anti-人 FZD8 抗体 for Western Blotting

Recommended FZD8 Antibody (supplied by: Log in to see )

抗原
Frizzled Family Receptor 8 (FZD8) 抗体
  • FZ-8
  • FZD8
  • cFz-8
  • Fz-8
  • frizzled8
  • xfz8
  • Xfz8
  • frizzled-8
  • hfz8
  • hFZ8
  • fzd8
  • Fz8
  • frizzled family receptor 5
  • frizzled family receptor 8
  • frizzled homolog 8 (Drosophila)
  • FZD5
  • fzd8-b
  • FZD8
  • fzd8
  • Fzd8
  • fzd8-a
抗原表位
N-Term
19
14
6
3
3
3
1
1
1
1
1
1
1
1
1
1
1
适用
犬, 人, 小鼠, 大鼠
64
49
23
7
6
5
3
3
2
2
宿主

47
21
17
1
克隆类型
多克隆
标记
This FZD8 antibody is un-conjugated
4
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
61
33
26
23
8
4
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

产品编号 ABIN2776728
24,451.51 ¥
(含税, 含运费)
来自4A Biotech Co.,Ltd.(本地经销商)
获取报价
中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
2.90624 ABIN1535615 IF ELISA WB Rabbit IgG Log in to see Polyclonal 1
2.90624 ABIN1535685 ELISA WB Rabbit IgG Log in to see Polyclonal 1
2.90624 ABIN250857 ICC IF IHC (p) IHC ELISA WB Goat C-Term Log in to see Polyclonal 2
2.90624 ABIN2855896 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
2.90624 ABIN2704804 IC IF IHC WB Rabbit C-Term Log in to see Polyclonal
2.90624 ABIN2465732 IHC ELISA WB Goat C-Term Log in to see Polyclonal
2.90624 ABIN4312626 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
2.90624 ABIN2562711 IHC ELISA WB Goat IgG C-Term Log in to see Polyclonal
2.90624 ABIN635838 WB Rabbit Log in to see Polyclonal
2.90624 ABIN1852954 ELISA WB Rabbit C-Term Log in to see Polyclonal
1 ABIN185522 IHC ELISA WB Goat C-Term Log in to see Polyclonal 1
1 ABIN297075 ELISA WB Goat AA 684-694 Log in to see Polyclonal
1 ABIN563593 ELISA WB Mouse AA 72-161, partial Log in to see Polyclonal 1
1 ABIN317702 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN468712 WB Rabbit AA 144-193 Log in to see Polyclonal
1 ABIN2890784 IF ELISA WB Rabbit IgG AA 31-80 Log in to see Polyclonal
1 ABIN2890828 ELISA WB Rabbit IgG AA 486-535 Log in to see Polyclonal
1 ABIN3184692 ELISA IHC WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN1455216 ELISA WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN5553157 IHC (p) WB Goat C-Term Log in to see Polyclonal

General

抗原 Frizzled Family Receptor 8 (FZD8) 抗体
抗原表位 N-Term
(19), (14), (6), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 犬, 人, 小鼠, 大鼠
(64), (49), (23), (7), (6), (5), (3), (3), (2), (2)
宿主
(47), (21), (17), (1)
克隆类型
多克隆
标记 This FZD8 antibody is un-conjugated
(4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Western Blotting (WB)
(61), (33), (26), (23), (8), (4), (1), (1)
Pubmed 3个引用可参考
Supplier Log in to see

FZD8抗体详情

FZD8目标详情 使用细节 贮存及处理 ProductDetails: References for anti-FZD8 antibody (ABIN2776728) 图像
Blocking Peptide Blocking peptide for this product available: ABIN977174
序列 PDTLCMDYNR TDLTTAAPSP PRRLPPPPPG EQPPSGSGHG RPPGARPPHR
预测反应 Dog: 100%, Human: 100%, Mouse: 93%, Rat: 92%
产品特性 This is a rabbit polyclonal antibody against FZD8. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the N terminal region of human FZD8

FZD8目标详情

FZD8抗体详情 使用细节 贮存及处理 ProductDetails: References for anti-FZD8 antibody (ABIN2776728) 图像 回页首
抗原
别名 FZD8 (FZD8 Antibody 摘要)
背景 FZD8 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Alias Symbols: FZ-8, hFZ8
Protein Interaction Partner: WNT1, LRP5, LRP6, SUMO1, GOPC, RYK,
Protein Size: 694
分子量 73 kDa
基因ID 8325
NCBI登录号 NM_031866, NP_114072
UniProt Q9H461
途径 WNT signaling

使用细节

FZD8抗体详情 FZD8目标详情 贮存及处理 ProductDetails: References for anti-FZD8 antibody (ABIN2776728) 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 694 AA

限制 仅限研究用

贮存及处理

FZD8抗体详情 FZD8目标详情 使用细节 ProductDetails: References for anti-FZD8 antibody (ABIN2776728) 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

ProductDetails: References for anti-FZD8 antibody (ABIN2776728)

FZD8抗体详情 FZD8目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Xu, Wen, Liu, Xu, Yang, Liu, Feng, An: "MicroRNA-375 suppresses human colorectal cancer metastasis by targeting Frizzled 8." in: Oncotarget, Vol. 7, Issue 26, pp. 40644-40656, 2016

Yin, Xu, Bonfil, Banerjee, Sarkar, Sethi, Reddy: "Tumor-initiating cells and FZD8 play a major role in drug resistance in triple-negative breast cancer." in: Molecular cancer therapeutics, Vol. 12, Issue 4, pp. 491-8, 2013

背景

Lu, Yamamoto, Ortega, Baltimore: "Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth." in: Cell, Vol. 119, Issue 1, pp. 97-108, 2004

图像

FZD8抗体详情 FZD8目标详情 使用细节 贮存及处理 ProductDetails: References for anti-FZD8 antibody (ABIN2776728) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibody (ABIN2776728) WB Suggested Anti-FZD8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...