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抗Human S100A8 抗体:
抗Rat (Rattus) S100A8 抗体:
抗Mouse (Murine) S100A8 抗体:
Human Monoclonal S100A8 Primary Antibody for EIA, IHC (fro) - ABIN111891
Odink, Cerletti, Brüggen, Clerc, Tarcsay, Zwadlo, Gerhards, Schlegel, Sorg: Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. in Nature 1987
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Human Monoclonal S100A8 Primary Antibody for EIA, IHC (fro) - ABIN111890
Brandtzaeg, Jones, Flavell, Fagerhol: Mac 387 antibody and detection of formalin resistant myelomonocytic L1 antigen. in Journal of clinical pathology 1989
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Mouse (Murine) Polyclonal S100A8 Primary Antibody for IF (p), IHC (p) - ABIN749273
Nguyen, Fentress, Qiu, Yun, Cox, Chawla: Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes. in Science (New York, N.Y.) 2013
Human Monoclonal S100A8 Primary Antibody for IA, FACS - ABIN2192036
Robinson, Tessier, Poulsom, Hogg: The S100 family heterodimer, MRP-8/14, binds with high affinity to heparin and heparan sulfate glycosaminoglycans on endothelial cells. in The Journal of biological chemistry 2002
Human Polyclonal S100A8 Primary Antibody for ELISA, WB - ABIN4242803
Eggers, Sikora, Lorenz, Taubert, Moobed, Baumann, Stangl, Stangl: RAGE-dependent regulation of calcium-binding proteins S100A8 and S100A9 in human THP-1. in Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2011
Human Polyclonal S100A8 Primary Antibody for IHC, IHC (p) - ABIN4351730
Ellis, LaRocque, Uddin, Krastins, Mayo-Smith, Sarracino, Karlsson, Rahman, Shirin, Bhuiyan, Chowdhury, Khan, Ryan, Calderwood, Qadri, Harris: Comparative proteomic analysis reveals activation of mucosal innate immune signaling pathways during cholera. in Infection and immunity 2015
Data suggest that fecal calprotectin may be a potential biomarker to identify patients with ankylosing spondylitis (AS) at risk of developing inflammatory bowel disease (IBD).
Elevated S100A8 and S100A9 (显示 S100A9 抗体) gene expression in SP-infected HMEECs and in the middle ear mucosa of OM, minor co-localized with neutrophil markers suggests that middle ear epithelial cell secretion of S100A8 and S100A9 (显示 S100A9 抗体) may play a role in the pathogenesis of recurrent and chronic OM
results of this study support an additional role of calprotectin in assessing inflammatory activity in patients with RA
Data show that E3 ubiquitin ligase (显示 MUL1 抗体) HRD1 (HRD1 (显示 SYVN1 抗体)) decreased the protein level of S100A8 through ubiquitination.
High S100A8 expression is associated with glioblastoma.
This study implicates S100A8 and S100A9 (显示 S100A9 抗体) as important mediators of tumor cell aggressiveness, and highlights the therapeutic potential of S100A8 and S100A9 (显示 S100A9 抗体) for interference of metastasis.
Data indicate a statistical correlation between fecal calprotectin (FC) and gastrointestinal graft-versus-host disease (GvHD).
Perinatal alarmins S100A8 and S100A9 (显示 S100A9 抗体) specifically altered MyD88 (显示 MYD88 抗体)-dependent proinflammatory gene programs. S100 programming prevented hyperinflammatory responses without impairing pathogen defense. TRIF (显示 TRIM69 抗体)-adaptor-dependent regulatory genes remained unaffected by perinatal S100 programming and responded strongly to lipopolysaccharide, but were barely expressed.
Expression of S100A8, S100A9 (显示 S100A9 抗体) and S100A12 (显示 S100A12 抗体) is modulated by eicosapentaenoic acid and docosahexaenoic acid during Inflammation in adipose tissue and mononuclear cells.
High S100A8 expression is associated with lung metastasis in malignant melanoma.
Data suggest that up-regulation of S100A8 and S100A9 (显示 S100A9 抗体) is a key component of early endometrial response to uterine involution in the post-partum period and to prevent chronic endometritis/uterine inflammation; up-regulation can be influenced by diet.
Study verified porcine calprotectin (S100A8/A9) expression at the protein level in multiple Haemophilus parasuis infected tissues and explored their molecular characterization.
Neutrophil-derived S100A8/A9 promotes thrombocytosis in diabetic mice
Perinatal alarmins S100A8 and S100A9 (显示 S100A9 抗体) specifically altered MyD88 (显示 MYD88 抗体)-dependent proinflammatory gene programs. S100 programming prevented hyperinflammatory responses without impairing pathogen defense. TRIF (显示 RNF138 抗体)-adaptor-dependent regulatory genes remained unaffected by perinatal S100 programming and responded strongly to lipopolysaccharide, but were barely expressed.
S100a8 upregulation triggers NF-kappaB (显示 NFKB1 抗体) signal pathway through RAGE (显示 AGER 抗体) and TLR4 (显示 TLR4 抗体), in response to laser-induced dermis wound healing.
Although MRP-8/-14 expression is highly increased in experimental, these proteins do not contribute to the pathogenesis in the effector phase of epidermolysis bullosa acquisita and bullous pemphigoid (显示 DST 抗体).
TLR4 (显示 TLR4 抗体), TLR2 (显示 TLR2 抗体) also contributed to Mrp8-induced inflammatory response and tolerance.
S100A8 appears to play a crucial role in the activation of the TLR4 (显示 TLR4 抗体)/MD-2 (显示 LY96 抗体) pathway and the promotion of a tumor growth-enhancing immune microenvironment.
Rps14 (显示 RPS14 抗体) haploinsufficiency in del(5q) myelodysplastic syndrome is linked to activation of the innate immune system and induction of S100A8-S100A9 (显示 S100A9 抗体) expression, leading to a p53 (显示 TP53 抗体)-dependent erythroid differentiation defect.
S100A8 is primarily produced from CXCR2 (显示 CXCR2 抗体)-expressing CD11b (显示 ITGAM 抗体)(+)Gr-1 (显示 GSR 抗体)(high) cells, and it upregulates TNF-alpha (显示 TNF 抗体) production in CD11b (显示 ITGAM 抗体)(+)F4/80(+) cells through cellular cross-talk, which is an important mechanism in the development of Nonalcoholic fatty liver disease
Alarmins S100A8/S100A9 (显示 S100A9 抗体) aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis.
This study identified Mrp8/14 and TLR4 (显示 TLR4 抗体) as important modulators of the leukocyte recruitment cascade during inflammation via integrin beta2.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
, S100 calcium-binding protein A8 (calgranulin A)
, calgranulin A
, calprotectin L1L subunit
, cystic fibrosis antigen
, leukocyte L1 complex light chain
, migration inhibitory factor-related protein 8
, protein S100-A8
, urinary stone protein band A
, S100 calcium binding protein A8 (calgranulin A)
, S100 calcium binding protein A8
, S100 calcium-binding protein A8
, neutrophil cytosolic 7 kDa protein
, chemotactic S100 protein
, chemotactic cytokine CP-10
, pro-inflammatory S100 cytokine
, macrophage migration inhibitory factor-related protein-8