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FZD1 抗体

(Frizzled Family Receptor 1 (Fzd1))
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.
FZD1 抗体  (AA 117-322) FZD1 抗体  (AA 117-322) FZD1 抗体 (AA 117-322) (ABIN7435805)

Fzd1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

FZD1 抗体  (AA 125-225) FZD1 抗体  (AA 125-225) FZD1 抗体 (AA 125-225) (ABIN7153179)

Fzd1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

FZD1 抗体  (AA 73-322) FZD1 抗体  (AA 73-322) FZD1 抗体 (AA 73-322) (ABIN7153175)

Fzd1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

FZD1 抗体 by 适用

Find FZD1 抗体 for a variety of species such as anti-Human FZD1, anti-Mouse FZD1, anti-Rat FZD1. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find FZD1 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find FZD1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

FZD1 抗体 by 抗原表位

Find FZD1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

FZD1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal FZD1 抗体. Click on a link to go to the corresponding products.

FZD1 抗体 by 克隆

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Find FZD1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular FZD1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7435805
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7153179
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7153175
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS, IHC (p), EIA
Validations
  • (4)
Cat. No. ABIN357911
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Rabbit, Rat
Application IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1048617
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6258786
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN389236
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, FACS
Validations
  • (3)
Cat. No. ABIN3001613
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
Cat. No. ABIN7188747
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN467506
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6140836
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN3042412
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN2431911
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN5013572
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN389235
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our FZD1 抗体

Yang, Yang, Li, Liu, Zou, Yuan, Xu: "Overexpression of FZD1 and CAIX are Associated with Invasion, Metastasis, and Poor-Prognosis of the Pancreatic Ductal Adenocarcinoma." in: Pathology oncology research : POR, Vol. 24, Issue 4, pp. 899-906, (2018) (PubMed).

Yu, Yerges-Armstrong, Chu, Zmuda, Zhang: "Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1." in: PLoS ONE, Vol. 11, Issue 10, pp. e0163277, (2017) (PubMed).

Zhang, Kuipers, Yerges-Armstrong, Nestlerode, Jin, Wheeler, Patrick, Bunker, Zmuda: "Functional and association analysis of frizzled 1 (FZD1) promoter haplotypes with femoral neck geometry." in: Bone, Vol. 46, Issue 4, pp. 1131-7, (2010) (PubMed).

Quélard, Lavergne, Hendaoui, Elamaa, Tiirola, Heljasvaara, Pihlajaniemi, Clément, Musso: "A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling." in: PLoS ONE, Vol. 3, Issue 4, pp. e1878, (2008) (PubMed).

Hardie, Korfhagen, Sartor, Prestridge, Medvedovic, Le Cras, Ikegami, Wesselkamper, Davidson, Dietsch, Nichols, Whitsett, Leikauf: "Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis." in: American journal of respiratory cell and molecular biology, Vol. 37, Issue 3, pp. 309-21, (2007) (PubMed).

Baksh, Boland, Tuan: "Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation." in: Journal of cellular biochemistry, Vol. 101, Issue 5, pp. 1109-24, (2007) (PubMed).

Yang, Yamasaki, Shirakata, Dai, Tokumaru, Yahata, Tohyama, Hanakawa, Sayama, Hashimoto: "Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes." in: Journal of dermatological science, Vol. 42, Issue 2, pp. 111-9, (2006) (PubMed).

Aliases for FZD1 抗体

frizzled (fz) 抗体
frizzled class receptor 1 (FZD1) 抗体
frizzled class receptor 1 (Fzd1) 抗体
frizzled class receptor 1 L homeolog (fzd1.L) 抗体
AW227548 抗体
cFz-1 抗体
CG3646 抗体
CG17697 抗体
DFz 抗体
DFZ1 抗体
DFz1 抗体
Dfz1 抗体
Dmel\\CG17697 抗体
Dm Fz1 抗体
frizzled1 抗体
Frz 抗体
frz 抗体
frz-1 抗体
frz1 抗体
FZ 抗体
Fz 抗体
Fz-1 抗体
FZ-1 抗体
Fz1 抗体
fz1 抗体
fzd1-A 抗体
fz[[1]] 抗体
Xfrizzled-1 抗体
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