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INPP5D 抗体

(Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
INPP5D 抗体  (AA 959-1188) INPP5D 抗体  (AA 959-1188) INPP5D 抗体 (AA 959-1188) (ABIN6213625)

INPP5D 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

INPP5D 抗体 INPP5D 抗体 INPP5D 抗体 (ABIN7267882)

INPP5D 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

Recombinant INPP5D 抗体 Recombinant INPP5D 抗体 Recombinant INPP5D 抗体 (ABIN7127806)

INPP5D 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Monoclonal 9G11 unconjugated Recombinant Antibody

INPP5D 抗体 by 适用

Find INPP5D 抗体 for a variety of species such as anti-Human INPP5D, anti-Mouse INPP5D, anti-Rat INPP5D. The species listed below are among those available. Click on a link to go to the corresponding products.

INPP5D 抗体 by 应用范围

Find INPP5D 抗体 validated for a specific application such as WB, ELISA, FACS, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

INPP5D 抗体 by 抗体来源

Find INPP5D 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

INPP5D 抗体 by 抗原表位

Find INPP5D 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

INPP5D 抗体 by 克隆形成能力

Find available monoclonal or polyclonal INPP5D 抗体. Click on a link to go to the corresponding products.

INPP5D 抗体 by 克隆

Find INPP5D 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

INPP5D 抗体 by 标记

Find INPP5D 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular INPP5D 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6213625
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7267882
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (3)
Cat. No. ABIN7127806
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6265066
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7182682
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC
Validations
  • (2)
Cat. No. ABIN7249698
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3182231
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN302081
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7185528
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN3186950
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6747482
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6136110
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rabbit, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN5774318
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse
Application WB, ELISA, FACS
Validations
Cat. No. ABIN745733
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse
Application WB, ELISA
Validations
Cat. No. ABIN700915
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our INPP5D 抗体

Sácha, Zámecník, Barinka, Hlouchová, Vícha, Mlcochová, Hilgert, Eckschlager, Konvalinka: "Expression of glutamate carboxypeptidase II in human brain." in: Neuroscience, Vol. 144, Issue 4, pp. 1361-72, (2007) (PubMed).

Rovenská, Hlouchová, Sácha, Mlcochová, Horák, Zámecník, Barinka, Konvalinka: "Tissue expression and enzymologic characterization of human prostate specific membrane antigen and its rat and pig orthologs." in: The Prostate, Vol. 68, Issue 2, pp. 171-82, (2007) (PubMed).

Mesters, Barinka, Li, Tsukamoto, Majer, Slusher, Konvalinka, Hilgenfeld: "Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer." in: The EMBO journal, Vol. 25, Issue 6, pp. 1375-84, (2006) (PubMed).

Rotblat, Yizhar, Haklai, Ashery, Kloog: "Ras and its signals diffuse through the cell on randomly moving nanoparticles." in: Cancer research, Vol. 66, Issue 4, pp. 1974-81, (2006) (PubMed).

Roy, Plowman, Rotblat, Prior, Muncke, Grainger, Parton, Henis, Kloog, Hancock: "Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling." in: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6722-33, (2005) (PubMed).

Maxwell, Yuan, Anderson, Hibbs, Salem, Jackson: "SHIP1 and Lyn Kinase Negatively Regulate Integrin alpha IIb beta 3 signaling in platelets." in: The Journal of biological chemistry, Vol. 279, Issue 31, pp. 32196-204, (2004) (PubMed).

Rotblat, Prior, Muncke, Parton, Kloog, Henis, Hancock: "Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane." in: Molecular and cellular biology, Vol. 24, Issue 15, pp. 6799-810, (2004) (PubMed).

Giuriato, Pesesse, Bodin, Sasaki, Viala, Marion, Penninger, Schurmans, Erneux, Payrastre: "SH2-containing inositol 5-phosphatases 1 and 2 in blood platelets: their interactions and roles in the control of phosphatidylinositol 3,4,5-trisphosphate levels." in: The Biochemical journal, Vol. 376, Issue Pt 1, pp. 199-207, (2003) (PubMed).

Jiang, Stuible, Chalandon, Li, Chan, Eisterer, Krystal, Eaves, Eaves: "Evidence for a positive role of SHIP in the BCR-ABL-mediated transformation of primitive murine hematopoietic cells and in human chronic myeloid leukemia." in: Blood, Vol. 102, Issue 8, pp. 2976-84, (2003) (PubMed).

Sly, Rauh, Kalesnikoff, Büchse, Krystal: "SHIP, SHIP2, and PTEN activities are regulated in vivo by modulation of their protein levels: SHIP is up-regulated in macrophages and mast cells by lipopolysaccharide." in: Experimental hematology, Vol. 31, Issue 12, pp. 1170-81, (2003) (PubMed).

Aliases for INPP5D 抗体

inositol polyphosphate-5-phosphatase D (INPP5D) 抗体
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100446045) 抗体
inositol polyphosphate-5-phosphatase D (inpp5d) 抗体
inositol polyphosphate 5-phosphatase (EHI_159880) 抗体
inositol polyphosphate 5-phosphatase (EHI_153490) 抗体
inositol polyphosphate-5-phosphatase D L homeolog (inpp5d.L) 抗体
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100380693) 抗体
inositol polyphosphate-5-phosphatase D (Inpp5d) 抗体
13.t00027 抗体
256.t00004 抗体
AI323613 抗体
hp51CN 抗体
INPP5D 抗体
s-SHIP 抗体
ship 抗体
SHIP 抗体
SHIP-1 抗体
ship1 抗体
SHIP1 抗体
SIP-145 抗体
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