anti-LAT (LAT) 抗体产品概述

Full name:
anti-Linker For Activation of T Cells 抗体 (LAT)
在www.antibodies-online.cn可供289 Linker For Activation of T Cells (LAT) 抗体的26不同的供货商。 再加上,我们可以发LAT 试剂盒 (27)LAT 蛋白 (12)和数多这个蛋白质的别的产品。 总共341 LAT产品已列进来了。
别名:
lat, LAT1, pp36

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引用最多的anti-LAT 抗体

  1. Human Monoclonal LAT Primary Antibody for ICS - ABIN1177079 : Cho, Velikovsky, Swaminathan, Houtman, Samelson, Mariuzza: Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads. in The EMBO journal 2004 (PubMed)
    Show all 6 references for 1177079

  2. Human Monoclonal LAT Primary Antibody for IHC (f), WB - ABIN967609 : Janssen, Zhang: Adaptor proteins in lymphocyte activation. in Current opinion in immunology 2003 (PubMed)
    Show all 6 references for 967609

  3. Human Monoclonal LAT Primary Antibody for IHC (f), WB - ABIN967594 : Lin, Weiss: Identification of the minimal tyrosine residues required for linker for activation of T cell function. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for 967594

  4. Mouse (Murine) Monoclonal LAT Primary Antibody for IF, IP - ABIN238425 : Yamasaki, Ishikawa, Sakuma, Kanagawa, Cheng, Malissen, Saito: LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival. in Molecular and cellular biology 2007 (PubMed)
    Show all 5 references for 238425

  5. Human Monoclonal LAT Primary Antibody for ICS - ABIN1177080 : Paz, Wang, Clarke, Lu, Stokoe, Abo: Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells. in The Biochemical journal 2001 (PubMed)
    Show all 5 references for 1177080

  6. Human Monoclonal LAT Primary Antibody for WB - ABIN393665 : Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010 (PubMed)
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  7. Human Polyclonal LAT Primary Antibody for ELISA, WB - ABIN1533125 : Zhang, Sloan-Lancaster, Kitchen, Trible, Samelson: LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. in Cell 1998 (PubMed)
    Show all 2 references for 1533125

  8. Human Polyclonal LAT Primary Antibody for ELISA, WB - ABIN250250 : Finco, Kadlecek, Zhang, Samelson, Weiss: LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. in Immunity 1998 (PubMed)

更多抗LAT的相互作用对抗体

Human Linker For Activation of T Cells (LAT) interaction partners

  1. LAT (显示 ORC3 抗体) and SLP-76 (显示 LCP2 抗体) are randomly dispersed throughout the clusters that form upon T cell receptor engagement.

  2. this study shows that inherited LAT (显示 ORC3 抗体) deficiency should be considered in patients with combined immunodeficiency with T-cell abnormalities

  3. This is the first report of a LAT (显示 ORC3 抗体)-related disease in humans, manifesting by a progressive combined immune deficiency with severe autoimmune disease.

  4. Data show that LAT1 plays an important role in regulating the uptake of essential amino acids such as leucine into endometrial cancer cells. Increased ability of BCH (显示 CHN2 抗体) compared to LAT1 shRNA at inhibiting Ishikawa spheroid area suggests that other LAT (显示 ORC3 抗体) family members may also contribute to cell growth.

  5. Data indicate that the T cell-specific adaptor protein (TSAd (显示 SH2D2A 抗体)) SH2 domain interacts with CD6 antigen (显示 CD6 抗体) and linker for activation of T cells protein (LAT (显示 ORC3 抗体)) phosphotyrosine (pTyr) peptides.

  6. High expression of LAT1 and ASCT2 (显示 SLC1A5 抗体) correlates with metastasis and invasion in esophageal squamous cell carcinoma.

  7. IFT20 (显示 IFT20 抗体) is required for the delivery of the intracellular pool of LAT (显示 ORC3 抗体) to the immune synapse in naive primary T lymphocytes.

  8. Data show that the palmitoylation mutation of linker for activation of T cells (LAT)attenuated the signal transduction induced by glycosylphosphatidylinositol-anchored CD59 antigen (显示 CD59 抗体) in T cells.

  9. HSV-1-encoded Us3 protein interrupted TCR signaling and interleukin-2 (显示 IL2 抗体) production by inactivation of the linker for activation of T cells.

  10. Patients with severe aplastic anemia had increased levels of LAT (显示 ORC3 抗体) and disturbed Th1 (显示 TH1L 抗体)-Th2 balance.

Mouse (Murine) Linker For Activation of T Cells (LAT) interaction partners

  1. this study shows that the site-specific delivery of linker for activation of T cells (LAT) in asthmatic mouse model

  2. IFT20 (显示 IFT20 抗体) is required for the delivery of the intracellular pool of LAT to the immune synapse in naive primary T lymphocytes.

  3. miR (显示 MLXIP 抗体)-155 regulates the delicate balance between PAK1 (显示 PAK1 抗体)-mediated proliferation and apoptosis in T cells impacting lymphoid organ size and function.

  4. provide evidence that CD28 (显示 CD28 抗体) and the TCR complex regulate NF-kappaB (显示 NFKB1 抗体) via different signaling modules of GRB-2 (显示 GRB2 抗体)/VAV1 (显示 VAV1 抗体) and LAT/ADAP (显示 APP 抗体) pathways respectively.

  5. The result indicate that LAT-PLCg1 (显示 PLCG1 抗体) interaction is important for controlling IL-6 (显示 IL6 抗体) production by T cells and demonstrate a critical role of IL-6 (显示 IL6 抗体) in the development of the lymphoproliferative syndrome.

  6. low level of LAT-PLC-gamma1 (显示 PLCG1 抗体) interaction was associated with Th2 polarized differentiation, and this may contribute to the etiology of asthma.

  7. These results suggest that proteasome-mediated degradation is involved in hypophosphorylated LAT and PLCgamma1 (显示 PLCG1 抗体) in Dow2-induced anergic T cells. The novel CD3 (显示 CD3E 抗体)-specific Ab, Dow2, may provide us with a unique tool for inducing immunosuppression

  8. Sos1 (显示 SOS1 抗体) has distinct roles in acting as a scaffold to oligomerize the adaptor protein LAT, and in guanine nucleotide exchange activity

  9. this analysis identified 65 proteins not associated before with the Zap70 (显示 ZAP70 抗体)-Lat-SLP-76 (显示 LCP2 抗体) network and thus should provide cues for future functional experiments.

  10. Data suggest that transmembrane adaptor protein LAT-PLCgamma1 (Phospholipase C gamma 1 (显示 PLCG1 抗体)) signaling may function differently in various subsets of gammadelta T cells.

LAT 抗原简介

Antigen Summary

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with LAT

  • linker for activation of T cells (LAT) 抗体
  • linker for activation of T cells (lat) 抗体
  • linker for activation of T cells (Lat) 抗体
  • lat 抗体
  • LAT1 抗体
  • pp36 抗体

Protein level used designations for LAT

linker for activation of T cells , 36 kDa phospho-tyrosine adapter protein , 36 kDa phospho-tyrosine adaptor protein , linker for activation of T cells, transmembrane adaptor , linker for activation of T-cells family member 1 , p36-38 , pp36 , linker protein

GENE ID SPECIES
704656 Macaca mulatta
743295 Pan troglodytes
100233211 Danio rerio
27040 Homo sapiens
81511 Rattus norvegicus
16797 Mus musculus
514735 Bos taurus
607947 Canis lupus familiaris
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