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抗Mouse (Murine) 抗体:
Human Monoclonal MAP3K13 Primary Antibody for WB - ABIN1882198
Ikeda, Hasegawa, Masaki, Moriguchi, Nishida, Kozutsumi, Oka, Kawasaki: Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway. in Journal of biochemistry 2001
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Data indicate that miR (显示 MLXIP 抗体)-206's effect on Myc (显示 MYC 抗体) was mediated through MAP3K13.
LZK cooperates with DLK (显示 DAPK3 抗体) to promote retinal ganglion cell death in response to axon injury.
Chromosomal localization studies involving FISH mapping demonstrated that the human LZK gene is located at 3q27.
Scaffold protein (显示 HOMER1 抗体) POSH (显示 SH3RF1 抗体), in association with Shroom3 (显示 SHROOM3 抗体) and mixed lineage kinase LZK, relays axon outgrowth inhibition downstream of NogoA (显示 RTN4 抗体) and PirB (显示 LILRB3 抗体) proteins.
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway.
leucine zipper-bearing kinase
, mitogen-activated protein kinase kinase kinase 13
, mitogen activated protein kinase kinase kinase 13 type A
, mitogen-activated protein kinase kinase kinase 13-A
, mixed lineage kinase
, mitogen activated protein kinase kinase kinase 13