APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) ELISA试剂盒

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. 再加上,我们可以发APEX2 抗体 (59)APEX2 蛋白 (3)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
APEX2 27301 Q9UBZ4
APEX2 77622 Q68G58
大鼠 APEX2 APEX2 317628  
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< 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Log in to see 11至18个工作日
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适于 APEX2 相互作用对的更多 ELISA 试剂盒

Human APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) interaction partners

  1. Single-Strand Break End Resection in Genome Integrity: Mechanism and Regulation by APE2.

  2. Determinants in nuclease specificity of Ape1 and Ape2, human homologues of Escherichia coli exonuclease III

  3. Ape2 exhibits strong 3'-5' exonuclease and 3'-phosphodiesterase activities and has only a very weak AP-endonuclease activity.

  4. Ape2 may be involved in repair of oxidative DNA damage and PCNA-dependent repair synthesis.

  5. Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.

Xenopus laevis APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) interaction partners

  1. APE2 associates with Chk1; a serine residue (S86) in the Chk1-binding motif of APE2 is essential for Chk1 phosphorylation, indicating a Claspin-like but distinct role for APE2 in ATR-Chk1 signaling.

APEX2 抗原简介

Antigen Summary

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with APEX2

  • apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2) 抗体
  • apurinic/apyrimidinic endodeoxyribonuclease 2 (apex2) 抗体
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (apex2) 抗体
  • apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog (apex2.L) 抗体
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2) 抗体
  • apurinic/apyrimidinic endonuclease 2 (Apex2) 抗体
  • apurinic/apyrimidinic endodeoxyribonuclease 2 (Apex2) 抗体
  • ape2 抗体
  • apexl2 抗体
  • C430040P13Rik 抗体
  • xth2 抗体
  • zgc:55889 抗体

Protein level used designations for APEX2

AP endonuclease 2 , AP endonuclease XTH2 , DNA-(apurinic or apyrimidinic site) lyase 2 , apurinic/apyrimidinic endonuclease-like 2 , APEX nuclease 2 , apurinic-apyrimidinic endonuclease 2 , APEX nuclease (apurinic/apyrimidinic endonuclease) 2 , DNA-(apurinic or apyrimidinic site) lyase 2-like

GENE ID SPECIES
27301 Homo sapiens
448512 Xenopus (Silurana) tropicalis
393115 Danio rerio
446614 Xenopus laevis
491499 Canis lupus familiaris
511790 Bos taurus
702084 Macaca mulatta
100410557 Callithrix jacchus
100434759 Pongo abelii
77622 Mus musculus
317628 Rattus norvegicus
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