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Human PGF ELISA Kit for Sandwich ELISA - ABIN625346
Zhou, Qi: PLGF inhibition impairs metastasis of larynx carcinoma through MMP3 downregulation. in Tumour biology 2014
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Human PGF ELISA Kit for Sandwich ELISA - ABIN414914
Li, Wang, Zhang, Zhao, Huang, Wu, Li, Li, Liu, Cao, Dai, Fang, Shang, Cao, Zhao, Chen: Elevated PLGF contributes to small-cell lung cancer brain metastasis. in Oncogene 2013
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Human PGF ELISA Kit for Sandwich ELISA - ABIN2685187
Luttun, Tjwa, Moons, Wu, Angelillo-Scherrer, Liao, Nagy, Hooper, Priller, De Klerck, Compernolle, Daci, Bohlen, Dewerchin, Herbert, Fava, Matthys, Carmeliet, Collen, Dvorak, Hicklin, Carmeliet: Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. in Nature medicine 2002
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Mouse (Murine) PGF ELISA Kit for Sandwich ELISA - ABIN415609
Luo, Uehara, Zhang, Das, Olsen, Holt, Simonis, Jackman, Singh, Miya, Huang, Ahmed, Bastos-Carvalho, Le, Mamalis, Chiodo, Hauswirth, Baffi, Lacal, Orecchia, Ferrara, Gao, Young-Hee, Fu, Owen et al.: Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. ... in eLife 2013
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Human PGF ELISA Kit for Sandwich ELISA - ABIN456163
Li, Liu, Bin, Wang, Chen, Xiu, Pei, Lai, Chen, Fan, Xie, Tao, Wu: Mutant hypoxia inducible factor-1? improves angiogenesis and tissue perfusion in ischemic rabbit skeletal muscle. in Microvascular research 2011
Rat (Rattus) PGF ELISA Kit for Sandwich ELISA - ABIN416339
Zhang, Zhao, Yuan, Wu, Jiang, Luo: Placenta growth factor contributes to cell apoptosis and epithelial-to-mesenchymal transition in the hyperoxia-induced acute lung injury. in Life sciences 2016
Lower maternal PlGF concentration is associated with intrapartum fetal compromise and poorer condition of the newborn. Maternal PlGF levels may be useful as a component of a risk stratification tool for intrapartum fetal compromise in apparently 'low risk' term pregnancies prior to labour.
Study provides mechanistic and clinical evidence that decreased PLGF levels in the placenta after in utero alcohol exposure are associated to brain angiogenesis defects. Measurement of PLGF levels at birth in the placenta or the fetal blood may serve as a predictive marker for subsequent neurodevelopmental outcomes of exposed fetuses.
This effect was reversed by the addition of PlGF neutralising antibody to the conditioned medium.
Results show that both FLT1 (显示 FLT1 ELISA试剂盒) and PGF are overexpressed in the circulating tumor cells (CTCs) of patients with breast cancer. Also, a functional interaction of sFlt1 (显示 FLT1 ELISA试剂盒) and PGF was found, suggesting that their overexpression in tumor cells inhibits CTCs entering the peripheral blood.
Identify a novel cis (显示 CISH ELISA试剂盒)-acting sequence (-369 to -320) at the placental growth factor promoter, which was critical for mediating the basal and DLX3 (显示 DLX3 ELISA试剂盒)/GCM1 (显示 GCM1 ELISA试剂盒)-dependent PGF promoter activities.
Low PlGF identifies small fetuses with significant underlying placental pathology and is a promising tool for antenatal discrimination of fetal growth retardation from fetuses who are constitutionally-small.
Serum and urinary sFlt-1 and sFlt-1/PLGF ratios in severe preeclampsia patients were significantly higher than those in the mild preeclampsia group, and mild preeclampsia patients were significantly higher than controls. The serum and urinary PLGF levels in severe preeclampsia patients were significantly lower than mild preeclampsia patients, and mild preeclampsia patients had significantly lower PLGF levels than controls
ROS (显示 ROS1 ELISA试剂盒) activation of the MAPK (ERK (显示 MAPK1 ELISA试剂盒)-1 (显示 MAPK3 ELISA试剂盒)/2)/Egr-1 (显示 EGR1 ELISA试剂盒) pathway is a main player in the regulatory mechanism for cigarette smoke extract-induced PlGF production. Antioxidants could partly abolish these effects.
Both the TNF-alpha (显示 TNF ELISA试剂盒)/IL-10 (显示 IL10 ELISA试剂盒) and sFlt-1/PlGF ratios were higher in placental homogenate of early-onset Preeclampsia (PE) than late-onset PE and control groups. The more severe lesions and the imbalance between TNF-alpha (显示 TNF ELISA试剂盒)/IL-10 (显示 IL10 ELISA试剂盒) and PlGF/sFlt-1 in placentas from early-onset PE allows differentiation of early and late-onset PE and suggests higher placental impairment in early-onset PE
PlGF is abundant in the human endometrium, and secreted into the uterine lumen where it mediates functional changes in cellular adhesion with important roles in implantation
PGF (显示 PTGFR ELISA试剂盒) deficiency is associated with impaired cerebral vascular development in mice.
PlGF inhibition attenuates PERK (显示 EIF2AK3 ELISA试剂盒) activation, likely by tempering hypoxia in HCC (显示 FAM126A ELISA试剂盒) via vessel normalisation. The UPR is able to regulate PlGF expression, suggesting the existence of a feedback mechanism for hypoxia-mediated UPR
Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13 (显示 IL13 ELISA试剂盒).
Data indicate that placental growth factor (PlGF) is needed in the spleen to allow the activation of T cells and blood pressure raising.
Placental growth factor promotes differentiation of bone marrow-derived macrophages and enhanced vascular endothelial cell proliferation.
PLGF in LC cells induced macrophage polarization in vivo, and significantly promoted the growth of LC.
PLGF is upregulated in vascular cells in response to fluid shear stress.
Data suggests that PLGF may target islet endothelia to release growth factors activating PI3k signalling in beta cells to increase their proliferation. In Pre-Eclampsia, PLGF reduction impairs these processes resulting in gestational diabetes mellitus.
The neutrophil elastase (显示 ELANE ELISA试剂盒)-PlGF-JNK (显示 MAPK8 ELISA试剂盒)/PKCdelta (显示 PKCd ELISA试剂盒) pathway contributes to the pathogenesis of lung epithelial cell apoptosis and emphysema.
Study reports polymorphisms in the bovine PGF gene significantly associated with the maternal effect (显示 NLRP5 ELISA试剂盒) on stillbirth and calving ease in animals under selection.
placenta growth factor expression is regulated by both VEGF (显示 VEGFA ELISA试剂盒) and hyperglycaemia via VEGFR-2 (显示 KDR ELISA试剂盒)
This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.
placental growth factor, vascular endothelial growth factor-related protein
, placenta growth factor
, placenta growth factor-like