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抗Human NRP2 抗体:
抗Mouse (Murine) NRP2 抗体:
抗Rat (Rattus) NRP2 抗体:
Rat (Rattus) Monoclonal NRP2 Primary Antibody for IF, WB - ABIN968443
Chen, Chédotal, He, Goodman, Tessier-Lavigne: Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III. in Neuron 1997
Show all 4 Pubmed References
Human Polyclonal NRP2 Primary Antibody for WB - ABIN442214
Roth, Agemy, Kotamraju, Braun, Teesalu, Sugahara, Hamzah, Ruoslahti: Transtumoral targeting enabled by a novel neuropilin-binding peptide. in Oncogene 2012
Cow (Bovine) Polyclonal NRP2 Primary Antibody for IHC, ELISA - ABIN1582215
Hey-Cunningham, Markham, Fraser, Berbic: Dysregulation of vascular endothelial growth factors and their neuropilin receptors in the eutopic endometrium of women with endometriosis. in Reproductive sciences (Thousand Oaks, Calif.) 2013
Human Monoclonal NRP2 Primary Antibody for CyTOF, FACS - ABIN4899777
Jaalouk, Ozawa, Sun, Lahdenranta, Schlingemann, Pasqualini, Arap: The original Pathologische Anatomie Leiden-Endothelium monoclonal antibody recognizes a vascular endothelial growth factor binding site within neuropilin-1. in Cancer research 2007
Human Polyclonal NRP2 Primary Antibody for WB - ABIN655525
Davare, Lal, Peckham, Prajapati, Gultekin, Rubin, Keller: Secreted meningeal chemokines, but not VEGFA, modulate the migratory properties of medulloblastoma cells. in Biochemical and biophysical research communications 2014
Human Polyclonal NRP2 Primary Antibody for IHC, IHC (p) - ABIN4338865
Fonseca, Bingle, Santos-Silva, Lopes, de Almeida, de Andrade, Mariano, Kowalski, Rangel, Martins, Meurer, Speight, Vargas: Semaphorins and neuropilins expression in salivary gland tumors. in Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2016
Neuropilin 2 isoform NRP2b contributed to the oncogenic response to transforming growth factor-beta (TGFbeta (显示 TGFB1 抗体)) and correlated with tumor progression in non-small cell lung cancer (NSCLC) patients.
Sema3a (显示 SEMA3A 抗体)-Nrp2 (显示 NELL2 抗体) signaling along an unrecognized pancreatic developmental axis constitutes a chemoattractant system essential for generating the hallmark morphogenetic properties of pancreatic islets.
NRP2 (显示 NELL2 抗体) promotes tumourigenesis and metastasis in Oesophageal squamous cell carcinoma (ESCC) through deregulation of ERK-MAPK (显示 MAPK1 抗体)-ETV4 (显示 ETV4 抗体)-MMP-E-cadherin (显示 CDH1 抗体) signalling.
The summarizes the structure and function features of pathway-related molecules of VEGFC (显示 VEGFC 抗体)/D-VEGFR3 (显示 FLT4 抗体)/NRP2 (显示 NELL2 抗体) axis, stages of various tumors and their molecular mechanisms and significances in tuthe expression changes of these molecules in different anatomic organs or histopathologic types or development lymphatic metastasis.
NRP2 (显示 NELL2 抗体) inhibits WDFY1 (显示 WDFY1 抗体) transcription by preventing the nuclear localization of a transcription factor, Fetal ALZ50-reactive clone 1 (FAC1 (显示 BPTF 抗体)).
Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV (显示 ST8SIA4 抗体) and Polysialylation of Its O-Glycans.
the concurrent high expression of VEGF-C (显示 VEGFC 抗体) and NRP2 (显示 NELL2 抗体) is predictive of the unfavorable prognosis in glioblastoma.
SEMA3F (显示 SEMA3F 抗体)-NRP2 (显示 NELL2 抗体) interactions inhibit intracellular PI-3K activity, mTORC2 (显示 CRTC2 抗体)-dependent signaling, RhoA (显示 RHOA 抗体) activity and cytoskeletal stress fiber formation.
NRP2 (显示 NELL2 抗体)/WDFY1 (显示 WDFY1 抗体) axis is required for maintaining endocytic activity in cancer cells, which supports their oncogenic activities and confers drug resistance.
Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels.
Sema3G (显示 SEMA3G 抗体) induces cell collapse in an Nrp2/PlexinD1-dependent manner.
Sema3a (显示 SEMA3A 抗体)-Nrp2 signaling along an unrecognized pancreatic developmental axis constitutes a chemoattractant system essential for generating the hallmark morphogenetic properties of pancreatic islets.
Nrp2 deficiency increased blood vessel permeability and decreased lymphatic vessel drainage during inflammation, highlighting the importance of the NRP2/SEMA3F (显示 SEMA3F 抗体) pathway in the modulation of tissue swelling and resolution of postinflammatory edema.
These results point to a new role for NRP2 in the positioning of neurons during adult hippocampal neurogenesis, acting via the GSK3beta (显示 GSK3b 抗体) signaling pathway.
The authors demonstrate that expression of Semaphorin-3F (显示 SEMA3F 抗体) in the outer hair cell region inhibits type I spiral ganglion neuron process extension by activating Neuropilin-2 receptors expressed on spiral ganglion neurons.
neuropilin-2 is developmentally regulated.
Data show that Chicken ovalbumin upstream promoter transcription factor (显示 NR2F1 抗体) II (COUP-TFII (显示 NR2F2 抗体))-induced expression of Neuropilin-2 (Nrp2) and its down-regulation control the destination of preoptic area (POa)-derived GABAergic neurons.
Study demonstrates that polysialic acid-SynCAM 1 (显示 CADM1 抗体) defines a subpopulation of NG2 (显示 Vcan 抗体) cells and identifies the presence of polysialic acid-NRP2 in microglia
This study suggested that neuropilins play an essential role in coordinating NCC (显示 SLC12A3 抗体) migration with fate specification.
High NRP2 expression is associated with medulloblastoma.
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C and SEMA3F protein sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
, receptor for VEGF165 and semaphorins class3
, vascular endothelial cell growth factor 165 receptor 2