anti-LY96 (LY96) 抗体产品概述

Full name:
anti-Lymphocyte Antigen 96 抗体 (LY96)
在www.antibodies-online.cn可供106 Lymphocyte Antigen 96 (LY96) 抗体的22不同的供货商。 再加上,我们可以发LY96 试剂盒 (18)LY96 蛋白 (13)和数多这个蛋白质的别的产品。 总共145 LY96产品已列进来了。
别名:
ESOP-1, Ly-96, MD-2, Md2

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引用最多的anti-LY96 抗体

  1. Human Polyclonal LY96 Primary Antibody for IHC (p), IHC - ABIN252602 : Kunda, Cavicchia, Acosta: Lipopolysaccharides and trophic factors regulate the LPS receptor complex in nodose and trigeminal neurons. in Neuroscience 2014 (PubMed)
    Show all 4 references for 252602

  2. Human Monoclonal LY96 Primary Antibody for Func - ABIN1108191 : Pugin, Stern-Voeffray, Daubeuf, Matthay, Elson, Dunn-Siegrist: Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock. in Blood 2004 (PubMed)
    Show all 4 references for 1108191

  3. Human Monoclonal LY96 Primary Antibody for Func, EIA - ABIN1108192 : Viriyakosol, McCray, Ashbaugh, Chu, Jia, Weiss, Kirkland: Characterization of monoclonal antibodies to human soluble MD-2 protein. in Hybridoma (2005) 2007 (PubMed)

  4. Human Polyclonal LY96 Primary Antibody for IHC (fro), WB - ABIN265133 : ONeill, Fitzgerald, Bowie: The Toll-IL-1 receptor adaptor family grows to five members. in Trends in immunology 2003 (PubMed)

更多抗LY96的相互作用对抗体

Human Lymphocyte Antigen 96 (LY96) interaction partners

  1. MD2 plays an important role in induction of allergic sensitization to cat dander and common pollens relevant to human allergic diseases.

  2. we report that exogenous CnB (显示 PPP3R1 抗体) is taken up by cells in a time- and concentration-dependent manner via clathrin-dependent receptor-mediated internalization. Our findings further confirm that uptake is mediated by the TLR4 (显示 TLR4 抗体)/MD2 complex together with the co-receptor CD14 (显示 NDUFA2 抗体)

  3. In this study, a novel naturally occurring spliceosome of human MD2, termed as MD2-T3, has been identified.

  4. Results show that cigarette smoke may alter innate immune responses reducing the expression of the MD2, a molecule with an important role in TLR4 (显示 TLR4 抗体) signaling.

  5. Predominantly hydrophobic interactions between MD-2 and TLR4 (显示 TLR4 抗体) contribute to the stabilization of the TLR4 (显示 TLR4 抗体)/MD-2/metal ion complex in a conformation that enables activation.

  6. The intensity of the intra-amniotic inflammatory response to bacteria or perhaps to other TLR4 (显示 TLR4 抗体) ligands may be facilitated through synthesis and release of sMD2 (显示 SNRPD2 抗体) by the amniochorion.

  7. Three genes (LY96, IL8 (显示 IL8 抗体) DPR (显示 DACT1 抗体)) were significantly downregulated over time. This finding was confirmed in a validation cohort of stroke patients (n=8).

  8. The study revealed the impact of specific residues and regions of MD-2 on the binding of lipolysaccharides and TLR4 (显示 TLR4 抗体).

  9. Gene polymorphisms of MD2 and GM2A (显示 GM2A 抗体) were associated with the occurrence or severity of neonatal necrotizing enterocolitis.

  10. In patients undergoing CABG surgery, we found genetic polymorphisms in LY96 associated with decreased risk of postoperative AF.

Mouse (Murine) Lymphocyte Antigen 96 (LY96) interaction partners

  1. MD2 plays an important role in induction of allergic sensitization to cat dander and common pollens relevant to human allergic diseases.

  2. Oxidative stress in retinal ischemia-reperfusion injury activates TLR4 (显示 TLR4 抗体) signaling via MD2.

  3. Neoseptin-3 and lipid A form dissimilar molecular contacts to achieve receptor activation; hence strong TLR4 (显示 TLR4 抗体)/MD-2 agonists need not mimic LPS (显示 TLR4 抗体)

  4. Here we demonstrate that cholesterol binds to myeloid differentiation-2 (MD-2), a TLR4 (显示 TLR4 抗体) ancillary molecule.

  5. MD-2 is a critical regulator of the establishment of allergic airway sensitization to HDM (显示 HDAC3 抗体) in mice. Serum MD-2 may represent a potential biomarker for the amplification of allergic sensitization and allergic inflammation.

  6. Data show that myeloid differentiation factor 2 (MD-2) binds specifically to disulfide isoform of box protein 1, high mobility group (显示 SSRP1 抗体) (HMGB1 (显示 HMGB1 抗体)) to facilitate toll-like receptor 4 (TLR4 (显示 TLR4 抗体))-dependent signaling.

  7. Carbon monoxide treatment reduces the expression of the TLR4 (显示 TLR4 抗体)/MD2 complex on the surface of myeloid cells, which renders them resistant to lipopolysaccharide priming in vitro, as well as in vivo in a model of endotoxic shock.

  8. Mechanistically, engagement of MD-2 by PTX3 (显示 PITX3 抗体)-opsonized Aspergillus conidia activated the TLR4/Toll (显示 TLR4 抗体)/IL-1R domain-containing adapter inducing IFN-beta (显示 IFNB1 抗体)-dependent signaling pathway converging on IL-10 (显示 IL10 抗体).

  9. SAA3 directly binds MD-2 and activates the MyD88 (显示 MYD88 抗体)-dependent TLR4 (显示 TLR4 抗体)/MD-2 pathway.

  10. Monophosphoryl lipid A is unable to efficiently form TLR4 (显示 TLR4 抗体)/MD-2 heterotetramers, but it still needs heterotetramer formation for the full extent of signaling it is able to achieve.

LY96 抗原简介

Antigen Summary

This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with LY96

  • lymphocyte antigen 96 (LY96) 抗体
  • lymphocyte antigen 96 (Ly96) 抗体
  • ESOP-1 抗体
  • Ly-96 抗体
  • MD-2 抗体
  • Md2 抗体

Protein level used designations for LY96

myeloid differentiation protein-2 , protein MD-2 , ly-96 , myeloid differentiation factor-2 , LPS co-receptor MD-2 , lymphocyte antigen 96 , MD-2 , Protein MD-2

GENE ID SPECIES
696778 Macaca mulatta
23643 Homo sapiens
17087 Mus musculus
448830 Rattus norvegicus
613753 Bos taurus
610524 Canis lupus familiaris
420189 Gallus gallus
100729146 Cavia porcellus
100125555 Sus scrofa
100009589 Oryctolagus cuniculus
101108235 Ovis aries
100689342 Cricetulus griseus
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