Aurora Kinase B (AURKB) ELISA试剂盒产品概述

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Aurora Kinase B ELISA试剂盒 (AURKB)
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Aik2, AIM-1, Aim1, AIRK2, AL022959, ARK-2, Ark2, Aur B, aurB, aurkb, aurkb-sv1, aurkb-sv2, Aurora-B, aurora B, CG6620, CHUNP6896, DmAIRK2, DmAurB, DmAuroraB, Dmel\\CG6620, fa09g06, Ial, IAL1, IKK2, IPL1, PPP1R48, STK-1, Stk5, Stk12, stka, wu:fa09g06, XAIRK2

Aurora Kinase B (AURKB) ELISA试剂盒 by Reactivity

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适于 Aurora Kinase B 相互作用对的更多 ELISA 试剂盒

Fruit Fly (Drosophila melanogaster) Aurora Kinase B (AURKB) interaction partners

  1. Aurora A (显示 AURKA ELISA试剂盒) and B kinases directly phosphorylate Lgl to promote its mitotic relocalization.

  2. Regulation of Polo (显示 PLK1 ELISA试剂盒) by Aurora B and Map205 is required for cytokinesis.

  3. We propose that mutual inhibitions between Aurora B a (显示 CDK1 ELISA试剂盒)nd Cyclin B regulate the duration of abscission and thereby the number of sister cells in each cyst.

  4. Aurora B kinase activity is not required during contractile ring ingression, providing insight into the mechanism of cytokinesis.

  5. Aurora B interacts with and requires the Cdc37 (显示 CDC37 ELISA试剂盒)/Hsp90 (显示 HSP90 ELISA试剂盒) complex for its stability.

  6. INCENP (显示 INCENP ELISA试剂盒) binds to the cohesion protector protein (显示 PRDX2 ELISA试剂盒) MEI-S332, which is also an excellent in vitro substrate for Aurora B kinase.

Human Aurora Kinase B (AURKB) interaction partners

  1. Aurora B kinase interacts with and phosphorylates Sgo1 (显示 SGOL1 ELISA试剂盒). Aurora B-mediated phosphorylation of Sgo1 (显示 SGOL1 ELISA试剂盒) regulates the distribution of Sgo1 (显示 SGOL1 ELISA试剂盒) between centromeres and chromosome arms.

  2. AURKC (显示 AURKC ELISA试剂盒) rs758099 TT and (CC + CT) genotypes were positively associated with increased intestinal type gastric cancer (GC)risk, but not with an increased diffuse type GC risk. Based on these results, we can conclude that AURKA (显示 AURKA ELISA试剂盒) rs1047972 and AURKC (显示 AURKC ELISA试剂盒) rs758099 polymorphisms could affect the risk of GC development.

  3. Aurora-C (显示 AURKC ELISA试剂盒) interactions with members of the Chromosome Passenger Complex (CPC), Survivin (显示 BIRC5 ELISA试剂盒) and Inner Centromere Protein (INCENP (显示 INCENP ELISA试剂盒)) in reference to known Aurora-B interactions to understand the functional significance of Aurora-C (显示 AURKC ELISA试剂盒) overexpression in human cancer cells, is reported.

  4. Aurora kinase (显示 AURKA ELISA试剂盒) inhibitor danusertib negatively regulated AURKB/p70S6K (显示 RPS6KB1 ELISA试剂盒)/RPL15 (显示 RPL15 ELISA试剂盒) axis with the involvement of PI3K (显示 PIK3CA ELISA试剂盒)/Akt (显示 AKT1 ELISA试剂盒)/mTOR (显示 FRAP1 ELISA试剂盒), AMPK (显示 PRKAA1 ELISA试剂盒), and p38 MAPK (显示 MAPK14 ELISA试剂盒) signaling pathways, leading to the induction of apoptosis and autophagy in human leukemia cells.

  5. The kinase activity of Aurora B on serine 31 of histone H3.3 (显示 H3F3A ELISA试剂盒) was biochemically confirmed with nucleosomal substrates in vitro.

  6. in addition to its role in checkpoint signaling, MAD2 (显示 MAD2L1 ELISA试剂盒) ensures chromosome stability through the regulation of AURORA B.

  7. Ska promotes Aurora B activity to limit its own microtubule and kinetochore association.

  8. partial co-localization of AKT3 (显示 AKT3 ELISA试剂盒) with AURKB was observed during anaphase. Overall, this study suggests that AKT3 (显示 AKT3 ELISA试剂盒) could repress the antiproliferative effects of AURKi, with a novel activity particularly suppressing the aneuploidy induction.

  9. Our study mechanistically explains a p53 (显示 TP53 ELISA试剂盒)-independent mode of action of a chemical Aurora B inhibitor and suggests a potential triggering of antitumoral immune responses, following polyploidization of tumor cells, which might constrain recovery of aneuploid tumor cells.

  10. Our data demonstrate that the cytokinetic proteins epithelial cell transforming 2 and Aurora kinase B (AurkB) are localized to stress granules in human astrocytoma cells

Mouse (Murine) Aurora Kinase B (AURKB) interaction partners

  1. Aurkb phosphorylates Oct4 (显示 POU5F1 ELISA试剂盒)(S229) during G2/M phase, leading to the dissociation of Oct4 (显示 POU5F1 ELISA试剂盒) from chromatin, whereas PP1 (显示 PPP1CC ELISA试剂盒) binds Oct4 (显示 POU5F1 ELISA试剂盒) and dephosphorylates Oct4 (显示 POU5F1 ELISA试剂盒)(S229) during M/G1 transition, which resets Oct4 (显示 POU5F1 ELISA试剂盒)-driven transcription for pluripotency and the cell cycle.

  2. Overexpression of Aurora B (显示 AURKC ELISA试剂盒) also results in a reduced DNA damage response and decreased levels of the p53 (显示 TP53 ELISA试剂盒) target p21(Cip1 (显示 CDKN1A ELISA试剂盒)) in vitro and in vivo.

  3. Chromsome stability is on of the tumor-suppressive functions of ARF as well as regulation of Aurora B (显示 AURKC ELISA试剂盒) expression in tumors.

  4. Using this mutant we show for the first time that AURKC has functions that do not overlap with AURKB. These functions include regulating localized CPC activity and regulating chromosome alignment and K-MT attachments at metaphase of meiosis I (Met I).

  5. reduced accumulation of Aurora B (显示 AURKC ELISA试剂盒) at the inner centromere region in cells lacking Pds5B (显示 PDS5B ELISA试剂盒) impairs its error correction function, promoting chromosome mis (显示 AMH ELISA试剂盒)-segregation and aneuploidy

  6. Aurora B (显示 AURKC ELISA试剂盒) and Ring1B (显示 RNF2 ELISA试剂盒) co-occupy active promoters in resting lymphocytes.

  7. FBXL2 (显示 FBXL2 ELISA试剂盒) mediates Aurora B (显示 AURKC ELISA试剂盒) ubiquitination and degradation within the midbody, which is sufficient to induce mitotic arrest and apoptosis.

  8. Inhibitions of Aurora B (显示 AURKC ELISA试剂盒) and Cyclin-dependent kinase 1 (显示 CDK1 ELISA试剂盒) activity in vertebrate cells also have opposite effects on the timing of abscission.

  9. Aurora B (显示 AURKC ELISA试剂盒) represses p21(Cip1 (显示 CDKN1A ELISA试剂盒)), preventing delayed DNA replication, Cdk (显示 CDK4 ELISA试剂盒) inhibition and premature mitotic exit.

  10. Calmodulin protects Aurora B (显示 AURKC ELISA试剂盒) on the midbody to regulate the fidelity of cytokinesis.

Cow (Bovine) Aurora Kinase B (AURKB) interaction partners

  1. Alterations in PGRMC1 (显示 PGRMC1 ELISA试剂盒) and/or AURKB localization account in part for the increased aneuploidy and low development competence of oocytes from ovaries with reduced antral follicle counts.

  2. AURKB associated with metaphase chromosomes.

Zebrafish Aurora Kinase B (AURKB) interaction partners

  1. Aurora B kinase is essential for furrow induction and maturation in the zebrafish embryo.

Aurora Kinase B (AURKB) 抗原简介

Antigen Summary

This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Aurora Kinase B (AURKB)

  • IplI-aurora-like kinase (ial) Elisa Kit
  • aurora kinase B (aurkb) Elisa Kit
  • aurora kinase B (AURKB) Elisa Kit
  • aurora kinase B (Aurkb) Elisa Kit
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (Ikbkb) Elisa Kit
  • Aik2 Elisa Kit
  • AIM-1 Elisa Kit
  • Aim1 Elisa Kit
  • AIRK2 Elisa Kit
  • AL022959 Elisa Kit
  • ARK-2 Elisa Kit
  • Ark2 Elisa Kit
  • Aur B Elisa Kit
  • aurB Elisa Kit
  • aurkb Elisa Kit
  • aurkb-sv1 Elisa Kit
  • aurkb-sv2 Elisa Kit
  • Aurora-B Elisa Kit
  • aurora B Elisa Kit
  • CG6620 Elisa Kit
  • CHUNP6896 Elisa Kit
  • DmAIRK2 Elisa Kit
  • DmAurB Elisa Kit
  • DmAuroraB Elisa Kit
  • Dmel\\CG6620 Elisa Kit
  • fa09g06 Elisa Kit
  • Ial Elisa Kit
  • IAL1 Elisa Kit
  • IKK2 Elisa Kit
  • IPL1 Elisa Kit
  • PPP1R48 Elisa Kit
  • STK-1 Elisa Kit
  • Stk5 Elisa Kit
  • Stk12 Elisa Kit
  • stka Elisa Kit
  • wu:fa09g06 Elisa Kit
  • XAIRK2 Elisa Kit

Protein level used designations for Aurora Kinase B (AURKB) ELISA试剂盒

AURORA-like , CG6620-PA , DmAuroraB , aurora , aurora B , aurora B kinase , aurora-B , auroraB , dAurora B , ial-PA , aurora/IPL1-related kinase 2 , serine/threonine-protein kinase 12 , serine/threonine-protein kinase aurora-B , xAurora-B , aurora kinase B , serine/threonine-protein kinase 12-like , ARK-2 , STK-1 , aurora 1 , aurora kinase B-Sv1 , aurora kinase B-Sv2 , aurora- and Ipl1-like midbody-associated protein 1 , aurora-1 , aurora-related kinase 2 , protein phosphatase 1, regulatory subunit 48 , serine/threonine kinase 12 , serine/threonine-protein kinase 5 , aurora- and IPL1-like midbody-associated protein 1 , serine/threonine kinase 5 , AIM-1 , Serine/threonine-protein kinase 12 , aurB , cei , cellular island , serine/threonine kinase a , I-kappa-B kinase 2 , I-kappa-B-kinase beta , IKK-B , IKK-beta , NFKBIKB , inhibitor of kappaB kinase beta , inhibitor of nuclear factor kappa B kinase beta subunit , inhibitor of nuclear factor kappa-B kinase subunit beta , nuclear factor NF-kappa-B inhibitor kinase beta

34504 Drosophila melanogaster
549613 Xenopus (Silurana) tropicalis
100301584 Oryzias latipes
100399490 Callithrix jacchus
100448258 Pongo abelii
100528532 Ictalurus punctatus
9212 Homo sapiens
20877 Mus musculus
114592 Rattus norvegicus
479492 Canis lupus familiaris
396955 Sus scrofa
360192 Bos taurus
455095 Pan troglodytes
791894 Danio rerio
84351 Rattus norvegicus
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