anti-TCF4 (TCF4) 抗体产品概述

Full name:
anti-Transcription Factor 4 抗体 (TCF4)
在www.antibodies-online.cn可供86 Transcription Factor 4 (TCF4) 抗体的20不同的供货商。 再加上,我们可以发TCF4 试剂盒 (10)TCF4 蛋白 (9)和数多这个蛋白质的别的产品。 总共111 TCF4产品已列进来了。
别名:
5730422P05Rik, ASP-I2, bHLHb19, E2-2, e2-A, E2.2, GE2, ITF-2, ITF-2b, ITF2, ME2, MITF-2A, MITF-2B, mTcf-4B, mTcf-4E, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, Tcf-4, Tcf4, TCF4B, TCF4E, TCF7L2, TFE, XE2, Xtcf-4, Xtcf4

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引用最多的anti-TCF4 抗体

  1. Human Monoclonal TCF4 Primary Antibody for IHC (p), IP - ABIN264393 : Barker, Huls, Korinek, Clevers: Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium. in The American journal of pathology 1999 (PubMed)
    Show all 5 references for 264393

  2. Human Monoclonal TCF4 Primary Antibody for IF, ELISA - ABIN520754 : Tanaka, Itoh, Nishiyama, Takezawa, Kurihara, Itoh, Kato: Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis. in Blood 2010 (PubMed)
    Show all 3 references for 520754

  3. Human Monoclonal TCF4 Primary Antibody for EMSA, IHC (p) - ABIN264394 : Denys, Jadidizadeh, Amini Nik, Van Dam, Aerts, Alman, Cassiman, Tejpar: Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors. in Oncogene 2004 (PubMed)
    Show all 2 references for 264394

  4. Human Polyclonal TCF4 Primary Antibody for IF, IP - ABIN318967 : Valenta, Lukas, Doubravska, Fafilek, Korinek: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. in The EMBO journal 2006 (PubMed)

  5. Human Monoclonal TCF4 Primary Antibody for IF, WB - ABIN393964 : Eichhoff, Weeraratna, Zipser, Denat, Widmer, Xu, Kriegl, Kirchner, Larue, Dummer, Hoek: Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching. in Pigment cell & melanoma research 2011 (PubMed)

  6. Guinea Pig Polyclonal TCF4 Primary Antibody for WB - ABIN2792580 : Raurell, Castaño, Francí, García de Herreros, Duñach: Presenilin-1 interacts with plakoglobin and enhances plakoglobin-Tcf-4 association. Implications for the regulation of beta-catenin/Tcf-4-dependent transcription. in The Journal of biological chemistry 2006 (PubMed)

  7. Guinea Pig Polyclonal TCF4 Primary Antibody for WB - ABIN2792579 : Lu, Sheng, Mo, Li, Wu, Shen: A negative regulatory element-dependent inhibitory role of ITF2B on IL-2 receptor alpha gene. in Biochemical and biophysical research communications 2005 (PubMed)

更多抗TCF4的相互作用对抗体

Zebrafish Transcription Factor 4 (TCF4) interaction partners

  1. GRG5/AES (显示 AES 抗体) interacts with TCF4 (显示 TCF7L2 抗体) and represses Wnt (显示 WNT2 抗体)-mediated transcription both in human cells and zebrafish embryos.

Xenopus laevis Transcription Factor 4 (TCF4) interaction partners

  1. Data indicte that Tcf-1 (显示 HNF1A 抗体) and Lef-1 (显示 LEF1 抗体) exhibit a function in the axis induction assay, which is lacking in Tcf-3 (显示 TCF3 抗体) and -4.

  2. Tcf4 (显示 TCF7L2 抗体) transcription factor cooperates in patterning the Xenopus brain.

Human Transcription Factor 4 (TCF4) interaction partners

  1. We found that the genotype "AG" of rs9320010 and "GA" of rs7235757 decreased SCZ risk. In the genetic model analysis, we also observed that the allele "A" of rs9320010 and "G" of rs7235757 were inversely related with the risk of SCZ in the dominant model. Our study indicated that rs9320010, rs7235757, and rs1452787 were prominently associated with SCZ.

  2. Our work suggests that DM1 (显示 DMPK 抗体) patients are at risk for Fuchs' endothelial corneal dystrophy (FECD (显示 COL8a2 抗体)). DMPK (显示 DMPK 抗体) mutations contribute to the genetic burden of FECD (显示 COL8a2 抗体) but are uncommon. We establish a connection between two repeat expansion disorders converging upon RNA-MBNL1 (显示 MBNL1 抗体) foci and FECD (显示 COL8a2 抗体).

  3. the variation of the TCF7L2 (显示 TCF7L2 抗体) gene in three Amerindian populations

  4. These data define the mechanism responsible for the repressive effects of nitric oxide (NO) on the transcriptional activity of beta-catenin (显示 CTNNB1 抗体) and link eNOS (显示 NOS3 抗体)-derived NO to the modulation by VEGF (显示 VEGFA 抗体) of Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体)-induced endothelial cell proliferation.

  5. we show that TopoIIalpha forms protein-protein interactions with beta-catentin and TCF4 and interacts with Wnt (显示 WNT2 抗体) response elements (WREs) and promoters of direct target genes of TCF (显示 HNF4A 抗体) transcription, including: MYC (显示 MYC 抗体), vimentin (显示 VIM 抗体), AXIN2 (显示 AXIN2 抗体) and LEF1 (显示 LEF1 抗体)

  6. novel TCF7L2 (显示 TCF7L2 抗体) type 2 diabetes SNP identified from fine mapping in African American women

  7. GWAS identified two known loci (TCF7L2 (显示 TCF7L2 抗体) and KCNQ1 (显示 KCNQ1 抗体)) reaching genome-wide significance levels in Hispanic type 2 diabetes patients.

  8. We demonstrate that expansion of the CTG18.1 trinucleotide repeat in TCF4 is associated with a higher risk of corneal transplantation at a younger age, assessed for the first time in a multiracial population sample with Fuchs corneal dystrophy from the United States.

  9. Nuclear TCF4/TCF7L2 expression affected the survival of patients with esophageal squamous cell carcinoma (ESCC). Positive expression of TCF4/TCF7L2 was correlated with a poor prognosis after a curative operation in patients with ESCC.

  10. The results provide a strong evidence for independent association between type 2 diabetes mellitus and SNPs for in TCF7L2 (显示 TCF7L2 抗体) and SLC30A8 (显示 SLC30A8 抗体).

Mouse (Murine) Transcription Factor 4 (TCF4) interaction partners

  1. We report that TCF4 comprises two transcriptional isoforms, both of which are required for optimal plasmacytoid DC development in vitro

  2. these data identified E2A (显示 TCF3 抗体) and E2-2 as central regulators of B cell immunity.

  3. down-regulation of Id3 (显示 ID3 抗体) in B cells is essential for releasing E2A (显示 TCF3 抗体) and E2-2, which in a redundant manner are required for antigen-induced B cell differentiation.

  4. TCF7L2 (显示 TCF7L2 抗体) mediates canonic Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling and c-Myc (显示 MYC 抗体) upregulation during abnormal cardiac remodeling in heart failure and suppression of Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) to c-Myc (显示 MYC 抗体) axis can be explored for preventing and treating heart failure.

  5. TCF-4 as a co-activator of p65 (显示 NFkBP65 抗体) in the potentiation of proinflammatory cytokine production in macrophages and aggravation of high-fat diet induced chronic inflammation and insulin (显示 INS 抗体) resistance in mice.

  6. These findings suggest a unique role for Tcf7l2 (显示 TCF7L2 抗体) in generating distinct neuronal phenotypes from homogeneous progenitor population.

  7. Tcf7l2 (显示 TCF7L2 抗体) may be involved in maintenance of stem/progenitor cells properties.

  8. Data indicate that upregulation of E2-2 protein markedly attenuated the inhibitor of DNA-binding 1 (ID1 (显示 ID1 抗体))-mediated increase in endothelial progenitor cells (EPCs) proliferation and migration.

  9. results indicate that miR (显示 MLXIP 抗体)-181a-5p promotes 3T3-L1 preadipocyte differentiation and adipogenesis through regulating TGFbeta (显示 TGFB1 抗体)/Smad (显示 SMAD1 抗体) and Wnt (显示 WNT2 抗体) signaling pathway by directly targeting Smad7 (显示 SMAD7 抗体) and Tcf7l2 (显示 TCF7L2 抗体)

  10. Tcf7l2 (显示 TCF7L2 抗体) protein levels decline upon initiation of endocrine differentiation in vivo, disclosing the downregulation of this factor in the developing endocrine compartment.

TCF4 抗原简介

Antigen Summary

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.

Alternative names and synonyms associated with TCF4

  • transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2) 抗体
  • transcription factor 4 (tcf4) 抗体
  • transcription factor 4 (TCF4) 抗体
  • transcription factor 4 (Tcf4) 抗体
  • transcription factor 7 like 2, T cell specific, HMG box (Tcf7l2) 抗体
  • transcription factor 7-like 2 (T-cell specific, HMG-box) (LOC396347) 抗体
  • 5730422P05Rik 抗体
  • ASP-I2 抗体
  • bHLHb19 抗体
  • E2-2 抗体
  • e2-A 抗体
  • E2.2 抗体
  • GE2 抗体
  • ITF-2 抗体
  • ITF-2b 抗体
  • ITF2 抗体
  • ME2 抗体
  • MITF-2A 抗体
  • MITF-2B 抗体
  • mTcf-4B 抗体
  • mTcf-4E 抗体
  • PTHS 抗体
  • SEF-2 抗体
  • SEF2 抗体
  • SEF2-1 抗体
  • SEF2-1A 抗体
  • SEF2-1B 抗体
  • Tcf-4 抗体
  • Tcf4 抗体
  • TCF4B 抗体
  • TCF4E 抗体
  • TCF7L2 抗体
  • TFE 抗体
  • XE2 抗体
  • Xtcf-4 抗体
  • Xtcf4 抗体

Protein level used designations for TCF4

transcription factor 7-like 2 (T-cell specific, HMG-box) , transcription factor 4 , transcription factor 4-like , tcf4l , helix-loop-helix transcription factor , SL3-3 enhancer factor 2 , class B basic helix-loop-helix protein 19 , immunoglobulin transcription factor 2 , ITF-2 , TCF-4 , thyroglobulin promoter transcription factor TFE , transcriptional factor 4 , MITF-2 , Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2) , class A helix-loop-helix transcription factor ME2 , immunoglobulin transcription factor-2 , R8f DNA-binding protein , RITF-2 , SEF-2 , HMG box transcription factor 4 , T-cell factor 4 , T-cell-specific transcription factor 4 , mTCF-4 , transcription factor 7-like 2 , transcription factor 7-like 2, T-cell specific, HMG-box , transcription factor Tcf4 , T-cell factor-4 variant A , T-cell factor-4 variant B , T-cell factor-4 variant C , T-cell factor-4 variant D , T-cell factor-4 variant E , T-cell factor-4 variant F , T-cell factor-4 variant G , T-cell factor-4 variant H , T-cell factor-4 variant I , T-cell factor-4 variant J , T-cell factor-4 variant K , T-cell factor-4 variant L , T-cell factor-4 variant M , T-cell factor-4 variant X2 , hTCF-4

GENE ID SPECIES
100049930 Equus caballus
100445658 Pongo abelii
100526651 Danio rerio
373726 Xenopus laevis
6925 Homo sapiens
403949 Canis lupus familiaris
534935 Bos taurus
21413 Mus musculus
84382 Rattus norvegicus
100511671 Sus scrofa
21416 Mus musculus
395508 Gallus gallus
6934 Homo sapiens
396347 Gallus gallus
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