PKB (PKB) ELISA试剂盒产品概述

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Protein Kinase B ELISA试剂盒 (PKB)
在www.antibodies-online.cn可供24 Protein Kinase B (PKB) ELISA试剂盒的5不同的供货商。 再加上,我们可以发PKB 抗体 (8)和数多这个蛋白质的别的产品。 总共32 PKB产品已列进来了。
别名:
AKT, CADTK, CAKB, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, PYK2, Rac, RAFTK

适于 PKB 相互作用对的更多 ELISA 试剂盒

Human Protein Kinase B (PKB) interaction partners

  1. Our findings suggest that Pyk2 (显示 PTK2B ELISA试剂盒) plays an important role in the coordination of stabilization of beta-catenin (显示 CTNNB1 ELISA试剂盒) in the crosstalk between Wnt (显示 WNT2 ELISA试剂盒)/beta-catenin (显示 CTNNB1 ELISA试剂盒) and Wnt (显示 WNT2 ELISA试剂盒)/Ca(2 (显示 CA2 ELISA试剂盒)+) signaling pathways upon Wnt3a (显示 WNT3A ELISA试剂盒) stimulation in differentiating hNPCs.

  2. STIM1 (显示 STIM1 ELISA试剂盒)-induced Ca(2 (显示 CA2 ELISA试剂盒)+) signaling activates Pyk2 (显示 PTK2B ELISA试剂盒) to inhibit the interaction of VE-PTP (显示 PTPRB ELISA试剂盒) and VE-cadherin (显示 CDH5 ELISA试剂盒) and hence increase endothelial permeability.

  3. Ascites and CCL18 (显示 CCL18 ELISA试剂盒) stimulate the phosphorylation and expression of Pyk2 (显示 PTK2B ELISA试剂盒), which positively regulates ascites-induced ovarian cancer cell migration.

  4. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin (显示 0 ELISA试剂盒), a process in part mediated through the PI3-kinase (显示 PIK3CA ELISA试剂盒)-Akt/PKB (显示 AKT1 ELISA试剂盒) cell survival pathway. These results provide further rationale for clinical investigation of relaxin (显示 0 ELISA试剂盒) as a potential therapeutic in preeclampsia.

  5. PTK2B polymorphism (rs28834970) could modify the risk of late-onset Alzheimer's disease (LOAD), and PTK2B polymorphism (rs28834970) and APOE may interact to increase LOAD risk in a Han Chinese population.

  6. Studies suggest that PYK2 (显示 PTK2B ELISA试剂盒) is a common downstream effector of ErbB (显示 EGFR ELISA试剂盒) and IL8 (显示 IL8 ELISA试剂盒) receptors, and that PYK2 (显示 PTK2B ELISA试剂盒) integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  7. Pyk2 (显示 PTK2B ELISA试剂盒) is a key downstream signaling molecules of CCR7 (显示 CCR7 ELISA试剂盒) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  8. Phosphoproteomic analysis identifies FAK2 (显示 PTK2B ELISA试剂盒) as a potential therapeutic target for tamoxifen resistance in breast cancer.

  9. Pyk2 (显示 PTK2B ELISA试剂盒)-focal adhesion targeting domain interacts with and binds to leupaxin (显示 LPXN ELISA试剂盒).

  10. Src (显示 SRC ELISA试剂盒) has a role in priming Pyk2 (显示 PTK2B ELISA试剂盒) (but not FAK (显示 PTK2 ELISA试剂盒)) phosphorylation and subsequent activation downstream of integrins

Mouse (Murine) Protein Kinase B (PKB) interaction partners

  1. TSC1 (显示 TSC1 ELISA试剂盒)/TSC2 (显示 TSC2 ELISA试剂盒) complex upregulation of OPN (显示 SPP1 ELISA试剂盒) expression is mediated by transcription factor SOX9 (显示 SOX9 ELISA试剂盒) in an mTOR (显示 FRAP1 ELISA试剂盒)-independent manner. Moreover, ablation of OPN (显示 SPP1 ELISA试剂盒) by deficient TSC1 (显示 TSC1 ELISA试剂盒)/TSC2 (显示 TSC2 ELISA试剂盒) complex contributed to inactivation of AKT (显示 AKT1 ELISA试剂盒) in TSC (显示 SLC12A3 ELISA试剂盒) cells

  2. Our results suggest that increasing Akt (显示 AKT1 ELISA试剂盒)/ NF-kappaB (显示 NFKB1 ELISA试剂盒) is a crucial mediator of skin aging, which can increase the susceptibility of cell transformation.

  3. findings highlight a pivotal link between an epigenetic regulator, WHSC1, and key intracellular signaling molecules, AKT, RICTOR, and Rac1, to drive prostate cancer metastasis.

  4. Studies indicate that the Pten+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten is a key regulatory player in the PI3K/PTEN/AKT (显示 AKT1 ELISA试剂盒) pathway.

  5. a simple, linear, four-compartment ordinary differential equation (ODE) model of Akt (显示 AKT1 ELISA试剂盒) activation that tracks both the biochemical state and the physical location of Akt (显示 AKT1 ELISA试剂盒), is reported.

  6. Psgl-1 (显示 SELPLG ELISA试剂盒) deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT (显示 AKT1 ELISA试剂盒) axis.

  7. Data show that docetaxel, rapamycin and tanespimycin multi-drug loaded micelles targeted against HSP90 (显示 HSP90 ELISA试剂盒) and the PI3K/AKT (显示 AKT1 ELISA试剂盒)/mTOR (显示 FRAP1 ELISA试剂盒) pathway in prostate cancer.

  8. Furthermore, Leishmania RNA virus 1-induced TLR-3 (显示 TLR3 ELISA试剂盒) activation promoted parasite persistence by enhancing macrophage survival through Akt (显示 AKT1 ELISA试剂盒) activation in a manner partially dependent on miR (显示 MLXIP ELISA试剂盒)-155.

  9. Collectively, these findings showed that SA suppressed mammary gland development of pubertal mice, which was coincident with the SA-inhibited HC11 (显示 CCL2 ELISA试剂盒) proliferation, and was associated with inhibition of PI3K/Akt (显示 AKT1 ELISA试剂盒) signaling pathway through activation of GPR120 (显示 O3FAR1 ELISA试剂盒).

  10. Findings suggest that atorvastatin attenuates diabetes-associated renal injury by reducing reactive oxygen species (ROS (显示 ROS1 ELISA试剂盒)) generation, RhoA (显示 RHOA ELISA试剂盒) activity and normalizing Akt (显示 AKT1 ELISA试剂盒)/GSK3beta (显示 GSK3b ELISA试剂盒) signaling pathways.

Pig (Porcine) Protein Kinase B (PKB) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (显示 AKT1 ELISA试剂盒)-mTOR (显示 FRAP1 ELISA试剂盒)-FOXO1 (显示 FOXO1 ELISA试剂盒) signaling and suppressing the activation of TLR4 (显示 TLR4 ELISA试剂盒) and/or NOD2 (显示 NOD2 ELISA试剂盒) signaling pathways.

  2. Data show that homocysteine (Hcy) can ameliorate the endothelium-independent hypoxic coronary vasoconstriction, in which the inhibition of PI3K/Akt (显示 AKT1 ELISA试剂盒) signaling pathway may be involved.

  3. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 (显示 AKT1 ELISA试剂盒) could positively regulate lactose synthesis.

  4. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  5. Host PI3K and Akt1 (显示 AKT1 ELISA试剂盒) play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  6. Activity of AKT (显示 AKT1 ELISA试剂盒) is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  7. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  8. findings show that megalin (显示 LRP2 ELISA试剂盒) is the sensor that determines whether cells will be protected or injured by albumin (显示 ALB ELISA试剂盒); it binds protein kinase B (PKB (显示 AKT1 ELISA试剂盒)) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB (显示 AKT1 ELISA试剂盒) in the luminal plasma membrane [

  9. protein kinase B (PKB/Akt (显示 AKT1 ELISA试剂盒))was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  10. Akt (显示 AKT1 ELISA试剂盒) signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

Goat Protein Kinase B (PKB) interaction partners

  1. Exogenous AKT (显示 AKT1 ELISA试剂盒) was transcribed, and AKT (显示 AKT1 ELISA试剂盒) was overexpressed, inducing the phosphorylation of p70S6K (显示 RPS6KB1 ELISA试剂盒) (Thr389) and 4E-BP1 (显示 EIF4EBP1 ELISA试剂盒) (Thr37/46) in goat fetal fibroblasts.

Cow (Bovine) Protein Kinase B (PKB) interaction partners

  1. These results demonstrate that activation of AKT (显示 AKT1 ELISA试剂盒) is required for gonadotropin regulation of CTNNB1 (显示 CTNNB1 ELISA试剂盒) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (显示 CAV1 ELISA试剂盒) scaffolding domain residue phenylalanine 92 modulates Akt (显示 AKT1 ELISA试剂盒) signaling

  3. TG2 (显示 TGM2 ELISA试剂盒) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT (显示 AKT1 ELISA试剂盒) signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt (显示 AKT1 ELISA试剂盒) activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (显示 GSK3b ELISA试剂盒), and NF-kappaB (显示 NFKB1 ELISA试剂盒).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (显示 NOX1 ELISA试剂盒), reactive oxygen species, and PI3-kinase (显示 PIK3CA ELISA试剂盒) in stimulated NO release.

  6. PI3K/Akt (显示 AKT1 ELISA试剂盒) and p53 (显示 TP53 ELISA试剂盒) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (显示 AKT1 ELISA试剂盒), mTOR (显示 FRAP1 ELISA试剂盒), p70S6K (显示 RPS6KB1 ELISA试剂盒), and ERK1/2 (显示 MAPK1/3 ELISA试剂盒).

  8. Gab1 tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B (显示 AKT1 ELISA试剂盒) and endothelial nitric-oxide synthase (显示 NOS3 ELISA试剂盒) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (显示 NOS3 ELISA试剂盒) phosphorylation and suppresses tumor necrosis factor alpha (显示 TNF ELISA试剂盒)-induced endothelial cell apoptosis by activating AKT1 (显示 AKT1 ELISA试剂盒).

  10. prostaglandin F2alpha phosphorylates TSC2 (显示 TSC2 ELISA试剂盒) and activates mTOR (显示 FRAP1 ELISA试剂盒) and ribosomal protein S6 (显示 RPS6 ELISA试剂盒) kinase (显示 RPS6KB1 ELISA试剂盒) signaling in an AKT (显示 AKT1 ELISA试剂盒)-independent manner

PKB 抗原简介

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PKB

  • protein tyrosine kinase 2 beta (PTK2B) Elisa Kit
  • thymoma viral proto-oncogene 1 (Akt1) Elisa Kit
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) Elisa Kit
  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) Elisa Kit
  • v-akt murine thymoma viral oncogene homolog 2 (AKT2) Elisa Kit
  • AKT Elisa Kit
  • CADTK Elisa Kit
  • CAKB Elisa Kit
  • FADK2 Elisa Kit
  • FAK2 Elisa Kit
  • PKB Elisa Kit
  • PKB/Akt Elisa Kit
  • PKBalpha Elisa Kit
  • PTK Elisa Kit
  • PYK2 Elisa Kit
  • Rac Elisa Kit
  • RAFTK Elisa Kit

Protein level used designations for Protein Kinase B (PKB) ELISA试剂盒

CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , AKT1 kinase , PKB alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1 , RAC-beta serine/threonine-protein kinase

GENE ID SPECIES
2185 Homo sapiens
11651 Mus musculus
24185 Rattus norvegicus
100126861 Sus scrofa
100860904 Capra hircus
280991 Bos taurus
100294652 Ovis aries
449021 Canis lupus familiaris
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