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WTIP 蛋白

(Wilms Tumor 1 Interacting Protein (WTIP))
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. May monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1- dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype.
WTIP Protein (AA 1-430) (His tag) WTIP Protein (AA 1-430) (His tag) WTIP Protein (AA 1-430) (His tag) (ABIN3096372)

Crystallography grade WTIP 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA

WTIP Protein (Myc-DYKDDDDK Tag) WTIP Protein (Myc-DYKDDDDK Tag) WTIP Protein (Myc-DYKDDDDK Tag) (ABIN2735591)

WTIP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

WTIP 蛋白 by Grade

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WTIP 蛋白 by Origin

Find WTIP 蛋白 for a variety of species such as anti-Human WTIP. The species listed below are among those available. Click on a link to go to the corresponding products.

WTIP 蛋白 by Source

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WTIP 蛋白 by 蛋白类型

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WTIP 蛋白 by 应用范围

Find WTIP 蛋白 validated for a specific application such as AbP, ELISA, SDS, STD. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular WTIP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3096372
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2735591
Quantity 20 μg
Datasheet Datasheet

Aliases for WTIP 蛋白

WT1 interacting protein (Wtip) 蛋白
WT1 interacting protein (WTIP) 蛋白
WT1 interacting protein (wtip) 蛋白
Wilms tumor 1 interacting protein (WTIP) 蛋白
WT1 interacting protein L homeolog (wtip.L) 蛋白
WT1-interacting protein (Wtip) 蛋白
RGD1306411 蛋白
si:ch211-79l17.3 蛋白
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