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Mouse (Murine) CREB1 ELISA Kit - ABIN832415
Arora, Bhowmik, Khanam, Vohora: Oxcarbazepine and fluoxetine protect against mouse models of obsessive compulsive disorder through modulation of cortical serotonin and CREB pathway. in Behavioural brain research 2013
CREB is positively regulated by PKA and calcium-sensitive calcineurin and negatively by PKC.
The sequence of the CREB gene contains a 88 bp 5 (显示 HSPD1 ELISA试剂盒)' UTR (显示 UTS2R ELISA试剂盒), a 783 bp open reading frame encoding 261 amino acids and a 348 bp 3 (显示 BST1 ELISA试剂盒)' UTR (显示 UTS2R ELISA试剂盒).
Data indicate increasing expression for CREB, ATF1 (显示 AFT1 ELISA试剂盒), and ATF3 (显示 ATF3 ELISA试剂盒) during gastrulation.
This study showed that the induction level of IL-32 (显示 IL32 ELISA试剂盒) was increased in chronic rhinosinusitis with nasal polyps compared to normal nasal mucosa and that LPS (显示 IRF6 ELISA试剂盒)-induced IL-32 (显示 IL32 ELISA试剂盒) expression in nasal polyp-derived fibroblasts was regulated via the TLR4 (显示 TLR4 ELISA试剂盒)/JNK (显示 MAPK8 ELISA试剂盒)/AKT (显示 AKT1 ELISA试剂盒)/CREB signaling pathway.
Studies indicate that the small molecule ICG-001 selectively blocks the cAMP response element-binding (CREB) protein (CBP (显示 CREBBP ELISA试剂盒))/beta-catenin (显示 CTNNB1 ELISA试剂盒) or gamma-catenin (显示 JUP ELISA试剂盒) interaction.
Study indicates that BPA (显示 DST ELISA试剂盒) increases phosphorylated CREB in MCF-7 Cells as well as it binding to SOX2 (显示 SOX2 ELISA试剂盒) enhancer.
study concludes that miR (显示 MLXIP ELISA试剂盒)-132 regulated SIRT1 (显示 SIRT1 ELISA试剂盒)/CREB/ABCG2 (显示 ABCG2 ELISA试剂盒) signaling pathway contributing to the cisplatin resistance and might serve as a novel therapeutic target against gastric cancer
Leptin (显示 LEP ELISA试剂盒) also significantly increased cAMP levels, cAMP response element (CRE) activation, and CREB phosphorylation.
these data show the existence of functional CREB and C/EBP (显示 CEBPA ELISA试剂盒) binding sites in the human RIC8B gene promoter, a particular distribution of these sites and demonstrate a relevant role of CREB in stimulating transcriptional activity of this gene.
MALAT1 knockdown reduces reactive gliosis, Muller cell activation, and RGC survival in vivo and in vitro MALAT1-CREB binding maintains CREB phosphorylation by inhibiting PP2A (显示 PPP2R4 ELISA试剂盒)-mediated dephosphorylation, which leads to continuous CREB signaling activation.
aberrant activation of CREB-C/EBPdelta (显示 CEBPD ELISA试剂盒) axis concurring to AML (显示 RUNX1 ELISA试剂盒) onset by disrupting the myeloid cell differentiation process
miR (显示 MLXIP ELISA试剂盒)-27b-3p levels were found to be significantly negatively correlated with both NR5A2 (显示 NR5A2 ELISA试剂盒) and CREB1 levels in breast cancer tissues.
Interactions between GNB3 (显示 GNB3 ELISA试剂盒), CREB1 and negative life events were revealed. Further evidence is provided about the role of the environment in genetic vulnerability to major depression.
Ca(2 (显示 CA2 ELISA试剂盒)+) signaling pathway increases Nr4a1 (显示 NR4A1 ELISA试剂盒) expression in MA-10 Leydig cells, at least in part, by enhancing the recruitment of coactivator most likely through the MEF2 (显示 MEF2C ELISA试剂盒), AP1 (显示 JUN ELISA试剂盒), and CREB transcription factors thus demonstrating an important interplay between the Ca(2 (显示 CA2 ELISA试剂盒)+) and cAMP pathways in regulating Nr4a1 (显示 NR4A1 ELISA试剂盒) expression.
PGE2 serves as a central regulator of the Ren (显示 REN1 ELISA试剂盒)-1c gene in the principal cells of the kidney collecting ducts via the PKC (显示 PKC ELISA试剂盒)/cAMP/CREB pathway.
study revealed the involvement of CREB in B-1a cells, which was upregulated to increase the production of IL-10 (显示 IL10 ELISA试剂盒) for attenuating inflammation and organ injury, and finally improving survival during sepsis
In conclusion, glucocorticoid couples mGR (显示 GRHL1 ELISA试剂盒) with Galphas (显示 GNAS ELISA试剂盒) and triggers cAMP-PKA-CREB axis dependent on the lipid raft to stimulate BACE1 (显示 BACE ELISA试剂盒) upregulation and Abeta (显示 APP ELISA试剂盒) generation.SIGNIFICANCE STATEMENT Patients with Alzheimer's disease (AD) have been growing sharply and stress is considered as the major environment factor of AD.
CREB was found to bind to GSK3beta (显示 GSK3b ELISA试剂盒) promoter and essential for cAMP-mediated regulation of GSK3beta (显示 GSK3b ELISA试剂盒).
The NR2B (显示 GRIN2B ELISA试剂盒)-CREB-miR212/132-CRTC1 (显示 CRTC1 ELISA试剂盒)-CREB signal network plays an important role in the regulation of pain.
Therefore, our study suggests that CREB and PSD95 are novel substrates of PERK, so inhibition of PERK phosphorylation using GSK2656157 would be beneficial against memory impairment after TBI.
Our results elucidate the specific role of the transcription factors CREB, SRF, and MEF2 (显示 MEF2C ELISA试剂盒) in the depression and potentiation components of ODP in vivo, therefore better informing future attempts to find therapeutic targets for diseases where activity-dependent plasticity is disrupted.
neuronal activity promotes CREB-dependent transcription by increasing the frequency of CREB binding to highly localized genome locations
Expression of miR (显示 MLXIP ELISA试剂盒)-26a or knockdown of Klf4 (显示 KLF4 ELISA试剂盒) or Creb or C/ebpbeta (显示 CEBPB ELISA试剂盒), attenuated the survival of Mycobacterium tuberculosis in macrophages.
The expression of porcine Prdx6 (显示 PRDX6 ELISA试剂盒) gene is up-regulated by C/EBPbeta (显示 CEBPB ELISA试剂盒) and CREB.
Results suggest that cerebral hypoxia results in differential regulation of CREB protein-mediated expression of proapoptotic and antiapoptotic proteins in the cerebral cortex of newborn piglets.
Data indicate that Ser738/742-to-glutamate (显示 GRIN2A ELISA试剂盒) protein kinase D (显示 PRKD1 ELISA试剂盒) mutant increased AngII-induced CREB protein and activating transcription factor 2 (显示 ATF2 ELISA试剂盒) phosphorylation, and phospho-CREB binding to the steroidogenic acute regulatory protein (显示 STAR ELISA试剂盒) promoter.
SUMO-1 (显示 SUMO1 ELISA试剂盒) has a role in modifying cAMP-response element-binding protein CREB (显示 CREB ELISA试剂盒) in prolonged hypoxia.
dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB phosphorylation mediated by calcium-independent phospholipase A2 (显示 LYPLA1 ELISA试剂盒)
the p38-MAPK (显示 MAPK14 ELISA试剂盒)/CREB pathway plays a critical role in TNFalpha (显示 TNF ELISA试剂盒)-induced VCAM-1 (显示 VCAM1 ELISA试剂盒) expression
We found several conserved cis elements in the frog CRF genes including a cAMP response element (CRE), activator protein 1 binding sites, and glucocorticoid response elements
p38 MAPK (显示 MAPK14 ELISA试剂盒) and CREB function along the dorsal-ventral axis in mesoderm patterning. The phosphorylated form of CREB (S133) is distributed in a gradient along the dorsal-ventral mesoderm axis and the p38 MAPK (显示 MAPK14 ELISA试剂盒) pathway mediates the phosphorylation of CREB.
modulating CREB activity during early zebrafish development caused significant defects in neural proliferation, midbrain-hindbrain organization and body patterning
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
cAMP responsive element binding protein 1
, cAMP responsive element binding protein
, cyclic AMP-responsive element-binding protein 1
, active transcription factor CREB
, cAMP-response element-binding protein-1
, cAMP-responsive element-binding protein 1
, transactivator protein
, Y protein
, cAMP response element binding protein 1
, cAMP response element-binding protein
, cyclic AMP-responsive element binding protein, delta
, cyclic AMP-responsive DNA-binding protein