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抗Mouse (Murine) CTNNB1 抗体:
抗Rat (Rattus) CTNNB1 抗体:
抗Human CTNNB1 抗体:
Human Polyclonal CTNNB1 Primary Antibody for CyTOF, FACS - ABIN4899451
Sáenz-Morales, Escribese, Stamatakis, García-Martos, Alegre, Conde, Pérez-Sala, Mampaso, García-Bermejo: Requirements for proximal tubule epithelial cell detachment in response to ischemia: role of oxidative stress. in Experimental cell research 2006
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Human Monoclonal CTNNB1 Primary Antibody for WB - ABIN1882227
Huang, Wang, Guo, Jia, Lin, Li, Wang, Chen: Approaching the intrinsic electron field-emission of a graphene film consisting of quasi-freestanding graphene strips. in Small (Weinheim an der Bergstrasse, Germany) 2011
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Human Polyclonal CTNNB1 Primary Antibody for FACS, IF - ABIN1881238
Huang, Zhou, Saberwal, Konieczna, Horvath, Katsoulidis, Platanias, Eklund: Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription. in Molecular and cellular biology 2010
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Human Polyclonal CTNNB1 Primary Antibody for FACS, IF - ABIN1881239
Chairoungdua, Smith, Pochard, Hull, Caplan: Exosome release of ?-catenin: a novel mechanism that antagonizes Wnt signaling. in The Journal of cell biology 2010
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Human Polyclonal CTNNB1 Primary Antibody for WB - ABIN1881236
Mirza, Sun, Zhao, Potula, Frey, Vogel, Malik, Zhao: FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of beta-catenin expression. in The Journal of experimental medicine 2010
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Human Polyclonal CTNNB1 Primary Antibody for WB - ABIN1881237
Teng, Wang, Wang, Wang: [Effect of siRNA-mediated beta-catenin gene on Wnt signal pathway in lung adenocarcinoma A549 cell]. in Zhonghua yi xue za zhi 2010
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Human Polyclonal CTNNB1 Primary Antibody for EIA, IF - ABIN951058
Guo, Shen, Liao, Lian, Wang: NGX6 inhibits cell invasion and adhesion through suppression of Wnt/beta-catenin signal pathway in colon cancer. in Acta biochimica et biophysica Sinica 2010
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Human Polyclonal CTNNB1 Primary Antibody for ICC, IHC (fro) - ABIN3044344
Zhao, Li, Gao, Wang, Yan, Zhan, Liu, Mao, Chen, Wang et al.: Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 3? (GSK-3?) ... in European journal of medicinal chemistry 2014
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Human Polyclonal CTNNB1 Primary Antibody for ICC, IHC (fro) - ABIN5518651
Hao, Wen, Li, Wang, Ni, Wang, Wang, Sun, Fan, Mao: LiCl inhibits PRRSV infection by enhancing Wnt/?-catenin pathway and suppressing inflammatory responses. in Antiviral research 2015
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Human Polyclonal CTNNB1 Primary Antibody for ELISA, IHC - ABIN1584165
Chen, Chian, Hsiao: Mucin-producing urothelial-type adenocarcinoma of the prostate as a mimicker of colonic adenocarcinoma: a case report and review of the literature. in International journal of surgical pathology 2012
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temporal expression of CTNNB1 mRNA during dermal wound repair in the horse
Cardiomyocyte hypertrophy is blunted with cardiac fibroblast-specific loss of beta-catenin after trans-aortic constriction in vivo.
These results collectively suggest that sustained activation of Wnt (显示 WNT2 抗体)/beta-catenin signaling in endothelial cells might be a cause of heart failure through suppressing neuregulin-ErbB (显示 EGFR 抗体) signaling.
Our findings indicate that H2O2 inhibits NaV1.5 (显示 SCN5A 抗体) expression by activating the Wnt/b-catenin signaling and beta-catenin interacts with TCF4 (显示 TCF4 抗体) to transcriptionally suppress cardiac NaV1.5 (显示 SCN5A 抗体) expression.
TGF-beta (显示 TGFB1 抗体) and beta-catenin crosstalk in proximal tubules may have a role in tubular injury in two models of chronic kidney disease
Results indicate that ablation of epithelial Wnt (显示 WNT2 抗体)/beta-catenin signaling affected epididymal epithelial cell proliferation but did not inhibit cell differentiation.
Interactions between the Wnt (显示 WNT2 抗体)/beta-catenin and the Kras/ERK (显示 EPHB2 抗体)/Foxm1 (显示 FOXM1 抗体) pathways are essential to restrict SOX9 (显示 SOX9 抗体) expression in basal cells during pulmonary branching morphogenesis
The collective results indicate that the osteoanabolic response to loading can occur on the periosteal surface when beta-cat levels are significantly reduced in Dmp1 (显示 DMP1 抗体)-expressing cells.
L. donovani triggered AKT (显示 AKT1 抗体) activation to regulate GSK-3beta (显示 GSK3b 抗体)/beta-catenin/FOXO-1 (显示 FOXO1 抗体) axis.
Barx2 (显示 BARX2 抗体) and Pax7 (显示 PAX7 抗体) regulate the canonical Wnt (显示 WNT2 抗体) target gene Axin2 (显示 AXIN2 抗体), which mediates critical feedback to terminate the transcriptional response to Wnt (显示 WNT2 抗体) signals.
NFkB/beta-catenin signaling pathway plays a key role in the regulation of breast cancer-induced bone cell activity and osteolysis.
Net1-regulated beta-catenin activation plays a crucial role in the dorsal axis formation during zebrafish development.
Wnt (显示 WNT2 抗体)/beta-catenin signaling induces expression of col12a1a/b and deposition of Collagen XII, which is necessary for axons to actively navigate the non-neural lesion site environment.
Mechanistically, Hif-3alpha2 binds to beta-catenin and destabilizes the nuclear beta-catenin complex.
Nuclear beta-catenin is an indication of an activated Wnt (显示 WNT2 抗体) pathway, therefore suggesting a possible role for Wnt (显示 WNT2 抗体) signalling during zebrafish tooth development and replacement.
Findings suggest that microRNA 19b (miR (显示 MYLIP 抗体)-19b) regulates laterality development and heart looping in embryos by targeting beta-catenin ctnnb1.
Custos binds to beta-catenin in a Wnt (显示 WNT2 抗体) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.
The role of the beta-catenin mechanosensitive pathway in mesoderm identity has been conserved over the large evolutionary distance separating zebrafish and Drosophila.
The Wnt (显示 WNT2 抗体)/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality. (Review)
This study demonstrated that beta-catenin/Wnt (显示 WNT2 抗体) signaling is initially required to activate cell-cycle re-entry in Muller glia following injury and that Wnt (显示 WNT2 抗体) signaling subsequently controls the fate of the progeny of those cell divisions.
A novel role for Eaf1 (显示 EAF1 抗体) and Eaf2 (显示 EAF2 抗体) in inhibiting canonical Wnt (显示 WNT2 抗体)/beta-catenin signaling, which might form the mechanistic basis for Eaf1 (显示 EAF1 抗体) and Eaf2 (显示 EAF2 抗体) tumor suppressor activity.
We identified the amphibian leap2 (显示 LEAP2 抗体) gene which is highly related to its mammalian orthologues at both structural and sequence levels. The gene is expressed in the embryo mostly in the endoderm-derived tissues. Accordingly it is induced in pluripotent animal cap cells by FGF, activin (显示 Actbeta 抗体) or a combination of vegT/beta-catenin.
Together, these results indicate that capsaicin inhibits the patterning of the dorso-ventral and anterior-posterior body axes of embryo by repressing PP2A (显示 PPP2R2B 抗体) and thereby down-regulating the Wnt (显示 WNT2 抗体)/beta-catenin signaling.
maternal Wnt (显示 WNT2 抗体)/STOP signaling, but not beta-catenin signaling, has a role in cleavage after fertilization and cell cycle progression
Wnt (显示 WNT2 抗体) signalling can benefit from nucleo-cytoplasmic shuttling of APC (显示 APC 抗体), Axin (显示 AXIN1 抗体) and GSK3 (显示 GSK3b 抗体), although they are in general beta-catenin antagonising proteins.
Phosphoinositide 3-kinase and Rac (显示 AKT1 抗体) polarization depend specifically on the N-cadherin (显示 CDH2 抗体)-p120 catenin (显示 CTNND1 抗体) complex, whereas myosin II light chain and actin filament polarization depend on the N-cadherin (显示 CDH2 抗体)-beta-catenin complex.
HERG (显示 KCNH2 抗体) channel activity is stimulated by beta-catenin
Zic3 (显示 ZIC3 抗体) can suppress Wnt (显示 WNT2 抗体)/beta-catenin signaling and control development of the notochord and Spemann's organizer.
Notch (显示 NOTCH1 抗体) initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3 (显示 GSK3b 抗体)
The tyrosine kinase receptor (显示 KDR 抗体), PTK7 (显示 PTK7 抗体), is implicated in beta-catenin-dependent developmental processes.
Data indicate cross-talks between MYCN (显示 MYCN 抗体) and beta-catenin signalling, which repress normal beta-catenin mediated transcriptional regulation.
mutations in TERT (显示 TERT 抗体) promoter and in CTNNB1 gene represent specific cancer signatures in the pathogenesis of viral related HCC (显示 FAM126A 抗体).
Multiple myeloma that is driven by deregulated iron homeostasis and/or Pyk2 (显示 PTK2B 抗体)/beta-cateninn signaling is susceptible to deferasirox-induced apoptosis.
Results indicate that protein disulfide isomerase family 6 (PDIA6) overexpression promoted the proliferation of HeLa cells by suppressing the phosphorylation of beta-catenin, thereby inhibiting the degradation of beta-catenin through the ubiquitin-proteasome pathway.
Results indicate that SFRP1 (显示 SFRP1 抗体) rs7832767 C > T, CTNNB1 rs2293303 C > T, and WISP1 (显示 WISP1 抗体) rs16893344 C > T were all strongly correlated with myocardial infarction (MI) susceptibility.
Data suggest that casein kinase 2 (CK2 (显示 CSNK2A1 抗体)) inhibition is a promising approach to blocking beta-catenin in MPNST cells, although combinatorial therapies may be required for maximal efficacy.
Beta-catenin knockdown inhibited cell proliferation, promoted apoptosis and suppressed cell migration in A549 and H460 cells accompanied by the decreased expression of Myc (显示 MYC 抗体), PCNA (显示 PCNA 抗体), VEGF (显示 VEGFA 抗体), CD44 (显示 CD44 抗体), MMP-9 (显示 MMP9 抗体), MMP-13 (显示 MMP13 抗体) and activated bax (显示 BAX 抗体)/caspase-3 (显示 CASP3 抗体) pathway.
Integrin alphavbeta3 (显示 ITGAV 抗体) has a role in enhancing beta-catenin signaling in acute myeloid leukemia (显示 BCL11A 抗体) harboring Fms-like tyrosine kinase-3 (显示 FLT3 抗体) internal tandem duplication mutations
lncRNA-BCAT1 (显示 BCAT1 抗体) is a tumor suppressor and that lncRNA-BCAT1 (显示 BCAT1 抗体) may be an effective prognostic biomarker in Colorectal cancer.
Enhancer of zeste homolog 2 (EZH2 (显示 EZH2 抗体)) expression is positively correlated with the expression of Wnt (显示 WNT2 抗体)/beta-catenin signaling and negatively correlated with the expression of GSK-3beta (显示 GSK3b 抗体) and TP53 (显示 TP53 抗体) in cervical cancer tissues.
Results highlight a potential role for the beta-catenin/Wnt (显示 WNT2 抗体) and Notch (显示 NOTCH1 抗体) signalling pathways during the infection of crypt cells by L. intracellularis.
Flutamide exposure led to decreased beta-catenin in corpus luteum of mid/late pregnancy.
beta-catenin signaling is involved in formation of contractile membranes by dedifferentiated retinal pigment epithelium cells.
Wnt3a (显示 WNT3A 抗体) produced a significant increase in heart valve interstitial cell number at day 4 and in the percentage of BrdU-positive nuclei at 24 h. The increase in proliferation was abolished by beta-catenin siRNA.
beta-catenin controls myocardin (显示 MYOCD 抗体)-related transcription factor-dependent transcription and emerges as a critical regulator of an array of cytoskeletal genes
beta-Catenin plays a critical role in mediating TGF-beta1 (显示 TGFB1 抗体)-induced myofibroblast differentiation in aortic valve interstitial cells.
scratching-induced injury and repair of bronchial epithelial cells may involve inhibition of Glycogen synthase kinase 3beta activity which can lead to activation of the downstream signaling through beta-catenin
Data show that Wnt3a (显示 WNT3A 抗体) can inhibit the adipogenic differentiation of porcine AMSCs, and suggest that Wnt (显示 WNT2 抗体)/beta-catenin signaling inhibits adipogenic differentiation potential and alters the cell fate from adipocytes to osteoblasts.
TNF-alpha (显示 TNF 抗体) inhibits adipogenesis through stabilization of beta-catenin protein in porcine preadipocytes.
Bovine herpesvirus 1 transiently increased beta-catenin protein levels in bovine kidney cells, but not in rabbit skin cells.
These results demonstrate that activation of AKT (显示 AKT1 抗体) is required for gonadotropin regulation of CTNNB1 accumulation and subsequent ovarian E2 production.
beta-catenin, a transcription factor activated by the canonical Wnt signaling pathway, was frequently detected in bovine herpesvirus 1 ORF2-positive trigeminal ganglionic neurons of latently infected, but not mock-infected, calves.
These data demonstrate for the first time that FSH (显示 BRD2 抗体) regulates CTNNB1 protein and WNT2 (显示 WNT2 抗体) mRNA expressions in bovine granulosa cells, suggesting a potential role of canonical WNT (显示 WNT2 抗体) signaling in ovarian steroidogenesis and follicular growth of cattle.
These data provide evidence that testosterone increases cellular beta-catenin content which promotes the expression of beta-catenin-targeted genes and myogenesis in the muscle-derived stem cells of cattle.
that beta-catenin is a plasma membrane-associated protein (显示 PDZK1IP1 抗体) in airway smooth muscle that regulates active tension development, presumably by stabilizing cell-cell contacts and thereby supporting force transmission between neighboring cells.
This study demonstrated a relationship between the timing of the development of in vitro-produced bovine embryos and the distribution and localization of the junction protein beta-catenin.
TGF-beta3 (显示 TGFB3 抗体) induces the chondrogenic differentiation of pericytes by inducing Wnt (显示 WNT2 抗体)/beta-catenin signaling and T-cell factor-induced gene transcription.
cAMP/PKA regulation of GSK3beta (显示 GSK3b 抗体)/beta-catenin signaling contributes to the increase in progesterone production in corpus luteum.
Palmatin effect on osteoarthritis is likely mediated via the Wnt (显示 WNT2 抗体)/beta-catenin and Hedgehog (显示 SHH 抗体) signaling
These results collectively showed that 2-Deoxy-D-glucose regulates dedifferentiation via beta-catenin pathway in rabbit articular chondrocytes.
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
catenin beta 1 subunit
, catenin beta-1
, beta catenin 1
, catenin (cadherin-associated protein), beta 1, 88kDa
, catenin beta-1-like
, catenin (cadherin associated protein), beta 1, 88kDa
, catenin beta
, beta catenin