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ADD3 蛋白

(Adducin 3 (Gamma) (ADD3))
Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known. [provided by RefSeq, Jul 2008].
ADD3 Protein (AA 462-560) (GST tag) ADD3 Protein (AA 462-560) (GST tag) ADD3 Protein (AA 462-560) (GST tag) (ABIN1305971)

ADD3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

ADD3 Protein (AA 2-706) (His tag) ADD3 Protein (AA 2-706) (His tag) ADD3 Protein (AA 2-706) (His tag) (ABIN3088692)

Crystallography grade ADD3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

ADD3 Protein (AA 2-706) (His tag) ADD3 Protein (AA 2-706) (His tag) ADD3 Protein (AA 2-706) (His tag) (ABIN3130515)

Crystallography grade ADD3 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

ADD3 蛋白 by Grade

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ADD3 蛋白 by Origin

Find ADD3 蛋白 for a variety of species such as anti-Human ADD3, anti-Mouse ADD3, anti-Rat ADD3. The species listed below are among those available. Click on a link to go to the corresponding products.

ADD3 蛋白 by Source

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ADD3 蛋白 by 蛋白类型

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ADD3 蛋白 by 应用范围

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Popular ADD3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305971
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088692
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3130515
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421470
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2721671
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2721672
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1634380
Quantity 1 mg
Datasheet Datasheet

Aliases for ADD3 蛋白

adducin 3 (gamma) (ADD3) 蛋白
adducin 3 (add3) 蛋白
adducin 3 (ADD3) 蛋白
adducin 3 L homeolog (add3.L) 蛋白
adducin 3 (gamma) (Add3) 蛋白
adducin 3 (Add3) 蛋白
add3 蛋白
ADD3 蛋白
ADDL 蛋白
AI463285 蛋白
DKFZp459E0630 蛋白
gamma-adducin 蛋白
MGC89418 蛋白
R75380 蛋白
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