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CHRNA7 抗体

(Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from this gene and a novel FAM7A gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
CHRNA7 抗体  (AA 52-259) CHRNA7 抗体  (AA 52-259) CHRNA7 抗体 (AA 52-259) (ABIN5611363)

CHRNA7 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7F10G1 unconjugated

CHRNA7 抗体  (AA 441-502) CHRNA7 抗体  (AA 441-502) CHRNA7 抗体 (AA 441-502) (ABIN736911)

CHRNA7 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

CHRNA7 抗体  (AA 52-259) CHRNA7 抗体  (AA 52-259) CHRNA7 抗体 (AA 52-259) (ABIN5611362)

CHRNA7 适用: 人, 大鼠 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7F10F1 unconjugated

CHRNA7 抗体 by Grade

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CHRNA7 抗体 by 适用

Find CHRNA7 抗体 for a variety of species such as anti-Human CHRNA7, anti-Rat CHRNA7, anti-Mouse CHRNA7. The species listed below are among those available. Click on a link to go to the corresponding products.

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CHRNA7 抗体 by 克隆

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Popular CHRNA7 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (3)
  • (7)
Cat. No. ABIN5611363
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (5)
Cat. No. ABIN736911
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (5)
Cat. No. ABIN5611362
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (3)
Cat. No. ABIN7440818
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7190248
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN6138583
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Application WB
Validations
  • (4)
Cat. No. ABIN2792250
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC, FACS, IF, LCI
Validations
  • (4)
Cat. No. ABIN7043067
Quantity 25 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (2)
Cat. No. ABIN7258754
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN5539917
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (3)
Cat. No. ABIN2774850
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Cow, Guinea Pig, Horse, Human, Monkey, Pig
Application WB
Validations
  • (1)
Cat. No. ABIN202673
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN202671
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application FACS
Validations
  • (2)
Cat. No. ABIN7043069
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN736913
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our CHRNA7 抗体

Bychkov, Kirichenko, Mikhaylova, Paramonov, Kirpichnikov, Shulepko, Lyukmanova: "Extracellular Vesicles Derived from Metastatic Melanoma Cells Transfer α7-nAChR mRNA, Thus Increasing the Surface Expression of the Receptor and Stimulating the Growth of Normal Keratinocytes." in: Acta naturae, Vol. 14, Issue 3, pp. 95-99, (2022) (PubMed).

Bychkov, Shulepko, Shlepova, Kulbatskii, Chulina, Paramonov, Baidakova, Azev, Koshelev, Kirpichnikov, Shenkarev, Lyukmanova: "SLURP-1 Controls Growth and Migration of Lung Adenocarcinoma Cells, Forming a Complex With α7-nAChR and PDGFR/EGFR Heterodimer." in: Frontiers in cell and developmental biology, Vol. 9, pp. 739391, (2021) (PubMed).

Kulbatskii, Shenkarev, Bychkov, Loktyushov, Shulepko, Koshelev, Povarov, Popov, Peigneur, Chugunov, Kozlov, Sharonova, Efremov, Skrebitsky, Tytgat, Kirpichnikov, Lyukmanova: "Human Three-Finger Protein Lypd6 Is a Negative Modulator of the Cholinergic System in the Brain." in: Frontiers in cell and developmental biology, Vol. 9, pp. 662227, (2021) (PubMed).

Garg, Loring: "Evaluating Commercially Available Antibodies for Rat α7 Nicotinic Acetylcholine Receptors." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 65, Issue 9, pp. 499-512, (2017) (PubMed).

Mogoanta, Ciurea, Pirici, Margaritescu, Simionescu, Ion, Pirici: "Different dynamics of aquaporin 4 and glutamate transporter-1 distribution in the perineuronal and perivascular compartments during ischemic stroke." in: Brain pathology (Zurich, Switzerland), Vol. 24, Issue 5, pp. 475-93, (2014) (PubMed).

Severance, Zhang, Cruz, Pakhlevaniants, Hadley, Amin, Wecker, Reed, Cuevas: "The alpha7 nicotinic acetylcholine receptor subunit exists in two isoforms that contribute to functional ligand-gated ion channels." in: Molecular pharmacology, Vol. 66, Issue 3, pp. 420-9, (2004) (PubMed).

Aliases for CHRNA7 抗体

cholinergic receptor nicotinic alpha 7 subunit (CHRNA7) 抗体
neuronal acetylcholine receptor subunit alpha-7 (LOC100374356) 抗体
cholinergic receptor, nicotinic, alpha 7 (neuronal) (chrna7) 抗体
cholinergic receptor, nicotinic, alpha polypeptide 7 (Chrna7) 抗体
cholinergic receptor nicotinic alpha 7 subunit (Chrna7) 抗体
cholinergic receptor, nicotinic, alpha 7 (CHRNA7) 抗体
neuronal acetylcholine receptor subunit alpha-7 (LOC100060521) 抗体
Acra7 抗体
alpha7 抗体
BTX 抗体
CHRNA7 抗体
CHRNA7-2 抗体
dZ70B1.1 抗体
NACHRA7 抗体
nAChRa7 抗体
NARAD 抗体
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