anti-猕猴 CD28 抗体 for Flow Cytometry

Recommended CD28 Antibody (supplied by: Log in to see )

抗原
CD28 抗体
  • Tp44
  • CD28RNA
  • cd28
  • CD28 molecule
  • CD28 antigen
  • Cd28 molecule
  • CD28 molecule L homeolog
  • CD28
  • Cd28
  • cd28.L
适用
Baboon, Cynomolgus, 猕猴
496
414
103
70
67
42
41
34
27
23
15
7
3
3
3
1
1
宿主
小鼠
526
203
92
70
40
29
12
1
克隆类型
单克隆
标记
This CD28 antibody is un-conjugated
113
96
74
56
21
20
20
19
17
17
13
13
13
13
12
12
12
8
8
6
6
6
6
6
5
4
3
3
2
2
2
2
2
2
2
2
1
应用范围
Flow Cytometry (FACS)
787
211
185
160
143
141
133
129
89
77
26
19
13
9
8
6
4
3
3
3
3
2
2
2
1
1
1
1
1
1
选项
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产品编号 ABIN2689147
产品在该地区无法提供。

General

抗原 CD28 抗体
适用 Baboon, Cynomolgus, 猕猴
(496), (414), (103), (70), (67), (42), (41), (34), (27), (23), (15), (7), (3), (3), (3), (1), (1)
宿主 小鼠
(526), (203), (92), (70), (40), (29), (12), (1)
克隆类型 (克隆位点)
单克隆   ( )
标记 This CD28 antibody is un-conjugated
(113), (96), (74), (56), (21), (20), (20), (19), (17), (17), (13), (13), (13), (13), (12), (12), (12), (8), (8), (6), (6), (6), (6), (6), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1)
应用范围 Flow Cytometry (FACS)
(787), (211), (185), (160), (143), (141), (133), (129), (89), (77), (26), (19), (13), (9), (8), (6), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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CD28抗体详情

CD28目标详情 使用细节 贮存及处理 图像
品牌 BD Pharmingen™
产品特性 The CD28.2 monoclonal antibody specifically binds to CD28, a 44 kDa homodimeric transmembrane glycoprotein present on most mature T cells, thymocytes and plasma cells. CD28 is a costimulatory receptor that binds CD80 and CD86 as ligands and plays a very important role in T cell-B cell interactions. It has been suggested that CD28 initiates and regulates a separate and distinct signal transduction pathway from those stimulated by the TCR complex. Additionally, it has been reported that CD28 antibody clones vary in their ability to stimulate T cells to produce IL-2 and increase intracellular Ca2+ concentration. This finding suggests the existence of functionally distinct subregions on the CD28 Molecule. CD28.2 has been demonstrated to bind to the same molecule as clone L293, another CD28 mAb, and has been reported to induce Ca2+ influx in Jurkat T cells. This clone also cross-reacts with a subset of peripheral blood lymphocytes, but not monocytes or granulocytes, of baboon, rhesus and cynomolgus macaques. The distribution on lymphocytes is similar to that observed with normal human donor lymphocytes, however, as described in the literature, the frequency of CD28.2-positive lymphocytes is reduced in the non-human primate, with the majority of cells being CD28 negative. Profile of anti-CD28 reactivity on peripheral blood lymphocytes of Rhesus macaque (macaca mulatta) analyzed by flow cytometry.

BD Pharmingen™ Purified Mouse Anti-Human CD28 - Purified - Clone CD28.2 - Isotype Mouse IgG1, κ - Reactivity Bab, Cyno, Rhe - 0.1 mg
纯化方法 The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
免疫原 Human CD28 Transfected Cell Line
克隆位点 CD28-2
亚型 IgG1, kappa

CD28目标详情

CD28抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 CD28 (CD28 Antibody 摘要)
背景 Synonyms: CD28 antigen, T44, Tp44, TP44
研究领域 Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis
途径 TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

使用细节

CD28抗体详情 CD28目标详情 贮存及处理 图像 回页首
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用

贮存及处理

CD28抗体详情 CD28目标详情 使用细节 图像 回页首
浓度 0.5 mg/mL
缓冲液 Aqueous buffered solution containing ≤0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C
储存方法 Store undiluted at 4°C.