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COL4a3 ELISA试剂盒

(Collagen, Type IV, alpha 3 (COL4A3))

Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In the Goodpasture syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein. A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis. This gene is also linked to an autosomal recessive form of Alport syndrome. The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jun 2010].

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COL4a3 ELISA 试剂盒 (ABIN6954946)

COL4A3 适用: 人 Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate

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Find COL4a3 ELISA试剂盒 for a variety of species such as anti-Human COL4a3. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular COL4a3 ELISA试剂盒

Product

Reactivity

Analytical Method

Validations

Cat. No.

Quantity

Datasheet

COL4a3 ELISA 试剂盒

Reactivity Human

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6954946

Quantity 96 tests

Datasheet Datasheet

Latest Publications for our COL4a3 ELISA试剂盒

Tan, ONeill, Naciri, Dowling, Al-Rubeai: "Cellular and transcriptomic analysis of human mesenchymal stem cell response to plasma-activated hydroxyapatite coating." in: Acta biomaterialia, Vol. 8, Issue 4, pp. 1627-38, (2012) (PubMed).

Aliases for COL4a3 ELISA试剂盒

collagen type IV alpha 3 chain (COL4A3) ELISA试剂盒
collagen, type IV, alpha 3 (col4a3) ELISA试剂盒
collagen, type IV, alpha 3 (Col4a3) ELISA试剂盒
collagen type IV alpha 3 chain (Col4a3) ELISA试剂盒
alpha3(IV) ELISA试剂盒
zTumstatin ELISA试剂盒
[a]3(IV) ELISA试剂盒

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