anti-人 IL17A 抗体 for Neutralization

Recommended IL17A Antibody (supplied by: Log in to see )

抗原
Interleukin 17A (IL17A) 抗体
  • Il17
  • IL17A
  • CTLA8
  • IL-17
  • IL-17A
  • IL17
  • Ctla-8
  • Ctla8
  • CTLA-8
  • ChIL-17
  • IL-17F
  • interleukin 17A
  • interleukin 17A-like
  • interleukin 17F
  • Il17a
  • IL17A
  • LOC100339322
  • IL17F
抗原表位
AA 20-155
54
24
22
13
12
11
9
7
7
6
4
4
3
3
2
2
1
1
1
1
1
1
适用

401
145
41
7
7
5
3
3
2
2
宿主
山羊
275
134
86
43
3
3
克隆类型
多克隆
标记
This IL17A antibody is un-conjugated
56
36
27
21
20
19
18
15
14
14
10
7
7
7
7
7
7
7
7
5
5
5
4
4
4
3
2
2
2
应用范围
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Neutralization (Neut), Western Blotting (WB)
273
234
229
44
31
20
19
16
11
10
8
8
7
6
6
4
4
4
3
3
2
1
1
1
1
1
1
1
Supplier
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产品编号 ABIN4900592
产品在该地区无法提供。
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN4324658 BP FACS Neut WB Mouse IgG2b kappa Log in to see 4H1524 2
1 ABIN5551704 EIA Neut WB Rabbit IgG Log in to see Polyclonal
1 ABIN1686096 Neut IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1686097 Neut ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN4324655 BP CyTOF FACS Neut WB Mouse IgG2b kappa Log in to see 4H1524
1 ABIN1102463 IHC (p) Neut ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN5633996 CyTOF FACS ICC IHC IP Neut WB Goat IgG AA 20-155 Log in to see Polyclonal
1 ABIN465126 IHC Neut ELISA WB Goat Log in to see Polyclonal
1 ABIN2692379 Neut Mouse IgG1 AA 20-155 Log in to see M237
1 ABIN181572 EIA IHC (p) Neut WB Goat Log in to see Polyclonal
1 ABIN464998 ELISA IHC Neut WB Biotin Goat Log in to see Polyclonal
1 ABIN786714 Neut Mouse IgG1 Log in to see 403D10-01 6
1 ABIN290358 ICC FACS Neut ELISA WB Goat IgG Log in to see Polyclonal
1 ABIN4324657 BP FACS Neut WB Mouse IgG2b kappa Log in to see 4H1524
1 ABIN2472055 Neut ELISA WB Biotin Mouse IgG2b, kappa full length Log in to see Polyclonal
1 ABIN2451283 Neut IHC ELISA Rabbit IgG Log in to see Polyclonal
1 ABIN2472054 Neut ELISA WB Mouse IgG2b, kappa full length Log in to see Polyclonal
1 ABIN786712 Neut Biotin Mouse IgG1 Log in to see 403D10-01 6
1 ABIN786727 ELISA (Capture) FACS Neut Mouse IgG2a Log in to see 408H6-01
1 ABIN786724 ELISA (Detection) Neut Mouse IgG1 Log in to see 414A11-03

General

抗原 Interleukin 17A (IL17A) 抗体
抗原表位 AA 20-155
(54), (24), (22), (13), (12), (11), (9), (7), (7), (6), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
适用
(401), (145), (41), (7), (7), (5), (3), (3), (2), (2)
宿主 山羊
(275), (134), (86), (43), (3), (3)
克隆类型
多克隆
标记 This IL17A antibody is un-conjugated
(56), (36), (27), (21), (20), (19), (18), (15), (14), (14), (10), (7), (7), (7), (7), (7), (7), (7), (7), (5), (5), (5), (4), (4), (4), (3), (2), (2), (2)
应用范围 Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Neutralization (Neut), Western Blotting (WB)
(273), (234), (229), (44), (31), (20), (19), (16), (11), (10), (8), (8), (7), (6), (6), (4), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 20个引用可参考
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IL17A抗体详情

IL17A目标详情 使用细节 贮存及处理 References for anti-IL17A antibody (ABIN4900592) 图像
特异性 Detects human IL-17 in direct ELISAs and Western blots. In direct ELISAs, approximately 60 % cross-reactivity with recombinant canine IL-17 is observed, approximately 10 % cross-reactivity with recombinant human (rh) IL-17F and with recombinant mouse IL-17 is observed, and less than 1 % cross-reactivity with rhIL-17B, rhIL-17C, rhIL-17D, and rhIL-17E is observed.
纯化方法 Antigen Affinity-purified
过滤 0.2 μm filtered
内毒素水平 <0.10 EU per 1 μg of the antibody by the LAL method.
免疫原 E. coli-derived recombinant human IL-17, Ile20-Ala155, Accession # Q16552
亚型 IgG

IL17A目标详情

IL17A抗体详情 使用细节 贮存及处理 References for anti-IL17A antibody (ABIN4900592) 图像 回页首
抗原
别名 IL-17/IL-17A (IL17A Antibody 摘要)
背景 Alternative Names: CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, IL17interleukin-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A
基因ID 3605
UniProt Q16552

使用细节

IL17A抗体详情 IL17A目标详情 贮存及处理 References for anti-IL17A antibody (ABIN4900592) 图像 回页首
应用备注 Western Blot 1 μg/mL
Immunohistochemistry 1-15 μg/mL
Immunoprecipitation 3 μg/100 μg cell lysate
Neutralization 0.02-0.12 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
Immunocytochemistry 5-15 μg/mL
CyTOF-ready
限制 仅限研究用

贮存及处理

IL17A抗体详情 IL17A目标详情 使用细节 References for anti-IL17A antibody (ABIN4900592) 图像 回页首
溶解方式 Reconstitute at 0.2 mg/mL in sterile PBS.
缓冲液 Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
储存液 Without preservative
储存条件 4 °C,-20 °C,-80 °C
储存方法 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
有效期 12 months

References for anti-IL17A antibody (ABIN4900592)

IL17A抗体详情 IL17A目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Millar, Akbar, Campbell, Reilly, Kerr, McLean, Frleta-Gilchrist, Fazzi, Leach, Rooney, Crowe, Murrell, McInnes: "IL-17A mediates inflammatory and tissue remodelling events in early human tendinopathy." in: Scientific reports, Vol. 6, pp. 27149, 2016 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Fattahi, Brandsma, Lodewijk, Reinders-Luinge, Postma, Timens, Hylkema, Ten Hacken: "Atopy and Inhaled Corticosteroid Use Associate with Fewer IL-17+ Cells in Asthmatic Airways." in: PLoS ONE, Vol. 11, Issue 8, pp. e0161433, 2016 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Mariuzzi, Domenis, Orsaria, Marzinotto, Londero, Bulfoni, Candotti, Zanello, Ballico, Mimmi, Calcagno, Marchesoni, Di Loreto, Beltrami, Cesselli, Gri: "Functional expression of aryl hydrocarbon receptor on mast cells populating human endometriotic tissues." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 96, Issue 9, pp. 959-71, 2016 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Nussbaumer-Ochsner, Stolk, Ferraz da Silva, van Schadewijk, de Jeu, Prins, Mauad, Rabe, Hiemstra: "Association of Lung Inflammatory Cells with Small Airways Function and Exhaled Breath Markers in Smokers - Is There a Specific Role for Mast Cells?" in: PLoS ONE, Vol. 10, Issue 6, pp. e0129426, 2015 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Martin, Kesselring, Saidou, Brunner, Schiechl, Mouris, Wege, Rümmele, Schlitt, Geissler, Fichtner-Feigl: "RORγt(+) hematopoietic cells are necessary for tumor cell proliferation during colitis-associated tumorigenesis in mice." in: European journal of immunology, Vol. 45, Issue 6, pp. 1667-79, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Punt, Houwing-Duistermaat, Schulkens, Thijssen, Osse, de Kroon, Griffioen, Fleuren, Gorter, Jordanova: "Correlations between immune response and vascularization qRT-PCR gene expression clusters in squamous cervical cancer." in: Molecular cancer, Vol. 14, pp. 71, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Chang, Al-Alwan, Alshakfa, Audusseau, Mogas, Chouiali, Nair, Baglole, Hamid, Eidelman: "Upregulation of IL-17A/F from human lung tissue explants with cigarette smoke exposure: implications for COPD." in: Respiratory research, Vol. 15, pp. 145, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Liu, Jin, Zhang, Lin, Chen, Sun, Zhang, Zhang, Yu: "Intratumor IL-17-positive mast cells are the major source of the IL-17 that is predictive of survival in gastric cancer patients." in: PLoS ONE, Vol. 9, Issue 9, pp. e106834, 2014 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Keijsers, Hendriks, van Erp, van Cranenbroek, van de Kerkhof, Koenen, Joosten: "In vivo induction of cutaneous inflammation results in the accumulation of extracellular trap-forming neutrophils expressing RORγt and IL-17." in: The Journal of investigative dermatology, Vol. 134, Issue 5, pp. 1276-84, 2014 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Hendriks, van der Velden, Wolberink, Seyger, Schalkwijk, Zeeuwen, de Jong, Pasch, van Erp, van de Kerkhof: "The effect of adalimumab on key drivers in the pathogenesis of psoriasis." in: The British journal of dermatology, Vol. 170, Issue 3, pp. 571-80, 2014 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Shimizu, Tasaki, Sano, Ju, Nishihara, Oishi, Koga, Kawai, Kanda: "Sera from remitting and secondary progressive multiple sclerosis patients disrupt the blood-brain barrier." in: PLoS ONE, Vol. 9, Issue 3, pp. e92872, 2014 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Todd, Simpson, Estis, Torres, Wub: "Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays." in: Cytokine, Vol. 64, Issue 3, pp. 660-5, 2013 Method employed by authors: ELISA (ELISA) (Sample species: Human).

Lotti, Jarrar, Pai, Hitomi, Lathia, Mace, Gantt, Sukhdeo, DeVecchio, Vasanji, Leahy, Hjelmeland, Kalady, Rich: "Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A." in: The Journal of experimental medicine, Vol. 210, Issue 13, pp. 2851-72, 2013 Method employed by authors: Immunofluorescence (IF) (Sample species: Human).

Truchetet, Brembilla, Montanari, Lonati, Raschi, Zeni, Fontao, Meroni, Chizzolini: "Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement." in: Arthritis and rheumatism, Vol. 65, Issue 5, pp. 1347-56, 2013 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Xing, Yang, Yang, Wei, Zhu, Gao, Li: "IL-17A induces endothelial inflammation in systemic sclerosis via the ERK signaling pathway." in: PLoS ONE, Vol. 8, Issue 12, pp. e85032, 2013 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Gelderblom, Weymar, Bernreuther, Velden, Arunachalam, Steinbach, Orthey, Arumugam, Leypoldt, Simova, Thom, Friese, Prinz, Hölscher, Glatzel, Korn, Gerloff, Tolosa, Magnus: "Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke." in: Blood, Vol. 120, Issue 18, pp. 3793-802, 2012 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Fontao, Brembilla, Masouyé, Kaya, Prins, Dupin, Saurat, Chizzolini, Piguet: "Interleukin-17 expression in neutrophils and Th17 cells in cutaneous T-cell lymphoma associated with neutrophilic infiltrate of the skin." in: The British journal of dermatology, Vol. 166, Issue 3, pp. 687-9, 2012 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Droeser, Zlobec, Kilic, Güth, Heberer, Spagnoli, Oertli, Tapia: "Differential pattern and prognostic significance of CD4+, FOXP3+ and IL-17+ tumor infiltrating lymphocytes in ductal and lobular breast cancers." in: BMC cancer, Vol. 12, pp. 134, 2012 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Liu, Lee, McManus, Choy: "Induction of endothelial nitric oxide synthase expression by IL-17 in human vascular endothelial cells: implications for vascular remodeling in transplant vasculopathy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 3, pp. 1544-50, 2012 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Lapinski, Kwon, Lubeck, Wilkinson, Srinivasan, Sevick-Muraca, King: "RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice." in: The Journal of clinical investigation, Vol. 122, Issue 2, pp. 733-47, 2012 Method employed by authors: Neutralization (Neut) (Sample species: Human).

图像

IL17A抗体详情 IL17A目标详情 使用细节 贮存及处理 References for anti-IL17A antibody (ABIN4900592) 回页首
厂商提供的图像
Neutralization (Neut) image for anti-Interleukin 17A (IL17A) (AA 20-155) antibody (ABIN4900592) IL-6 Secretion Induced by IL-17 and Neutralization by Human IL-17 Antibody.
Flow Cytometry (FACS) image for anti-Interleukin 17A (IL17A) (AA 20-155) antibody (ABIN4900592) Detection of IL-17 in Human PBMCs by Flow Cytometry.
Immunohistochemistry (IHC) image for anti-Interleukin 17A (IL17A) (AA 20-155) antibody (ABIN4900592) IL-17/IL-17A in Human Tonsil. IL-17/IL-17A was detected in immersion fixed paraffin-e...
Immunoprecipitation (IP) image for anti-Interleukin 17A (IL17A) (AA 20-155) antibody (ABIN4900592) Immunoprecipitation of Human IL-17.
Western Blotting (WB) image for anti-Interleukin 17A (IL17A) (AA 20-155) antibody (ABIN4900592) Detection of Human IL-17 by Western Blot.
Western Blotting (WB) image for anti-Interleukin 17A (IL17A) (AA 20-155) antibody (ABIN4900592) Detection of Human IL-17 by Western Blot.
Flow Cytometry (FACS) image for anti-Interleukin 17A (IL17A) (AA 20-155) antibody (ABIN4900592) Detection of IL-17 in Human PBMCs by Flow Cytometry.
Immunohistochemistry (IHC) image for anti-Interleukin 17A (IL17A) (AA 20-155) antibody (ABIN4900592) IL-17/IL-17A in Human Tonsil. IL-17/IL-17A was detected in immersion fixed paraffin-e...
Neutralization (Neut) image for anti-Interleukin 17A (IL17A) (AA 20-155) antibody (ABIN4900592) IL-6 Secretion Induced by IL-17 and Neutralization by Human IL-17 Antibody.
Immunoprecipitation (IP) image for anti-Interleukin 17A (IL17A) (AA 20-155) antibody (ABIN4900592) Immunoprecipitation of Human IL-17.