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Mouse (Murine) CREB1 ELISA Kit - ABIN832415
Arora, Bhowmik, Khanam, Vohora: Oxcarbazepine and fluoxetine protect against mouse models of obsessive compulsive disorder through modulation of cortical serotonin and CREB pathway. in Behavioural brain research 2013
CREB is positively regulated by PKA and calcium-sensitive calcineurin and negatively by PKC.
The sequence of the CREB gene contains a 88 bp 5 (显示 HSPD1 ELISA试剂盒)' UTR (显示 UTS2R ELISA试剂盒), a 783 bp open reading frame encoding 261 amino acids and a 348 bp 3 (显示 BST1 ELISA试剂盒)' UTR (显示 UTS2R ELISA试剂盒).
Data indicate increasing expression for CREB, ATF1 (显示 AFT1 ELISA试剂盒), and ATF3 (显示 ATF3 ELISA试剂盒) during gastrulation.
GRK3 (显示 ADRBK2 ELISA试剂盒) is a new critical activator of neuroendocrine phenotypes and mediator of CREB activation in promoting neuroendocrine differentiation of prostate cancer cells.
miR (显示 MLXIP ELISA试剂盒)-150 is a novel Wnt (显示 WNT2 ELISA试剂盒) effector that may significantly enhance epithelial-mesenchymal transition of colorectal cancer cells by targeting the CREB signaling pathway
fMRI and genotyping data from a large human sample, together with previous evidence, support the view that CREB1-associated mechanisms modulate brain function and behavior during reward-based decision-making.
Knockdown of either HIF-1 (显示 HIF1A ELISA试剂盒) or CREB or both in hypoxia reduced the expression of hypoxia-response elements- and CRE-mediated gene expression, diminished cell proliferation and increased caspase-3 (显示 CASP3 ELISA试剂盒) activity.
MnTE-2-PyP (显示 PPA1 ELISA试剂盒) decreased p300 (显示 EP300 ELISA试剂盒) complex binding to a specific HRE motif within the PAI-1 (显示 SERPINE1 ELISA试剂盒) gene promoter region, suppressed H3K9 acetylation, and consequently, repressed PAI-1 (显示 SERPINE1 ELISA试剂盒) expression. Mechanistically, less p300 (显示 EP300 ELISA试剂盒) transcriptional complex binding is not due to the reduction of binding between p300 (显示 EP300 ELISA试剂盒) and HIF-1 (显示 HIF1A ELISA试剂盒)/CREB transcription factors, but through inhibiting the binding of HIF-1 (显示 HIF1A ELISA试剂盒)/CREB transcription factors to DNA
Inhibition of CaN attenuated the hTau-induced CREB dephosphorylation with improved synapse and memory functions.
Via blocking the hypoxia-mediated reduction in CREB phosphorylation.
The study adds evidence that CREB, a tumor oncogene (显示 RAB1A ELISA试剂盒), promotes renal cell carcinoma proliferation. It probably achieves this by increasing SKA2 (显示 FAM33A ELISA试剂盒) expression
cigarette smoke extracts activate the PKA, CREB, and IL-13Ralpha2 axis in lung endothelial cells.
This study showed that the induction level of IL-32 (显示 IL32 ELISA试剂盒) was increased in chronic rhinosinusitis with nasal polyps compared to normal nasal mucosa and that LPS (显示 IRF6 ELISA试剂盒)-induced IL-32 (显示 IL32 ELISA试剂盒) expression in nasal polyp-derived fibroblasts was regulated via the TLR4 (显示 TLR4 ELISA试剂盒)/JNK (显示 MAPK8 ELISA试剂盒)/AKT (显示 AKT1 ELISA试剂盒)/CREB signaling pathway.
phosphorylation of CREB is downregulated in the Muller glia.
Data suggest that the upregulation of mitochondrial respiratory chain proteins played a partial role in the protection of PKA/CREB signaling.
Both CREB and deltaFosB play a role in the induction of this behavioural sensitization.
astrocytic IL-17A (显示 IL17A ELISA试剂盒) plays important roles in the maintenance of neuropathic pain through CaMKII (显示 CAMK2G ELISA试剂盒)/CREB signaling pathway in spinal cord.
LH induces MAPK3 (显示 MAPK3 ELISA试剂盒)/1 and Akt (显示 AKT1 ELISA试剂盒) activation, both of which are required for the CREB-promoted expression of EGF (显示 EGF ELISA试剂盒)-like factors in granulosa cells.
However, the mechanism that induces release of IL-6 (显示 IL6 ELISA试剂盒) from skeletal muscle cells remains unknown. Here we show that heat increases IL-6 (显示 IL6 ELISA试剂盒) in skeletal muscle cells through the transient receptor potential vannilloid 1, PKC (显示 PKC ELISA试剂盒), and cAMP response element-binding protein (显示 CREB ELISA试剂盒) signal transduction pathway.
NFIL3 (显示 NFIL3 ELISA试剂盒) functions as an important regulator of glucose homeostasis in the liver by limiting CREB-mediated hepatic gluconeogenesis
EGCG significantly ameliorated insulin (显示 INS ELISA试剂盒) resistance and cognitive disorder by up-regulating the insulin receptor substrate-1 (IRS-1 (显示 IRS1 ELISA试剂盒))/AKT (显示 AKT1 ELISA试剂盒) and ERK (显示 EPHB2 ELISA试剂盒)/cAMP response element binding protein (CREB (显示 CREB ELISA试剂盒))/brain-derived neurotrophic factor (BDNF (显示 BDNF ELISA试剂盒)) signaling pathways.
Ca(2 (显示 CA2 ELISA试剂盒)+) signaling pathway increases Nr4a1 (显示 NR4A1 ELISA试剂盒) expression in MA-10 Leydig cells, at least in part, by enhancing the recruitment of coactivator most likely through the MEF2 (显示 MEF2C ELISA试剂盒), AP1 (显示 JUN ELISA试剂盒), and CREB transcription factors thus demonstrating an important interplay between the Ca(2 (显示 CA2 ELISA试剂盒)+) and cAMP pathways in regulating Nr4a1 (显示 NR4A1 ELISA试剂盒) expression.
PGE2 serves as a central regulator of the Ren (显示 REN1 ELISA试剂盒)-1c gene in the principal cells of the kidney collecting ducts via the PKC (显示 PKC ELISA试剂盒)/cAMP/CREB pathway.
The expression of porcine Prdx6 (显示 PRDX6 ELISA试剂盒) gene is up-regulated by C/EBPbeta (显示 CEBPB ELISA试剂盒) and CREB.
Results suggest that cerebral hypoxia results in differential regulation of CREB protein-mediated expression of proapoptotic and antiapoptotic proteins in the cerebral cortex of newborn piglets.
Data indicate that Ser738/742-to-glutamate (显示 GRIN2A ELISA试剂盒) protein kinase D (显示 PRKD1 ELISA试剂盒) mutant increased AngII-induced CREB protein and activating transcription factor 2 (显示 ATF2 ELISA试剂盒) phosphorylation, and phospho-CREB binding to the steroidogenic acute regulatory protein (显示 STAR ELISA试剂盒) promoter.
SUMO-1 (显示 SUMO1 ELISA试剂盒) has a role in modifying cAMP-response element-binding protein CREB (显示 CREB ELISA试剂盒) in prolonged hypoxia.
dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB phosphorylation mediated by calcium-independent phospholipase A2 (显示 LYPLA1 ELISA试剂盒)
the p38-MAPK (显示 MAPK14 ELISA试剂盒)/CREB pathway plays a critical role in TNFalpha (显示 TNF ELISA试剂盒)-induced VCAM-1 (显示 VCAM1 ELISA试剂盒) expression
We found several conserved cis elements in the frog CRF genes including a cAMP response element (CRE), activator protein 1 binding sites, and glucocorticoid response elements
p38 MAPK (显示 MAPK14 ELISA试剂盒) and CREB function along the dorsal-ventral axis in mesoderm patterning. The phosphorylated form of CREB (S133) is distributed in a gradient along the dorsal-ventral mesoderm axis and the p38 MAPK (显示 MAPK14 ELISA试剂盒) pathway mediates the phosphorylation of CREB.
modulating CREB activity during early zebrafish development caused significant defects in neural proliferation, midbrain-hindbrain organization and body patterning
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
cAMP responsive element binding protein 1
, cAMP responsive element binding protein
, cyclic AMP-responsive element-binding protein 1
, active transcription factor CREB
, cAMP-response element-binding protein-1
, cAMP-responsive element-binding protein 1
, transactivator protein
, Y protein
, cAMP response element binding protein 1
, cAMP response element-binding protein
, cyclic AMP-responsive element binding protein, delta
, cyclic AMP-responsive DNA-binding protein