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Data indicate that miR (显示 MLXIP ELISA试剂盒)-206's effect on Myc (显示 MYC ELISA试剂盒) was mediated through MAP3K13.
LZK cooperates with DLK (显示 DAPK3 ELISA试剂盒) to promote retinal ganglion cell death in response to axon injury.
Chromosomal localization studies involving FISH mapping demonstrated that the human LZK gene is located at 3q27.
Scaffold protein (显示 HOMER1 ELISA试剂盒) POSH (显示 SH3RF1 ELISA试剂盒), in association with Shroom3 (显示 SHROOM3 ELISA试剂盒) and mixed lineage kinase LZK, relays axon outgrowth inhibition downstream of NogoA (显示 RTN4 ELISA试剂盒) and PirB (显示 LILRB3 ELISA试剂盒) proteins.
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway.
leucine zipper-bearing kinase
, mitogen-activated protein kinase kinase kinase 13
, mitogen activated protein kinase kinase kinase 13 type A
, mitogen-activated protein kinase kinase kinase 13-A
, mixed lineage kinase
, mitogen activated protein kinase kinase kinase 13