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Plays a role in autophagy. 再加上，我们可以发ATG9A 抗体 (123) 和 ATG9A 蛋白 (5)和数多这个蛋白质的别的产品。
phosphorylation of mATG9 at Tyr8 by Src (显示 SRC ELISA试剂盒) and at Ser14 by ULK1 (显示 ULK1 ELISA试剂盒) functionally cooperate to promote interactions between mATG9 and the AP1 (显示 FOSB ELISA试剂盒)/2 complex.
In these Rab1B (显示 RAB1B ELISA试剂盒)-depleted cells, ATG9A accumulated in intermediate membrane structures at autophagosome formation sites. These results indicate that Rab1B (显示 RAB1B ELISA试剂盒) is involved in regulating the proper development of autophagosomes.
we focus on the contributions of the plasma membrane to autophagosome biogenesis governed by ATG16L1 (显示 ATG16L1 ELISA试剂盒) and ATG9A trafficking, and summarize the physiological and pathological implications of this macroautophagy route, from development and stem cell fate to neurodegeneration and cancer.
the C-terminal glycine of human ATG9A is required for its transport from the endoplasmic reticulum to the Golgi apparatus
these findings provide new insights into the intracellular pathways followed by ATG9A to reach different subcellular compartments, and into the intramolecular determinants that drive the sorting of this protein.
Results suggest that quinocetone stimulates the MRLC-mediated mAtg9 trafficking, which is critical for autophagosome formation, via the ATF6 (显示 ATF6 ELISA试剂盒) upregulated expression of DAPK1 (显示 DAPK1 ELISA试剂盒).
This study highlights the transcriptional inactivation mechanisms of ATG2B, ATG4D (显示 ATG4D ELISA试剂盒), ATG9A and ATG9B (显示 ATG9B ELISA试剂盒) promoter methylation status and the possible origin of autophagy signal pathway repression in invasive ductal carcinomas.
Importantly, TBC1D14 (显示 TBC1D14 ELISA试剂盒) and TRAPPIII regulate ATG9 trafficking independently of ULK1 (显示 ULK1 ELISA试剂盒).
These two steps are essential for the maturation of small single-membrane autophagic precursors containing ATG16L1 (显示 ATG16L1 ELISA试剂盒) and mATG9 proteins into double-membrane autophagosomes
D620N mutation in VPS35 (显示 vps35 ELISA试剂盒) restricts WASH complex recruitment to endosomes, inhibiting autophagy. The autophagy defects can be explained, at least in part, by abnormal trafficking of the autophagy protein ATG9A.
the trafficking of Atg9A through the recycling endosomes is an essential step for autophagosome formation.
Atg9a(-/-) fetal mice from pregnant dams heterozygous for both knockout alleles of Atg9a and p57(Kip2 (显示 CDKN1C ELISA试剂盒)) are more susceptible to hypertensive stress than fetuses with intact autophagic machinery.
Atg9a expression is required for neural stem cell differentiation.
Knockdown of Atg9a resulted in enhanced stimulator of IFN genes-mediated production of IFN-beta (显示 IFNB1 ELISA试剂盒) by aged macrophages
Both AMPK (显示 PRKAA1 ELISA试剂盒) and ULK1 (显示 ULK1 ELISA试剂盒) regulate localization of a critical component of the phagophore, ATG9.
In the initial steps of Parkin (显示 PARK2 ELISA试剂盒)-mediated mitophagy, the structures containing the ULK1 (显示 ULK1 ELISA试剂盒) complex and Atg9A are independently recruited to depolarized mitochondria.
STING co-localizes with the autophagy proteins, microtubule-associated protein (显示 SPAG5 ELISA试剂盒) 1 light chain 3 (LC3 (显示 MAP1LC3A ELISA试剂盒)) and autophagy-related gene 9a (Atg9a), after dsDNA stimulation.
Atg9Ap may be involved in autophagosome formation in the ER and axon terminals of neurons, the TGN (显示 TG ELISA试剂盒), and lysosomes/late endosomes.
Plays a role in autophagy. Cycles between a juxta- nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and FAM48A (By similarity).
ATG9 autophagy related 9 homolog A
, autophagy protein 9
, ATG9 autophagy related 9 homolog A (S. cerevisiae)
, autophagy-related protein 9A
, Autophagy-related protein 9A
, APG9-like 1
, APG9 autophagy 9-like 1
, autophagy 9-like 1 protein
, autophagy-related 9-like 1
, autophagy-related 9A