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LIN28A 抗体

(Lin-28 Homolog A (C. Elegans) (LIN28A))
Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting an uridylyltransferase, leading to the terminal uridylation of pre- let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation (By similarity).
LIN28A 抗体  (AA 108-138) LIN28A 抗体  (AA 108-138) LIN28A 抗体 (AA 108-138) (ABIN655156)

LIN28A 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14827 unconjugated

LIN28A 抗体  (N-Term) LIN28A 抗体  (N-Term) LIN28A 抗体 (N-Term) (ABIN6741558)

LIN28A 适用: 人, Cow, 犬, Pig, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

LIN28A 抗体 LIN28A 抗体 LIN28A 抗体 (ABIN7268266)

LIN28A 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

LIN28A 抗体 by 适用

Find LIN28A 抗体 for a variety of species such as anti-Human LIN28A, anti-Mouse LIN28A, anti-Rat LIN28A. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find LIN28A 抗体 validated for a specific application such as WB, ELISA, IF, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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LIN28A 抗体 by 抗原表位

Find LIN28A 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

LIN28A 抗体 by 克隆形成能力

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LIN28A 抗体 by 克隆

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LIN28A 抗体 by 标记

Find LIN28A 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular LIN28A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IF, FACS, IHC (p)
Validations
  • (6)
Cat. No. ABIN655156
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Pig, Sheep
Application WB, IHC, IHC (p)
Validations
  • (4)
Cat. No. ABIN6741558
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN7268266
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, ICC
Validations
  • (2)
  • (3)
Cat. No. ABIN968936
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (3)
Cat. No. ABIN5582592
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, IHC, FACS
Validations
  • (4)
Cat. No. ABIN3031626
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (2)
Cat. No. ABIN7165746
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN6243718
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (2)
Cat. No. ABIN6243717
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN949650
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN529026
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, ICC
Validations
  • (2)
Cat. No. ABIN6972290
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC
Validations
  • (2)
Cat. No. ABIN6143238
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN387790
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, DB
Validations
  • (3)
Cat. No. ABIN3028806
Quantity 0.4 mL
Datasheet Datasheet

Latest Publications for our LIN28A 抗体

Wang, Wan, Xiong, Feng, Wu: "Cancer stem-like cells can be induced through dedifferentiation under hypoxic conditions in glioma, hepatoma and lung cancer." in: Cell death discovery, Vol. 3, pp. 16105, (2017) (PubMed).

Amen, Ruiz-Garzon, Shi, Subramanian, Pham, Meffert: "A Rapid Induction Mechanism for Lin28a in Trophic Responses." in: Molecular cell, Vol. 65, Issue 3, pp. 490-503.e7, (2017) (PubMed).

Boj, Hwang, Baker, Chio, Engle, Corbo, Jager, Ponz-Sarvise, Tiriac, Spector, Gracanin, Oni, Yu, van Boxtel, Huch, Rivera, Wilson, Feigin, Öhlund, Handly-Santana, Ardito-Abraham, Ludwig, Elyada et al.: "Organoid models of human and mouse ductal pancreatic cancer. ..." in: Cell, Vol. 160, Issue 1-2, pp. 324-38, (2015) (PubMed).

Gerecht-Nir, Dazard, Golan-Mashiach, Osenberg, Botvinnik, Amariglio, Domany, Rechavi, Givol, Itskovitz-Eldor: "Vascular gene expression and phenotypic correlation during differentiation of human embryonic stem cells." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 232, Issue 2, pp. 487-97, (2005) (PubMed).

Wu, Belasco: "Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells." in: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9198-208, (2005) (PubMed).

Aliases for LIN28A 抗体

lin-28 homolog A (LIN28A) 抗体
lin-28 homolog A (C. elegans) (Lin28a) 抗体
lin-28 homolog A S homeolog (lin28a.S) 抗体
lin-28 homolog A (C. elegans) (lin28a) 抗体
lin-28 homolog A (Lin28a) 抗体
lin-28 homolog A (lin28a) 抗体
AL024421 抗体
CSDD1 抗体
csdd1 抗体
ENSMUSG00000070700 抗体
Gm10299 抗体
LIN-28 抗体
Lin-28 抗体
lin-28 抗体
lin-28A 抗体
LIN28 抗体
Lin28 抗体
lin28 抗体
RGD1566408 抗体
sb:cb650 抗体
Tex17 抗体
ZCCHC1 抗体
zcchc1 抗体
zgc:55584 抗体
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