
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Rat (Rattus) ,


Mouse (Murine) ,


引用最多的anti-Intestinal Alkaline Phosphatase 抗体

  1. Human Polyclonal Intestinal Alkaline Phosphatase Primary Antibody for ELISA, WB - ABIN153475 : Wilson, Byun, Popova, Murray, LItalien, Sowa, Arango, Velcich, Augenlicht, Mariadason: Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal Intestinal Alkaline Phosphatase Primary Antibody for FACS, ELISA - ABIN1724814 : Molnár, Vannay, Sziksz, Bánki, Gy?rffy, Arató, Dezs?fi, Veres: Decreased mucosal expression of intestinal alkaline phosphatase in children with coeliac disease. in Virchows Archiv : an international journal of pathology 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal Intestinal Alkaline Phosphatase Primary Antibody for FACS, ELISA - ABIN1724815 : Molnár, Vannay, Szebeni, Bánki, Sziksz, Cseh, Gy?rffy, Lakatos, Papp, Arató, Veres: Intestinal alkaline phosphatase in the colonic mucosa of children with inflammatory bowel disease. in World journal of gastroenterology : WJG 2012 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal Intestinal Alkaline Phosphatase Primary Antibody for ELISA, WB - ABIN559857 : Lechner, Reichel, Moenning, Reichel, Fricker: Development of a fluorescence-based assay for drug interactions with human Multidrug Resistance Related Protein (MRP2; ABCC2) in MDCKII-MRP2 membrane vesicles. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2010 (PubMed)

  5. Human Polyclonal Intestinal Alkaline Phosphatase Primary Antibody for IF, WB - ABIN388283 : Hendarto, Prabowo, Moeloek, Soetjipto: Growth differentiation factor 9 concentration in the follicular fluid of infertile women with endometriosis. in Fertility and sterility 2010 (PubMed)

更多抗Intestinal Alkaline Phosphatase的相互作用对抗体

Human Alkaline Phosphatase, Intestinal (ALPI) interaction partners

  1. Expressions of human intestinal alkaline phosphatase and sucrase-isomaltase, which are intestinal differentiation markers, were highly enhanced in Caco-2 cells by menaquinone-4.

  2. Data indicate alkaline phosphatase (AP) as the primary soluble ectonucleotidase in infants undergoing cardiopulmonary bypass and show decreased capacity to clear AMP (显示 APRT 抗体) when AP activity decreases post-bypass.

  3. Intestinal alkaline phosphatase is a major regulator of gut (显示 GUSB 抗体) mucosal permeability and appears to work at least partly through improving tight junction protein (显示 OCLN 抗体) levels and localization.

  4. A High Level of Intestinal Alkaline Phosphatase Is Protective Against Type 2 Diabetes Mellitus Irrespective of Obesity

  5. Review of the role of intestinal alkaline phosphatase in inflammatory diseases. Loss of IAP expression or function is associated with increased intestinal inflammation, dysbiosis, bacterial translocation and subsequently systemic inflammation.

  6. The expression of ALPi and MUC5AC in cocultures of Caco-2 and HT29 cells developed for permeability studies is reported.

  7. Data indicate that histone deacetylase (显示 HDAC1 抗体) inhibitors (HDACi) induce intestinal alkaline phosphatase (ALPi) in a subset of colon cancer cell lines in a Kruppel-like factor 5 (KLF5 (显示 KLF5 抗体))-dependent manner.

  8. Report lowered intestinal alkaline phosphatase in the colonic mucosa of children with inflammatory bowel disease.

  9. we are the first to demonstrate the alteration of protein expression of iAP in the duodenal mucosa of children with newly diagnosed coeliac disease

  10. Mechanism of IAP action appears to be through dephosphorylation of specific bacterial components, including LPS (显示 IRF6 抗体), CpG DNA, and flagellin (显示 FliC 抗体), and not on live bacteria. IAP likely targets these bacterially derived molecules as gut (显示 GUSB 抗体) mucosal defense factor.

Mouse (Murine) Alkaline Phosphatase, Intestinal (ALPI) interaction partners

  1. Intestinal alkaline phosphatase is a major regulator of gut (显示 GUSB 抗体) mucosal permeability and appears to work at least partly through improving tight junction protein (显示 OCLN 抗体) levels and localization.

  2. Authors found that Akp3(-/-) mice acquired lipopolysaccharide tolerance during postweaning development, suggesting that Akp3 plays an important role in immune education.

  3. Intestinal alkaline phosphatase prevents metabolic syndrome in mice.

  4. It is concluded that CD36 (显示 CD36 抗体) exists in its phosphorylated and dephosphorylated states in mouse enterocytes and that pCD36 is a substrate of global intestinal alkaline phosphatase (gIAP).

  5. These data suggest that IAP is a local immunomodulating factor, perhaps regulating LPS-toll-like receptor 4 (显示 TLR4 抗体) (TLR4 (显示 TLR4 抗体)) interaction between commensal microflora and intestinal epithelium.

  6. Results suggest that intestinal alkaline phosphatase participates in a rate-limiting step regulating fat absorption.

  7. forced high-fat chow induced an 18% greater body weight gain, hepatic steatosis, and visceral fat accumulation in female Akp3(-/-) mice but not in female wild-type controls. there is 2X increase of lipid absorption in Akp3(-/-) male mice.

  8. Intestinal alkaline phosphatase activity may have a role in mediating the accelerated fatty acid intake observed in Akp3 knockout mice fed a high-fat diet.

  9. Suggest role for lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration.

Cow (Bovine) Alkaline Phosphatase, Intestinal (ALPI) interaction partners

  1. Mechanism of IAP action appears to be through dephosphorylation of specific bacterial components, including LPS (显示 IRF6 抗体), CpG DNA, and flagellin (显示 FliC 抗体), and not on live bacteria. IAP likely targets these bacterially derived molecules as gut (显示 GUSB 抗体) mucosal defense factor.

  2. Secondary structure of CIP after reaction with Co2+ in different conditions.

Intestinal Alkaline Phosphatase (ALPI) 抗原简介

蛋白简介

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is upregulated during small intestinal epithelial cell differentiation.

Gene names and symbols associated with ALPI

  • alkaline phosphatase, intestinal (ALPI) 抗体
  • alkaline phosphatase, intestinal (Alpi) 抗体
  • alkaline phosphatase, intestinal, tandem duplicate 1 (alpi.1) 抗体
  • intestinal-type alkaline phosphatase (LOC100724954) 抗体
  • 2010001C14Rik 抗体
  • Akp6 抗体
  • Alp1 抗体
  • Alpi 抗体
  • gIAP 抗体
  • IAP 抗体
  • im:7149588 抗体
  • S51097 抗体
  • si:ch211-262h13.1 抗体
  • wu:fa95f04 抗体
  • zgc:110794 抗体

Protein level used designations for ALPI

Kasahara isozyme , alkaline phosphomonoesterase , glycerophosphatase , intestinal alkaline phosphatase , intestinal-type alkaline phosphatase , Alkaline phosphatase 1, intestinal, defined by SSR , IAP-1 , IAP-I , intestinal alkaline phosphatase 1 , intestinal alkaline phosphatase I IAP-I , intestinal-type alkaline phosphatase 1 , alkaline phosphatase 6 , intestinal alkaline phosphatase V , alkaline phosphatase, intestinal.1 , iap , alkaline phosphatase, intestinal , intestinal-type alkaline phosphatase-like

GENE ID SPECIES
248 Homo sapiens
24197 Rattus norvegicus
76768 Mus musculus
280993 Bos taurus
424936 Gallus gallus
541539 Danio rerio
100399082 Callithrix jacchus
100437471 Pongo abelii
100465399 Ailuropoda melanoleuca
403736 Canis lupus familiaris
100724954 Cavia porcellus
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