PCNA (PCNA) ELISA试剂盒产品概述

Full name:
Proliferating Cell Nuclear Antigen ELISA试剂盒 (PCNA)
在www.antibodies-online.cn可供53 Proliferating Cell Nuclear Antigen (PCNA) ELISA试剂盒的14不同的供货商。 再加上,我们可以发PCNA 抗体 (717)PCNA 蛋白 (38)和数多这个蛋白质的别的产品。 总共825 PCNA产品已列进来了。
别名:
53/13, AO090003000846, cb16, CG9193, Dmel\\CG9193, DmPCNA, dPCNA, fb36g03, l(2)02448, l(2)56F, l(2)56Fa, l(2)s1534, Mus209, pcna, pcna-A, Pcna/cyclin, PCNA/mus209, PCNAR, wu:fa28e03, wu:fb36g03

适于 PCNA 相互作用对的更多 ELISA 试剂盒

Fruit Fly (Drosophila melanogaster) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. Results show that regulation of e2f1 and PCNA by DREF in vivo is complex and the regulation mechanism may differ with the tissue and/or positions in the tissue.

  2. crystal of DmPCNA diffracted to 2.0 A resolution and belonged to space group H3, with unit-cell parameters a = b = 151.16, c = 38.28 A

  3. We observed that SUUR chromosomal localization changed along with PCNA pattern and these proteins largely co-localized during the late S-phase in salivary glands.

  4. E2F (显示 E2F2 ELISA试剂盒) regulation of PCNA is dispensable for viability, but is nonetheless important for normal Drosophila development.

  5. A Q123V mutation dramaticly enhances the abilities of Drosophila PCNA to stimulate calf thymus pol delta (显示 POLD1 ELISA试剂盒). Replacing the entire interdomain connector loop AA 119-133 with the corresponding residues from human PCNA results in additional enhancement.

Tomato (Solanum lycopersicum) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. tomato DDI2 gene is required for UV-induced DNA damage repair and plant tolerance to UV stress. [DDI2]

Human Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. Multiple studies provide evidence that PCNA lies at the center of the faithful duplication of eukaryotic genomes and therefore genome integrity. [review]

  2. Human CTF18-RFC clamp-loader complexed with non-synthesising POLE efficiently loads the PCNA sliding clamp.

  3. Results suggest that the UNG2 N-terminus may serve as a flexible scaffold to tether PCNA and RPA at the replication fork, and that post-translational modifications on the UNG2 N-terminus disrupt formation of the PCNA-UNG2-RPA protein complex.

  4. ECRG2 (显示 SPINK7 ELISA试剂盒) in combination with cisplatin (DDP (显示 TIMM8A ELISA试剂盒)) can inhibit viability and induce apoptosis in esophageal cancer DDP (显示 TIMM8A ELISA试剂盒)-resistant cells, possibly via upregulation of p53 (显示 TP53 ELISA试剂盒) expression and downregulation of PCNA expression.

  5. Reduced affinity of PCNA(S228I) for specific clients causes subtle cellular defects in undamaged cells which likely contribute to the etiology of PCNA-associated DNA repair disorder (PARD). Analysis of the binding between PCNA and PCNA-interacting proteins (PIPs (显示 GPRASP1 ELISA试剂盒)) shows that the S228I change dramatically impairs the majority of these interactions, including that of Cdt1 (显示 CDT1 ELISA试剂盒), DNMT1 (显示 DNMT1 ELISA试剂盒), PolD3(p66 (显示 POLD3 ELISA试剂盒)) and PolD4(p12 (显示 POLD4 ELISA试剂盒)).

  6. Data suggest that, during human DNA replication, restricting PCNA (proliferating cell nuclear antigen) to the vicinity of its DNA target site is important; PCNA can be maintained at or near primer/template junctions during DNA synthesis by RPA (显示 RPA1 ELISA试剂盒) (replication protein A) or SSB (single-stranded DNA-binding protein (显示 RPA1 ELISA试剂盒)); here, the SSB used was from Escherichia coli.

  7. Studies demonstrated that POLH (显示 POLH ELISA试剂盒) interaction with PCNA plays an indispensable role in the recruitment of pol-eta to UV-induced cyclobutane pyrimidine dimers site to carry out translesion synthesis (TLS (显示 FUS ELISA试剂盒)), and the dissociation of pol-eta from PCNA after TLS (显示 FUS ELISA试剂盒) is essential for maintaining high fidelity DNA replication.

  8. PCNA is a substrate of the HSV-1 deubiquitinase UL36USP, which has previously been shown to be involved mainly in virus uptake and maturation

  9. Disruption of PCNA-lamins A/C interactions by prelamin A induces DNA replication fork stalling

  10. PCNA plays a critical role in preventing CAG repeat (显示 CELF3 ELISA试剂盒) expansions by modulating the structures of dynamic DNA via cooperation with base excision repair enzymes.

Mouse (Murine) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. work reveals that simulated microgravity promotes the apoptotic response through a combined modulation of the Uev1A/TICAM/TRAF (显示 TRAF1 ELISA试剂盒)/NF-kappaB (显示 NFKB1 ELISA试剂盒)-regulated apoptosis and the p53 (显示 TP53 ELISA试剂盒)/PCNA- and ATM (显示 ATM ELISA试剂盒)/ATR (显示 ATR ELISA试剂盒)-Chk1 (显示 CHEK1 ELISA试剂盒)/2-controlled DNA-damage response pathways.

  2. REV1 promote PCNA monoubiquitylation after UV radiation through interacting with ubiquitylated RAD18 (显示 RAD18 ELISA试剂盒).

  3. PCNA was mainly localized in decidual-stromal cells.

  4. Luteolin may inhibit tumor angiogenesis and tumor cell proliferation by down-regulation of LFA- 3 and PCNA and up-regulation of ICAM-1 (显示 ICAM1 ELISA试剂盒) in tumor tissue of tumor-bearing mice, thereby achieving its anti-tumor effect.

  5. Data suggest Usp1 (ubiquitin specific peptidase 1 (显示 USP1 ELISA试剂盒)) down-regulation by autocleavage is critical for Usp1 (显示 USP1 ELISA试剂盒) to exert role in DNA interstrand crosslink repair; Usp1 (显示 USP1 ELISA试剂盒) role is de-ubiquitination of Pcna and Fancd2 (Fanconi anemia complementation group D2 (显示 FANCD2 ELISA试剂盒)).

  6. The aberrant DNA replication mediated by the PCNA-DNA pol-beta (显示 POLB ELISA试剂盒) complex induces p53 (显示 TP53 ELISA试剂盒)-dependent neuronal cell death

  7. Demonstrate that miR (显示 MLXIP ELISA试剂盒)-376a regulates primordial follicle assembly by modulating the expression of Pcna.

  8. while interaction with PCNA was important for targeting p21 to the CRL4Cdt2 ligase re-localized to MVM replication centers

  9. Styrax japonica glycoprotein increased diethylnitrosamine-induced PCNA activity.

  10. This study identifies a critical role for PCNA in adipose tissue development, and for the first time identifies a role of the core DNA replication machinery at the interface between proliferation and differentiation.

Zebrafish Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. The expression of telomerase activity and TERT (显示 TERT ELISA试剂盒) in retina implies that telomerase has functions other than the elongation of telomere. These findings could provide new insights on telomerase function in the nervous system.

  2. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (显示 CDK1 ELISA试剂盒), wee1 (显示 WEE1 ELISA试剂盒), p21 (显示 CDKN1A ELISA试剂盒), PCNA and cdk2 (显示 CDK2 ELISA试剂盒), but only weakly influences cyclin B1 (显示 CCNB1 ELISA试剂盒), cyclin B2 (显示 CCNB2 ELISA试剂盒) and cyclin E1 (显示 CCNE1 ELISA试剂盒) expression.

Pig (Porcine) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. There is a link between the intestinal detoxification system (CYP1A) & cell renewal system (PCNA). These two processes are inversely correlated in beta-naphthoflavone- exposed fish

Xenopus laevis Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. residue in PCNA that is essential to support destruction of all CRL4(Cdt2) substrates

  2. CRL4Cdt2 ubiquitin ligase directly associates with pcna through its C-terminal domain.

  3. PCNA monoubiquitylation serves as a molecular gas pedal that controls the speed of replisome movement during S phase.

  4. Immunodepletion of Swift PAX-interacting protein 1 (显示 PAXIP1 ELISA试剂盒) from Xenopus extracts prevented efficient PCNA ubiquitination

  5. PCNA docking activates the pre-formed Cdt1-Cul4(DDB1) ligase complex. Thus, PCNA functions as a platform for Cdt1 destruction, ensuring efficient and temporally restricted inactivation of a key cell-cycle regulator.

PCNA 抗原简介

Antigen Summary

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Alternative names and synonyms associated with PCNA

  • mutagen-sensitive 209 (mus209) Elisa Kit
  • proliferating cell nuclear antigen (pcna) Elisa Kit
  • proliferating cell nuclear antigen (pcnA) Elisa Kit
  • proliferating cell nuclear antigen (ANI_1_512014) Elisa Kit
  • proliferating cell nuclear antigen (AOR_1_1500154) Elisa Kit
  • proliferating cell nuclear antigen (PCNA) Elisa Kit
  • proliferating cell nuclear antigen (Pcna) Elisa Kit
  • Proliferating cell nuclear antigen-like (MGC53867) Elisa Kit
  • proliferating cell nuclear antigen-like (LOC100339381) Elisa Kit
  • proliferating cell nuclear antigen1 (pcna1) Elisa Kit
  • 53/13 Elisa Kit
  • AO090003000846 Elisa Kit
  • cb16 Elisa Kit
  • CG9193 Elisa Kit
  • Dmel\\CG9193 Elisa Kit
  • DmPCNA Elisa Kit
  • dPCNA Elisa Kit
  • fb36g03 Elisa Kit
  • l(2)02448 Elisa Kit
  • l(2)56F Elisa Kit
  • l(2)56Fa Elisa Kit
  • l(2)s1534 Elisa Kit
  • Mus209 Elisa Kit
  • pcna Elisa Kit
  • pcna-A Elisa Kit
  • Pcna/cyclin Elisa Kit
  • PCNA/mus209 Elisa Kit
  • PCNAR Elisa Kit
  • wu:fa28e03 Elisa Kit
  • wu:fb36g03 Elisa Kit

Protein level used designations for PCNA

CG9193-PA , CG9193-PB , Proliferating-cell-nuclear-antigen , mus209-PA , mus209-PB , proliferating cell nuclear antigen , proliferating-cell nuclear antigen , DNA polymerase delta auxiliary protein , cyclin , etID36690.10 , fa28e03 , proliferating cell nuclear antigen subtype1 , proliferating cell nuclear antigen subtype2 , proliferating cell nuclear antigen subtype3 , CL1137_1 , CL1137_1(454) , CL1137_1_ov , proliferative cell nuclear antigen

GENE ID SPECIES
37290 Drosophila melanogaster
544248 Solanum lycopersicum
857128 Guillardia theta
2761382 Methanococcus maripaludis S2
4978203 Aspergillus niger CBS 513.88
5788447 Bigelowiella natans
5991960 Aspergillus oryzae RIB40
10447350 Cryptomonas paramecium
5111 Homo sapiens
18538 Mus musculus
25737 Rattus norvegicus
30678 Danio rerio
477166 Canis lupus familiaris
515499 Bos taurus
373984 Gallus gallus
692192 Sus scrofa
100713865 Cavia porcellus
443155 Ovis aries
692356 Bombyx mori
394328 Xenopus laevis
100689335 Cricetulus griseus
398425 Xenopus laevis
100339381 Oryctolagus cuniculus
542425 Zea mays
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