1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2) ELISA试剂盒

AGPAT2 encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. 再加上,我们可以发AGPAT2 抗体 (47)AGPAT2 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
AGPAT2 10555 O15120
AGPAT2 311821  
AGPAT2 67512 Q8K3K7
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适于 AGPAT2 相互作用对的更多 ELISA 试剂盒

Human 1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2) interaction partners

  1. Data show that missense mutation c.299G>A changes serine in the acyltransferase NHX4D motif of AGPAT2, and intronic c.493-1G>C mutation destroy a splicing site that leads to exon 4 skipping and deletion of whole AGPAT2 substrate binding domain.

  2. the ability of LPAAT-beta to regulate mTOR (显示 FRAP1 ELISA试剂盒) function

  3. miR-24 may play an important role in inhibiting osteosarcoma growth through suppression of LPAATbeta.

  4. Data suggest that AGPAT2 regulates adipogenesis through modulation of lipid metabolism/signal transduction, altering normal activation of phosphatidylinositol 3-kinase (PI3K (显示 PIK3CA ELISA试剂盒))/protooncogene c-Akt (显示 AKT1 ELISA试剂盒) and PPARgamma (显示 PPARG ELISA试剂盒) signaling in early stage of adipogenesis.

  5. the role of AGPAT1 (显示 AGPAT1 ELISA试剂盒) or AGPAT2 in liver lipogenesis is minimal and that accumulation of liver fat is primarily a consequence of insulin (显示 INS ELISA试剂盒) resistance

  6. lpaat beta gene overexpression exists in both AML (显示 RUNX1 ELISA试剂盒) and CML (显示 BCR ELISA试剂盒) patients. lpaat beta produced by AML (显示 RUNX1 ELISA试剂盒) cells probably plays an important role in abnormal proliferation and drug-resistance of AML (显示 RUNX1 ELISA试剂盒) cells.

  7. Lysophosphatidic acid acyltransferase beta (LPAATbeta) promotes the tumor growth of human osteosarcoma

  8. AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34.

  9. Congenital lipodystrophy patients with Seipin (显示 BSCL2 ELISA试剂盒) mutations have a more severe lack of body fat, which affects both metabolically active and mechanical adipose tissue, compared with patients with mutations in the AGPAT2 gene.

  10. mutations in AGPAT2 and Gng3lg (显示 BSCL2 ELISA试剂盒) are approximately equally represented in congenital generalized lipodystrophy

Cow (Bovine) 1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2) interaction partners

  1. Data indicate that the longissimus dorsi muscle (LM) of steers showed higher G0/G1 switch gene 2 (G0S2) and comparative gene identification-58 (CGI-58) mRNA expression levels than the LM of bulls.

Mouse (Murine) 1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2) interaction partners

  1. Adipogenically induced Agpat2(-/-) preadipocytes had fewer lipid-loaded cells and lower levels of adipocyte markers than wild type preadipocytes.

  2. Leptin (显示 LEP ELISA试剂盒) ameliorates insulin (显示 INS ELISA试剂盒) resistance and hepatic steatosis in Agpat2-/- lipodystrophic mice independent of hepatocyte leptin (显示 LEP ELISA试剂盒) receptors

  3. The lack of normal insulin (显示 INS ELISA试剂盒) signaling in Agpat2(-/-) livers allows unrestricted phosphatidic acid-induced gluconeogenesis.

  4. Data suggest that Agpat2 regulates adipogenesis through modulation of lipid metabolism/signal transduction, altering normal activation of phosphatidylinositol 3-kinase (PI3K)/protooncogene c-Akt (显示 AKT1 ELISA试剂盒) and PPARgamma (显示 PPARG ELISA试剂盒) signaling in early stage of adipogenesis.

  5. the role of AGPAT1 (显示 AGPAT1 ELISA试剂盒) or AGPAT2 in liver lipogenesis is minimal and that accumulation of liver fat is primarily a consequence of insulin (显示 INS ELISA试剂盒) resistance

  6. Loss of adipocytes by necrosis and apoptosis in Agpat2 null mice

  7. impaired AGPAT2 activity affects availability of phosphatidic acid (PA) for triacylglycerol synthesis but not overall PA synthesis nor utilization of PA for phospholipid synthesis

  8. The alternative monoacylglycerol pathway for triglyceride biosynthesis is activated in the absence of 1-acylglycerol-3-phosphate O-acyltransferase 2.

AGPAT2 抗原简介

Antigen Summary

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with AGPAT2

  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2) 抗体
  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (agpat2) 抗体
  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (agpat2) 抗体
  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (Agpat2) 抗体
  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2) 抗体
  • 1-AGPAT2 抗体
  • 2510002J07Rik 抗体
  • AGPAT2 抗体
  • AV000834 抗体
  • BSCL 抗体
  • BSCL1 抗体
  • LPAAB 抗体
  • LPAAT-beta 抗体
  • zgc:153984 抗体

Protein level used designations for AGPAT2

1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) , 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha , 1-AGP acyltransferase 2 , 1-AGPAT 2 , 1-acyl-sn-glycerol-3-phosphate acyltransferase beta , lysophosphatidic acid acyltransferase beta , lysophosphatidic acid acyltransferase-beta , lysophosphatidic acid acyltransferase, beta

GENE ID SPECIES
709753 Macaca mulatta
748669 Pan troglodytes
772114 Gallus gallus
777624 Danio rerio
100170486 Xenopus (Silurana) tropicalis
10555 Homo sapiens
311821 Rattus norvegicus
491249 Canis lupus familiaris
100170768 Sus scrofa
512112 Bos taurus
67512 Mus musculus
101114511 Ovis aries
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