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ADAMTS1 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. 再加上，我们可以发ADAMTS1 抗体 (137) 和 ADAMTS1 蛋白 (14)和数多这个蛋白质的别的产品。
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Human ADAMTS1 ELISA Kit for Sandwich ELISA - ABIN415114
Tyan, Hsu, Peng, Chen, Kuo, Lee, Shew, Chang, Juan, Lee: Breast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic change. in PLoS ONE 2012
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Expression and induction of ADAMTS-1 through receptor-mediated action of progesterone in cumulus cells is one of essential requirements for gonadotropin-regulated cumulus expansion of porcine cumulus-oocyte complexes.
study indicates that disintegrin and metalloproteinase with thrombospondin motifs 1(ADAMTS1) participates in bovine endometrial remodeling
Data indicate that ADAMTS1 promoter activity and mRNA expression were increased by forskolin and human chorionic gonadotropin.
we identified Adamts1 as the modulator of a potent pathway that converts changes in diet into a cellular signal in adipose tissue that controls APC (显示 APC ELISA试剂盒) activity in vivo
ADAMTS 1 may be necessary during the decidualization and implantation stages of early normal pregnancy.
Significant differences in gene expression profiles were observed between patients with post-kidney transplant bladder tumors and those with conventional bladder tumors. ADAMTS1 expression was significantly lower in first group than in the second.
Our study demonstrated that altered levels of ADAMTS-1 and aggrecan (显示 ACAN ELISA试剂盒) may have a partial role in the etiopathogenesis of Polycystic ovary syndrome (PCOS), and ADAMTS-1 could be a predictive marker for implantation success in PCOS patients.
Adamts1 acts as an extracellular matrix 'modifier', with miR (显示 MLXIP ELISA试剂盒)-181d-induced downregulation, that regulates adipocyte lineage commitment and obesity.
This study showed that ADAMTS1, 8, and 18 are highly expressed in GC and its nodal metastases, suggesting important roles of these proteases in carcinogenesis and lymphatic metastasis. The findings from the present study indicate that these proteases may be promising candidates for novel and alternative treatments in GC (gastric cancer)
Taken together, our findings suggested that miR (显示 MLXIP ELISA试剂盒)-362-3p inhibits the proliferation and migration of VSMCs by directly targeting ADAMTS1, which might provide novel insight into the molecular mechanisms underlying the action of miR (显示 MLXIP ELISA试剂盒)-362-3p in atherosclerosis.
ADAMTS1 has diverse roles in angiogenesis, tumor microenvironment and lymphangiogenesis.
Patients with Marfan syndrome showed elevated NOS2 and decreased ADAMTS1 protein levels in the aorta.
Data indicate that serum versican (显示 Vcan ELISA试剂盒) levels were significantly decreased in polycystic ovary syndrome (PCOS) patients, and that serum ADAMTS-1 (a disintegrin and metalloproteinase with thrombospondin motif-1) and versican (显示 Vcan ELISA试剂盒) levels were significantly and positively correlated with each other.
The developmental arrest of early secondary follicles following furin (显示 FURIN ELISA试剂盒) disruption might be rooted in the loss of the mature form of ADAMTS1 and compromised proliferation of granulosa cells in mutant mice.
Data show that NOTCH1 (显示 NOTCH1 ELISA试剂盒) is a target of ADAMTS1 metalloproteinase activity, which reduces Notch (显示 NOTCH1 ELISA试剂盒) signaling, leading to increased satellite cell activation.
Reduced tumors in ADAMTS1 knockout mice displayed a paradoxical increase in vascular density and vascular-related genes; a detailed characterization revealed an impaired vasculature, along with a minor infiltration of macrophages. melanoma xenografts showed a relevant induction of its expression in stroma compartments.
Genetic haploinsufficiency of Adamts1 in mice causes thoracic aortic aneurysms and dissections similar to Marfan syndrome.
An ADAMTS1 blocking antibody suppressed the SPARC (显示 SPARC ELISA试剂盒)-induced collagen I secretion, indicating that SPARC (显示 SPARC ELISA试剂盒) promoted collagen production directly through ADAMTS1 interaction. In conclusion, ADAMTS1 is an important mediator of SPARC (显示 SPARC ELISA试剂盒)-regulated cardiac aging.
increased expression of ADAMTS1 protein in macrophages and neutrophils that infiltrated aortic tissues may promote the progression of acute aortic dissection
The resilience of casp1 (显示 CASP1 ELISA试剂盒)(-/-) mice to SIRS lethality is associated with a lower inflammatory response, loss of hippocampal gene coexpression patterns, and increased hippocampal Adamts1 gene expression.
Adamts-1 upregulation by inducers of pathological vascular remodeling is mediated by specific signal transduction pathways involving NFAT (显示 NFATC1 ELISA试剂盒) or C/EBPbeta (显示 CEBPB ELISA试剂盒) transcription factors.
Western blot analyses indicated that aggrecanase (显示 ADAMTS4 ELISA试剂盒)-generated proteoglycan (显示 Vcan ELISA试剂盒) fragments are produced after SCI.
ADAMTS1 negatively modulates FGF signaling in the Xenopus embryo.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
metalloproteinase with thrombospondin-like motifs-1
, ADAM metallopeptidase with thrombospondin type 1 motif, 1
, A disintegrin and metalloproteinase with thrombospondin motifs 1
, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1
, ADAM-TS 1
, a disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS-1)
, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
, a disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1
, human metalloproteinase with thrombospondin type 1 motifs
, ADAM metallopeptidase with thrombospondin type 1 motif 1 L homeolog