anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7) 抗体产品概述

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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 抗体 (ABCB7)
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别名:
AA517758, Abc7, ABCB7, ASAT, Atm1p, AU019072, CG7955, dABCB7, Dmel\\CG7955, EST140535, fc20c02, GB11034, wu:fc20c02

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引用最多的anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 抗体

  1. Human Polyclonal ABCB7 Primary Antibody for EIA, IHC (p) - ABIN358593 : Allikmets, Raskind, Hutchinson, Schueck, Dean, Koeller: Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A). in Human molecular genetics 1999 (PubMed)
    Show all 5 references for 358593

  2. Human Polyclonal ABCB7 Primary Antibody for IHC (p), WB - ABIN390062 : Csere, Lill, Kispal: Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p. in FEBS letters 1999 (PubMed)
    Show all 5 references for 390062

  3. Human Polyclonal ABCB7 Primary Antibody for IHC, ELISA - ABIN1534672 : Bekri, Kispal, Lange, Fitzsimons, Tolmie, Lill, Bishop: Human ABC7 transporter: gene structure and mutation causing X-linked sideroblastic anemia with ataxia with disruption of cytosolic iron-sulfur protein maturation. in Blood 2000 (PubMed)
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更多抗ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7的相互作用对抗体

Fruit Fly (Drosophila melanogaster) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7) interaction partners

  1. No ABCB7 mutations were found among sixty CSA probands examined

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7) interaction partners

  1. data support a model in which cycloheximide -induced downregulation of the iron exporter ABCB7 mRNA transcript resulting from aberrant splicing caused by mutant SF3B1 (显示 SF3B2 抗体) underlies the increased mitochondrial iron accumulation found in MDS (显示 PAFAH1B1 抗体) patients with ring sideroblasts

  2. A missense mutation in the ABCB7 is a major causative factor of the cerebellar hypoplasia/atrophy found in affected individuals of a Buryat family who had no evidence of sideroblastic anemia.

  3. findings support that ABCB7 is implicated in the phenotype of acquired RARS (显示 RARS 抗体) and suggest a relation between SF3B1 (显示 SF3B2 抗体) mutations and ABCB7 downregulation

  4. We describe a fourth family with X-linked sideroblastic anemia and ataxia and a novel mutation in the ABCB7 gene

  5. loss of the ABCB7 gene may be a pathogenetic factor underlying mitochondrial iron accumulation in RARS (显示 RARS 抗体) patients with idicXq13.

  6. ABCB7 may have a role in refractory anemia with ring sideroblasts

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7) interaction partners

  1. ABC7 positively regulates the expression of extramitochondrial thioredoxin (显示 TXN 抗体) & that of an intramitochondrial iron-sulfur-containing protein, ferrochelatase (显示 FECH 抗体). ABC7 contributes to the production of heme during the differentiation of erythroid cells.

  2. Abcb7 is an essential gene associated with X-linked parent of origin lethality in mice and required for development or maintenance of adult cell lineages.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7) 抗原简介

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7)

  • CG7955 gene product from transcript CG7955-RA (ABCB7) 抗体
  • ATP-binding cassette subfamily B, member 7 (ABCB7) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 7 (ABCB7) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 7 (abcb7) 抗体
  • ABCB7-like (LOC100367778) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 7 (Abcb7) 抗体
  • ATP-binding cassette, subfamily B (MDR/TAP), member 7 (Abcb7) 抗体
  • AA517758 抗体
  • Abc7 抗体
  • ABCB7 抗体
  • ASAT 抗体
  • Atm1p 抗体
  • AU019072 抗体
  • CG7955 抗体
  • dABCB7 抗体
  • Dmel\\CG7955 抗体
  • EST140535 抗体
  • fc20c02 抗体
  • GB11034 抗体
  • wu:fc20c02 抗体

Protein level used designations for ABCB7

ABCB7-PA , ABCB7-PB , CG7955-PA , CG7955-PB , ATP-binding cassette, sub-family B, member 7 , ATP-binding cassette, sub-family B (MDR/TAP), member 7 , ATP-binding cassette sub-family B member 7, mitochondrial , ABCB7-like , ATP-binding cassette sub-family B member 7, mitochondrial-like , ABC transporter 7 protein , ATP-binding cassette transporter 7 , ATP-binding cassette 7 , ATP-binding cassette, sub-family B, member 7, mitochondrial

GENE ID SPECIES
38193 Drosophila melanogaster
412749 Apis mellifera
422326 Gallus gallus
473672 Pan troglodytes
533669 Bos taurus
566515 Danio rerio
704034 Macaca mulatta
100010563 Monodelphis domestica
100060544 Equus caballus
100351866 Oryctolagus cuniculus
100367778 Saccoglossus kowalevskii
100415470 Callithrix jacchus
100446826 Pongo abelii
100467128 Ailuropoda melanoleuca
22 Homo sapiens
11306 Mus musculus
491967 Canis lupus familiaris
100157043 Sus scrofa
302395 Rattus norvegicus
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