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TIRAP 抗体

(Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described. [provided by RefSeq, Jul 2008].
TIRAP 抗体  (AA 1-221) TIRAP 抗体  (AA 1-221) TIRAP 抗体 (AA 1-221) (ABIN7441712)

TIRAP 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

TIRAP 抗体  (AA 1-221) TIRAP 抗体  (AA 1-221) TIRAP 抗体 (AA 1-221) (ABIN6149192)

TIRAP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

TIRAP 抗体  (AA 1-221) TIRAP 抗体  (AA 1-221) TIRAP 抗体 (AA 1-221) (ABIN7172290)

TIRAP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

TIRAP 抗体 by Grade

Find TIRAP 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

TIRAP 抗体 by 适用

Find TIRAP 抗体 for a variety of species such as anti-Human TIRAP, anti-Mouse TIRAP, anti-Rat TIRAP. The species listed below are among those available. Click on a link to go to the corresponding products.

TIRAP 抗体 by 应用范围

Find TIRAP 抗体 validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

TIRAP 抗体 by 抗体来源

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TIRAP 抗体 by 抗原表位

Find TIRAP 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TIRAP 抗体 by 克隆形成能力

Find available monoclonal or polyclonal TIRAP 抗体. Click on a link to go to the corresponding products.

TIRAP 抗体 by 克隆

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TIRAP 抗体 by 标记

Find TIRAP 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TIRAP 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro), ICC
Validations
  • (8)
Cat. No. ABIN7441712
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN6149192
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7172290
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (1)
  • (2)
Cat. No. ABIN949800
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7270842
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN297782
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN873277
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN872309
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN880289
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7182878
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Horse, Human, Monkey, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6741881
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN3182983
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN184633
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN531974
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN500925
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our TIRAP 抗体

Blanchard, Loomis, Bhosle, Vanover, Baumhof, Pitard, Zurla, Santangelo: "Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA." in: Molecular therapy. Nucleic acids, Vol. 14, pp. 52-66, (2019) (PubMed).

Du, Qiao, Chen, Chen, Liu, Lin, Wang, Xie: "Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes." in: Frontiers in molecular neuroscience, Vol. 10, pp. 409, (2017) (PubMed).

Rolf, Kariminia, Ivison, Reid, Schultz: "Heterodimer-specific TLR2 stimulation results in divergent functional outcomes in B-cell precursor acute lymphoblastic leukemia." in: European journal of immunology, Vol. 45, Issue 7, pp. 1980-90, (2015) (PubMed).

Wang, Schwab, Fan, Seagroves, Buolamwini: "Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer." in: Cancer prevention research (Philadelphia, Pa.), Vol. 6, Issue 5, pp. 437-47, (2013) (PubMed).

Nguyen, Kim, Kim, Le, Kim, Kang, Hasegawa, Kanaho, Jou, Lee et al.: "Phosphatidylinositol 4-phosphate 5-kinase ? facilitates Toll-like receptor 4-mediated microglial inflammation through regulation of the Toll/interleukin-1 receptor domain-containing adaptor protein ..." in: The Journal of biological chemistry, Vol. 288, Issue 8, pp. 5645-59, (2013) (PubMed).

Farina, Krumbholz, Giese, Hartmann, Aloisi, Meinl: "Preferential expression and function of Toll-like receptor 3 in human astrocytes." in: Journal of neuroimmunology, Vol. 159, Issue 1-2, pp. 12-9, (2005) (PubMed).

Andreakos, Sacre, Smith, Lundberg, Kiriakidis, Stonehouse, Monaco, Feldmann, Foxwell: "Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP." in: Blood, Vol. 103, Issue 6, pp. 2229-37, (2004) (PubMed).

Vogel, Fitzgerald, Fenton: "TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression." in: Molecular interventions, Vol. 3, Issue 8, pp. 466-77, (2004) (PubMed).

McGettrick, ONeill: "The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction." in: Molecular immunology, Vol. 41, Issue 6-7, pp. 577-82, (2004) (PubMed).

ONeill, Fitzgerald, Bowie: "The Toll-IL-1 receptor adaptor family grows to five members." in: Trends in immunology, Vol. 24, Issue 6, pp. 286-90, (2003) (PubMed).

Aliases for TIRAP 抗体

toll-interleukin 1 receptor (TIR) domain containing adaptor protein (tirap) 抗体
TIR domain containing adaptor protein (TIRAP) 抗体
toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog (tirap.L) 抗体
TIR domain containing adaptor protein (Tirap) 抗体
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (Tirap) 抗体
AA407980 抗体
BACTS1 抗体
C130027E04Rik 抗体
mal 抗体
Mal 抗体
MyD88-2 抗体
Tlr4ap 抗体
wyatt 抗体
Wyatt 抗体
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