anti-VAV1 (VAV1) 抗体产品概述

Full name:
anti-Vav 1 Oncogene 抗体 (VAV1)
在www.antibodies-online.cn可供169 Vav 1 Oncogene (VAV1) 抗体的23不同的供货商。 再加上,我们可以发VAV1 蛋白 (7)VAV1 试剂盒 (5)和数多这个蛋白质的别的产品。 总共185 VAV1产品已列进来了。
Vav, vav-T

最受欢迎的抗anti-VAV1 (VAV1) 抗体


抗Human VAV1 抗体:

抗Rat (Rattus) VAV1 抗体:

抗Mouse (Murine) VAV1 抗体:

所有可销售的anti-VAV1 抗体


引用最多的anti-VAV1 抗体

  1. Human Polyclonal VAV1 Primary Antibody for WB - ABIN265200 : Moores, Selfors, Fredericks, Breit, Fujikawa, Alt, Brugge, Swat: Vav family proteins couple to diverse cell surface receptors. in Molecular and cellular biology 2000 (PubMed)
    Show all 7 references for 265200

  2. Human Monoclonal VAV1 Primary Antibody for IF, WB - ABIN394445 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for 394445

  3. Human Polyclonal VAV1 Primary Antibody for WB - ABIN196856 : Amarasinghe, Rosen: Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain. in Biochemistry 2005 (PubMed)
    Show all 4 references for 196856

  4. Human Polyclonal VAV1 Primary Antibody for WB - ABIN197374 : Charvet, Canonigo, Billadeau, Altman: Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76. in The Journal of biological chemistry 2005 (PubMed)
    Show all 4 references for 197374

  5. Human Polyclonal VAV1 Primary Antibody for WB - ABIN657774 : Barda-Saad, Shirasu, Pauker, Hassan, Perl, Balbo, Yamaguchi, Houtman, Appella, Schuck, Samelson: Cooperative interactions at the SLP-76 complex are critical for actin polymerization. in The EMBO journal 2010 (PubMed)
    Show all 2 references for 657774

  6. Human Monoclonal VAV1 Primary Antibody for FACS, ELISA - ABIN969581 : Bertagnolo, Nika, Brugnoli, Bonora, Grassilli, Pinton, Capitani: Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells. in Cell and tissue research 2011 (PubMed)
    Show all 2 references for 969581

  7. Cow (Bovine) Polyclonal VAV1 Primary Antibody for WB - ABIN2792554 : Schneider, Rudd: CD28 and Grb-2, relative to Gads or Grap, preferentially co-operate with Vav1 in the activation of NFAT/AP-1 transcription. in Biochemical and biophysical research communications 2008 (PubMed)

  8. Human Polyclonal VAV1 Primary Antibody for IF, ELISA - ABIN1532426 : Ramos-Morales, Romero, Schweighoffer, Bismuth, Camonis, Tortolero, Fischer: The proline-rich region of Vav binds to Grb2 and Grb3-3. in Oncogene 1995 (PubMed)


Human Vav 1 Oncogene (VAV1) interaction partners

  1. Polymorphisms of VAV1 gene is associated with Rheumatoid arthritis.

  2. Vav1 expression is increased in esophageal squamous cell carcinoma, indicates poor prognosis, and can serve as a candidate molecular prognostic marker.

  3. TGFbeta (显示 TGFB1 抗体) induced the dissociation of DNMT1 (显示 DNMT1 抗体) from the VAV1 promoter, leading to demethylation and the subsequent ectopic expression of VAV1 in cancer cells via a SMAD4 (显示 SMAD4 抗体)-dependent mechanism

  4. Our results suggest the existence of a Vav1/PU.1/miR (显示 MLXIP 抗体)-142-3p network that supports all-trans retinoic acid -induced differentiation in acute promyelocytic leukemia (显示 PML 抗体) -derived cells

  5. revealed a new function for Vav1 in the negative feedback regulation of the phosphorylation of immunoreceptor tyrosine-based activation motifs within the zeta chains, CD3 delta (显示 CD3D 抗体), epsilon, gamma chains, as well as activation sites on the critical T cell tyrosine kinases

  6. Data indicate that only a single mutation in the proto-oncogene (显示 RAB1A 抗体) Vav1 enhances tumorigenicity.

  7. These findings establish VAV1 as a critical epigenetically regulated oncogene (显示 RAB1A 抗体) with a key role in MBSHH maintenance, and highlight its potential as a validated therapeutic target and prognostic biomarker for the improved therapy of medulloblastoma.

  8. The present study implies that estrogen-estrogen receptor (显示 ESR1 抗体) modulates the transcription and expression of Vav1, which may contribute to the proliferation of cancerous cells.

  9. The role of Vav1 in T leukemia survival by selectively triggering Rac2 (显示 RAC2 抗体)-Akt (显示 AKT1 抗体) axis and elevating the expression of anti-apoptotic Bcl-2 (显示 BCL2 抗体).

  10. results presented herein suggest a potential cross-talk between cancer cells and the microenvironment controlled by CSF1 (显示 CSF1 抗体)/Vav1 signaling pathways.

Mouse (Murine) Vav 1 Oncogene (VAV1) interaction partners

  1. Vav1 adaptor has a role in the production of inflammatory cytokines by effector T cells and in the susceptibility to neuroinflammation

  2. provide evidence that CD28 (显示 CD28 抗体) and the TCR complex regulate NF-kappaB (显示 NFKB1 抗体) via different signaling modules of GRB-2 (显示 GRB2 抗体)/VAV1 and LAT (显示 LAT 抗体)/ADAP (显示 APP 抗体) pathways respectively.

  3. Platelet P-Rex and Vav family Rac (显示 AKT1 抗体)-GEFs play important proinflammatory roles in leukocyte recruitment.

  4. The data show that vav1 not only affects transcription of the MHCII locus but also is an important regulator of MHCII protein transport to the cell surface.

  5. analyses revealed a SHP2 (显示 PTPN11 抗体)- and Lyn (显示 LYN 抗体)-dependent pathway leading to phosphorylation of Vav1, Rac (显示 AKT1 抗体) activation, and F-actin polymerization in SCF (显示 KITLG 抗体)-treated BMMCs

  6. Data indicate that Vav1 was a key negative regulator of macrophage-derived IL-6 (显示 IL6 抗体) production.

  7. Bruton's Tyrosine Kinase (BTK (显示 BTK 抗体)) and Vav1 contribute to Dectin1 (显示 CLEC7A 抗体)-dependent phagocytosis of Candida albicans in macrophages.

  8. Suggest that Vav1 act as critical molecular link coupling hyperlipidemia with proatherogenic monocyte/macrophage responses.

  9. Loss of Vav1 activity does not favour development of colitis-associated colon cancer.

  10. SH2 and SH3(B) domains of Vav1 are critical for the phosphorylation of Vav1 and its signalling function in TCR-induced calcium flux.

VAV1 抗原简介

Antigen Summary

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with VAV1

  • vav 1 guanine nucleotide exchange factor (VAV1) 抗体
  • vav 1 guanine nucleotide exchange factor (Vav1) 抗体
  • vav 1 oncogene (Vav1) 抗体
  • vav 1 oncogene (vav1) 抗体
  • Vav 抗体
  • vav-T 抗体

Protein level used designations for anti-Vav 1 Oncogene (VAV1) 抗体

vav 1 oncogene , proto-oncogene vav , p95 , p95vav , vav oncogene

455647 Pan troglodytes
7409 Homo sapiens
25156 Rattus norvegicus
485016 Canis lupus familiaris
617345 Bos taurus
100519821 Sus scrofa
22324 Mus musculus
446826 Xenopus laevis
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