beta-2 Microglobulin 蛋白 (B2M)产品概述

Full name:
beta-2-Microglobulin 蛋白 (B2M)
在www.antibodies-online.cn可供126 beta-2-Microglobulin (B2M) 蛋白的17不同的供货商。 再加上,我们可以发beta-2 Microglobulin 抗体 (749)beta-2 Microglobulin 试剂盒 (85)和数多这个蛋白质的别的产品。 总共976 beta-2 Microglobulin产品已列进来了。
别名:
b2m, b2m-W01, b2m-W03, b2m-Z01, b2m-Z02, b2m-Z03, B2MG, beta2-m, beta2m, bwm, Ly-m11, wu:fa94c05, wu:fb10a09
列出全部蛋白 基因 基因ID UniProt
大鼠 B2M B2M 24223 P07151
小鼠 B2M B2M 12010 P01887
B2M 567 P61769

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引用最多的beta-2 Microglobulin 蛋白

  1. Rat (Rattus) beta-2 Microglobulin Protein expressed in HEK-293 Cells - ABIN2180615 : Gorevic, Munoz, Casey, DiRaimondo, Stone, Prelli, Rodrigues, Poulik, Frangione: Polymerization of intact beta 2-microglobulin in tissue causes amyloidosis in patients on chronic hemodialysis. in Proceedings of the National Academy of Sciences of the United States of America 1986 (PubMed)
    Show all 5 references for 2180615

  2. Cynomolgus beta-2 Microglobulin Protein expressed in HEK-293 Cells - ABIN2180610 : Argilés, Derancourt, Jauregui-Adell, Mion, Demaille: Biochemical characterization of serum and urinary beta 2 microglobulin in end-stage renal disease patients. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1993 (PubMed)
    Show all 5 references for 2180610

  3. Human beta-2 Microglobulin Protein expressed in HEK-293 Cells - ABIN2180612 : Momoi, Suzuki, Titani, Hisanaga, Ogawa, Saito: Amino acid sequence of a modified beta 2-microglobulin in renal failure patient urine and long-term dialysis patient blood. in Clinica chimica acta; international journal of clinical chemistry 1995 (PubMed)
    Show all 5 references for 2180612

  4. Cynomolgus beta-2 Microglobulin Protein expressed in Human Cells - ABIN2009919 : Miyata, Inagi, Wada, Ueda, Iida, Takahashi, Taniguchi, Maeda: Glycation of human beta 2-microglobulin in patients with hemodialysis-associated amyloidosis: identification of the glycated sites. in Biochemistry 1994 (PubMed)
    Show all 4 references for 2009919

  5. Rat (Rattus) beta-2 Microglobulin Protein expressed in Human Cells - ABIN2009601 : Trinh, Smith, Kalverda, Phillips, Radford: Crystal structure of monomeric human beta-2-microglobulin reveals clues to its amyloidogenic properties. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 4 references for 2009601

  6. Mouse (Murine) beta-2 Microglobulin Protein expressed in Human Cells - ABIN2008449 : He, Xu, Liu, Zeng: [Cloning of human beta-microglobulin gene and its high expression in Escherichia coli]. in Sheng wu gong cheng xue bao = Chinese journal of biotechnology 2005 (PubMed)
    Show all 4 references for 2008449

  7. Human beta-2 Microglobulin Protein expressed in Human Cells - ABIN2004946 : Kihara, Chatani, Iwata, Yamamoto, Matsuura, Nakagawa, Naiki, Goto: Conformation of amyloid fibrils of beta2-microglobulin probed by tryptophan mutagenesis. in The Journal of biological chemistry 2006 (PubMed)
    Show all 4 references for 2004946

  8. Human beta-2 Microglobulin Protein expressed in Escherichia coli (E. coli) - ABIN667146 : Huang, Zhau, Chung: Androgen receptor survival signaling is blocked by anti-beta2-microglobulin monoclonal antibody via a MAPK/lipogenic pathway in human prostate cancer cells. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 references for 667146

更多beta-2 Microglobulin互动伙伴

Mouse (Murine) beta-2-Microglobulin (B2M) interaction partners

  1. The results show that, although other factors influence the fibril growth kinetics, a striking difference in the solubility of the proteins is a key determinant of the different amyloidogenicity of human B2M and mouse B2M.

  2. Use of shRNA against beta-2-microglobulin offers a simple and effective approach to minimize immunogenicity of the main cellular components of cardiac tissue constructs in non-syngeneic recipients.

  3. systemic B2M accumulation in aging blood promotes age-related cognitive dysfunction and impairs neurogenesis

  4. Because all forms of H-2K(b) are internalized but little beta2m-receptive heavy chain is present at the cell surface, it is likely that beta2m dissociation and recognition of the heavy chain for lysosomal degradation take place in an endocytic compartment.

  5. We report a novel dichotomous role of beta2m and CD1d, whereby these molecules differently regulate autoimmunity against phospholipid versus non-phospholipid autoantigens.

  6. The goal of the present work was to study peculiarities in functioning of proteasomes and associated signaling pathways along with evaluation of NeuN (显示 RBFOX3 蛋白) and gFAP (显示 GFAP 蛋白) expression in different sections of the brain in mice.

  7. MHC I and b2m genes are both expressed in in human as well as mice during the developmental stages of cerebellar cortex

  8. Knocking out beta 2 microglobulin abolishes NMDAR-dependent LTD in area CA1 of adult mouse hippocampus and is accompanied by memory deficits. MHC class I expression could be an unexpected cause of disrupted synaptic plasticity and cognitive deficits.

  9. This study demonistrated that Deletion of beta-2-microglobulin ameliorates spinal cord lesion load and promotes recovery of brainstem NAA levels in a murine model of multiple sclerosis

  10. Data show that tapasin (显示 TAPBP 蛋白) expression is enhanced by beta 2-microglobulin via both transcriptional and post-transcriptional mechanisms.

Human beta-2-Microglobulin (B2M) interaction partners

  1. Data suggest that T-cell receptor (TCR) alpha-constant domain (C- and F-strands) directly interacts with unbound MHC light chain, beta2-microglobulin (beta2M); these interactions do not appear to be involved in T-cell cytotoxicity, suggesting an alternate role for beta2M binding to TCR; TCR beta-chain does not appear to interact directly with beta2M.

  2. High B2M levels were associated with an increased risk of ischemic stroke in this study of middle-aged women

  3. Letter: serum levels of anti-carbonic anhydrase autoantibodies and beta macroglobulin correlate with ClinESSDAI score in patients with Sjogren's syndrome.

  4. Beta2M mRNA expression in cells of the urinary sediment is higher in T1D patients with diabetic kidney disease and in patients with focal segmental glomerulosclerosis in comparison to healthy subjects, maybe reflecting a tubulointerstitial injury promoted by albumin (显示 ALB 蛋白).

  5. Serum levels of beta trace protein and beta 2 microglobulin can be used to predict residual kidney function in hemodialysis patients.

  6. The chaperone crystallin, which is a mild modulator of the lag (显示 STMN1 蛋白) phase of the variant fibrillogenesis, potently inhibits fibril elongation of the wild-type even once it is absorbed on D76N beta2-microglobulin fibrils.

  7. B2M is a potential tissue biomarker and therapeutic target of borderline and malignant ovarian tumours and the dysregulation of B2M in these tumours may be mediated by the TGF-beta (显示 TGFB1 蛋白) signaling pathway.

  8. BTP and B2M levels are less affected than serum by amputation, and should be considered for future study of GFR (显示 RAPGEF5 蛋白) estimation

  9. Overexpression of B2M are associated with invasion, metastasis of the pancreatic ductal adenocarcinoma.

  10. Serum Beta-2 Microglobulin level is elevated in Chronic Hepatitis C related chronic liver diseases and may be used as a marker for Chronic Hepatitis C disease progression towards cirrhosis and carcinoma.

Pig (Porcine) beta-2-Microglobulin (B2M) interaction partners

  1. B2M contains alpha-helix, beta-sheet, turn, and random coil.

Rhesus Monkey beta-2-Microglobulin (B2M) interaction partners

Zebrafish beta-2-Microglobulin (B2M) interaction partners

蛋白简介beta-2 Microglobulin (B2M)

蛋白简介

This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

Alternative names and synonyms associated with beta-2 Microglobulin (B2M)

  • beta-2-microglobulin (B2M)
  • beta-2 microglobulin (b2m)
  • beta-2 microglobulin (B2m)
  • beta-2-microglobulin (b2m)
  • beta-2-microglobulin (B2m)
  • Beta-2-microglobulin-like (LOC100350679)
  • b2m 蛋白
  • b2m-W01 蛋白
  • b2m-W03 蛋白
  • b2m-Z01 蛋白
  • b2m-Z02 蛋白
  • b2m-Z03 蛋白
  • B2MG 蛋白
  • beta2-m 蛋白
  • beta2m 蛋白
  • bwm 蛋白
  • Ly-m11 蛋白
  • wu:fa94c05 蛋白
  • wu:fb10a09 蛋白

Protein level used designations for beta-2-Microglobulin 蛋白 (B2M)

beta-2-microglobulin , beta-2 microglobulin , Beta-2-microglobulin , beta-2-microglobulin C-terminal fragment (55 AA) , beta2 microglobulin , beta 2-m , beta 2-microglobulin , beta chain of MHC class I molecules , beta-2-microglobin , lactollin , beta 2 microglobulin , beta-2-microglobulin-like protein , beta 2 microglobulin (54 AA)

GENE ID SPECIES
100174579 Pongo abelii
554191 Monodelphis domestica
100136933 Salmo salar
100381194 Papio anubis
100304470 Ictalurus punctatus
24223 Rattus norvegicus
12010 Mus musculus
100379556 Cavia porcellus
100689409 Cricetulus griseus
567 Homo sapiens
397033 Sus scrofa
414830 Gallus gallus
712428 Macaca mulatta
280729 Bos taurus
494145 Felis catus
100034203 Equus caballus
443295 Ovis aries
100855741 Canis lupus familiaris
30400 Danio rerio
101843036 Mesocricetus auratus
100404307 Callithrix jacchus
450170 Pan troglodytes
791104 Ornithorhynchus anatinus
398171 Xenopus laevis
478284 Canis lupus familiaris
100350679 Oryctolagus cuniculus
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