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anti-VEGF (VEGFA) 抗体产品概述

Full name:
anti-Vascular Endothelial Growth Factor A 抗体 (VEGFA)
在www.antibodies-online.cn可供359 Vascular Endothelial Growth Factor A (VEGFA) 抗体的33不同的供货商。 再加上,我们可以发VEGF 蛋白 (130)VEGF 试剂盒 (111)和数多这个蛋白质的别的产品。 总共617 VEGF产品已列进来了。
别名:
eVEGF120, eVEGF164, MVCD1, vefg, Vegf, VEGF-A, Vegf120, VEGF164, Vegf188, vegfa, Vpf, wu:fj82c06

所有可销售的anti-VEGF 抗体

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引用最多的anti-VEGF 抗体

  1. Human Polyclonal VEGF Primary Antibody for EIA, WB - ABIN955508 : Shrivastava-Ranjan, Rollin, Spiropoulou: Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin. in Journal of virology 2010 (PubMed)
    Show all 5 references for ABIN955508

  2. Guinea Pig Polyclonal VEGF Primary Antibody for IF (p), IHC (p) - ABIN707186 : Wang, Liao, Wang, Deng, Yu: Transplantation of bone marrow stromal cells overexpressing human vascular endothelial growth factor 165 enhances tissue repair in a rat model of radiation-induced injury. in Chinese medical journal 2014 (PubMed)
    Show all 3 references for ABIN707186

  3. Human Polyclonal VEGF Primary Antibody for EIA, IHC (p) - ABIN155190 : Breier, Albrecht, Sterrer, Risau: Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. in Development (Cambridge, England) 1992 (PubMed)
    Show all 3 references for ABIN155190

  4. Human Monoclonal VEGF Primary Antibody for EIA, Func - ABIN155173 : Kim, Li, Houck, Winer, Ferrara: The vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies. in Growth factors (Chur, Switzerland) 1992 (PubMed)
    Show all 2 references for ABIN155173

  5. Human Monoclonal VEGF Primary Antibody for Func - ABIN180646 : Brown, Berse, Jackman, Tognazzi, Guidi, Dvorak, Senger, Connolly, Schnitt: Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. in Human pathology 1995 (PubMed)

  6. Human Polyclonal VEGF Primary Antibody for IF (p), IHC (p) - ABIN675893 : Ryzhov, Goldstein, Novitskiy, Blackburn, Biaggioni, Feoktistov: Role of A2B adenosine receptors in regulation of paracrine functions of stem cell antigen 1-positive cardiac stromal cells. in The Journal of pharmacology and experimental therapeutics 2012 (PubMed)

  7. Human Monoclonal VEGF Primary Antibody for FACS - ABIN4898939 : Lee, Myers, Kim: Vascular endothelial growth factor drives autocrine epithelial cell proliferation and survival in chronic rhinosinusitis with nasal polyposis. in American journal of respiratory and critical care medicine 2009 (PubMed)

  8. Human Monoclonal VEGF Primary Antibody for IHC (p) - ABIN114925 : Turley, Scott, Watts, Bicknell, Harris, Gatter: Expression of VEGF in routinely fixed material using a new monoclonal antibody VG1. in The Journal of pathology 1999 (PubMed)

更多抗VEGF的相互作用对抗体

Zebrafish Vascular Endothelial Growth Factor A (VEGFA) interaction partners

  1. altering the amount of VEGF signaling in endothelial cells by stimulating them with different VEGF concentrations triggered distinct and mutually exclusive dynamic Ca(2 (显示 CA2 抗体)+) signaling responses that correlated with different cellular behaviors.

  2. Bis(2,3-dibromo-4,5-dihydroxybenzyl) ether downregulate the expression of VEGF and VEGFR, and simultaneously regulates VEGF signaling pathway to prevent angiogenesis.

  3. noncanonical function of tars (显示 TARS 抗体) regulates vascular development presumably by modulating the expression of vegfa

  4. Methylglyoxal acts on smaller blood vessels in zebrafish via the VEGF receptor (显示 FLT1 抗体) signaling cascade, thereby describing a new mechanism that can explain vascular complications under hyperglycemia and elevated MG concentrations.

  5. The translation initiation factor eIF3i (显示 EIF3I 抗体) up-regulates VEGF-A, accelerates cell proliferation, and promotes angiogenesis in embryonic development.

  6. lack of SULF1 (显示 SULF1 抗体) expression downregulates VEGFA-mediated arterial marker expression, confirming that Sulf1 (显示 SULF1 抗体) mediates arterial specification by regulating VegfA165 activity.

  7. yolk-derived 17beta-estradiol sets the ventral boundary of hemogenic vascular niche specification by antagonizing the dorsal-ventral regulatory limits of VEGF.

  8. Vegfaa has a crucial role in angiogenesis and vegfaa expression was upregulated in embryos lacking functional Pten (显示 PTEN 抗体).

  9. Over expression of zebrafish vegf-a rescues Methyl tert (显示 TERT 抗体)-butyl ether induced vascular lesions.

  10. Elevated Notch (显示 NOTCH1 抗体) signaling downstream of perturbed VEGF signaling contributes to aberrant flt-1 (显示 FLT1 抗体)(-/-) blood vessel formation.

Xenopus laevis Vascular Endothelial Growth Factor A (VEGFA) interaction partners

  1. VEGFA produced in the somites is required to initiate adult haemangioblast programming in the adjacent dorsal lateral plate mesoderm.

  2. sequential, isoform-specific VEGFA signaling successively induces the endothelial, arterial, and hematopoietic stem cell programs in the dorsal aorta.

  3. VEGF induces stromal cell migration or recruitment that are required for blood vessel formation.

  4. increased VEGF(170) levels disturb Hand-1 (显示 HAND1 抗体) expression in the region required for normal heart morphogenesis

Cow (Bovine) Vascular Endothelial Growth Factor A (VEGFA) interaction partners

  1. data for the first time demonstrate a calpain/PTP1B/VEGFR2 negative feedback loop in the regulation of VEGF-induced angiogenesis. Modulation of local PTP1B and/or calpain activities may prove beneficial in the treatment of impaired wound healing in diabetes.

  2. Studied the effect of cyclic uniaxial stretch (20%, 1 Hz), with and without the stimulation of vascular endothelial growth factor (VEGF), on sprouting angiogenesis by employing a stretchable three-dimensional cell culture model.

  3. Study shows that VEGFA mRNA in mammalian endothelial cells undergoes programmed translational readthrough (PTR) generating VEGF-Ax, an isoform containing a unique 22-amino-acid C terminus extension.

  4. Data indicate that superoxide dismutase (SOD) inhibited high glucose (HG)-induced expression of uPAR and VEGF in bovine retinal microvascular endothelial cell (REC).

  5. Exposure of endothelial cells to VEGF, high glucose, or hydrogen peroxide up-regulated the XBP1 (显示 XBP1 抗体)/IRE1 alpha (显示 ERN1 抗体) and ATF6 (显示 ATF6 抗体) arms of the unfolded protein response compared with untreated cells.

  6. Microvascular endothelial cells are more susceptible than aortic cells to advanced glycation end products-enhanced permeability and that AGE-enhanced permeability is dependent on VEGF expression induced by reactive oxygen species.

  7. VEGF supports germ cell survival and sperm production in bulls.

  8. analysis of polymorphisms of bovine VEGF gene and their associations with growth traits in Chinese cattle

  9. VEGF mRNA expression at estrus was higher than at the early I, early II and late luteal stages (P<0.05), whereas VEGF protein content was greatest at the early I luteal stage and decreased thereafter

  10. Alterations in the expression of VEGF-A and bFGF (显示 FGF2 抗体) systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.

Human Vascular Endothelial Growth Factor A (VEGFA) interaction partners

  1. Varying degrees of immunoreactivity to Cyclin D1 (显示 CCND1 抗体), VEGF, and EZH2 (显示 EZH2 抗体) were noted in the majority of the AT/RTs (显示 RECQL4 抗体), and detection of these markers may be of value in the development of novel therapeutic agents and in determining which patients can benefit from them

  2. VEGF-A165a mRNA expression and VEGF-A protein production were significantly increased after incubation with glyoxal in ARPE-19 cells

  3. VEGF-A driven Mdm2 (显示 MDM2 抗体) phosphorylation on Ser166 is dependent on the ERK1/2 (显示 MAPK1/3 抗体)/p90RSK (显示 RPS6KA1 抗体) signaling pathway in primary human endothelial cells.

  4. data for the first time demonstrate a calpain/PTP1B/VEGFR2 negative feedback loop in the regulation of VEGF-induced angiogenesis. Modulation of local PTP1B and/or calpain activities may prove beneficial in the treatment of impaired wound healing in diabetes.

  5. miR (显示 MLXIP 抗体)-361-5p is down-regulated in 135 patients with HCV-related hepatocellular carcinoma (HCC (显示 FAM126A 抗体)). Moreover, the expressions of miR (显示 MLXIP 抗体)-361-5p were highly correlated with VEGFA in these HCC (显示 FAM126A 抗体) patients.

  6. These findings suggest that VEGF blockade is a robust strategy to enhance cartilage repair by endogenous or grafted mesenchymal progenitors.

  7. Angiogenesis in Infantile haemangioma (IH) appears to be controlled by DLL4 (显示 DLL4 抗体) within the endothelium in a VEGF-A isoform-dependent manner, and in perivascular cells in a VEGF-independent manner. The contribution of VEGF-A isoforms to disease progression also indicates that IH may be associated with altered splicing.

  8. The encouraging overall survival and favorable safety profile observed with sonepcizumab should prompt further investigation of the agent in combination with VEGF-directed agents or checkpoint inhibitors.

  9. The CRISPR-Cas9 endonuclease system may reduce VEGF-A secretion from human RPE (显示 RPE 抗体) cells and suppress angiogenesis, supporting the possibility of employing gene editing for antiangiogenesis therapy in ocular diseases.

  10. Using a combination of cytokine expression profiling and miRNAs algorithms, we identified VEGFA/CCL2 (显示 CCL2 抗体) and FOXO3a (显示 FOXO3 抗体) as direct targets of miR-1 (显示 FSD1 抗体), miR (显示 MLXIP 抗体)-206 and miR (显示 MLXIP 抗体)-31, respectively. Importantly, systemic delivery of anti-VEGFA/CCL2 (显示 CCL2 抗体) or pre-miR-1 (显示 FSD1 抗体), pre-miR (显示 MLXIP 抗体)-206 and anti-miR (显示 MLXIP 抗体)-31 significantly inhibited tumor angiogenesis, TAMs accumulation, tumor growth and lung metastasis.

Mouse (Murine) Vascular Endothelial Growth Factor A (VEGFA) interaction partners

  1. First-in-class selective PET tracers for imaging VEGFR-1 (显示 FLT1 抗体) and VEGFR-2 (显示 KDR 抗体) were constructed and successfully validated in an orthotopic murine tumor model.

  2. data for the first time demonstrate a calpain/PTP1B/VEGFR2 negative feedback loop in the regulation of VEGF-induced angiogenesis. Modulation of local PTP1B and/or calpain activities may prove beneficial in the treatment of impaired wound healing in diabetes.

  3. The results demonstrate that the Vegf-Dll4 (显示 DLL4 抗体)/Notch (显示 NOTCH1 抗体) feedback system normally operates to generate heterogeneity between endothelial cells driving blood vessel branching, whilst synchronization drives vessel expansion.

  4. Ginkgo biloba exocarp extract inhibits tumor angiogenesis, which may be closely relevant to its effect in blockage of Wnt /beta-catenin-VEGF signaling pathway in Lewis lung carcinoma.

  5. D2R agonist treatment blocks tumor growth, induces regression of the aberrant blood supply and normalizes blood vessels. An anti-Vegf therapy is also effective to restrain tumor growth and improves vascular remodeling. Importantly, only the combination treatment suppresses intratumoral hemorrhage and restores blood vessel perfusion, suggesting that it might represent an attractive therapy targeting tumor vasculature

  6. VEGF-A mRNA and protein expression were upregulated in choroidal neovascularization; these changes were ameliorated by restoration of miR (显示 MLXIP 抗体)-93 by means of transfection.

  7. These results indicate that tensile force induces in vivo gene expression associated with vascularization early in tensile-force-induced sutural bone formation. Moreover, the early induction of Vegf gene expression is regulated by CTGF (显示 CTGF 抗体) and ROCK2 (显示 ROCK2 抗体).

  8. Combining VEGF165 obviously enhanced the inducing effects of BMP2 (显示 BMP2 抗体) on osteogenic differentiation capacity of C3H10T1/2 cells.

  9. our results clearly indicate that the two major VEGF isoforms are not redundant in inducing and regulating tumor angiogenesis, as they can exert even opposite effects on the growth and invasion of cancer cells in vivo.

  10. Endothelial cell-specific endoglin expression in islets of Langerhans is sensitive to VEGF and plays partial roles in driving islet vascular development, however such regulation appears to be distinct to mechanisms required to modulate islet viability and size.

Pig (Porcine) Vascular Endothelial Growth Factor A (VEGFA) interaction partners

  1. Here we demonstrate that VEGF-165 mediates MSC (显示 MSC 抗体) differentiation into ECs via VEGFR-2 (显示 KDR 抗体)-dependent induction of Sox18 (显示 SOX18 抗体), which ultimately coordinates the transcriptional upregulation of specific markers of the EC phenotype.

  2. VEGF was significantly downregulated 7 days after cryotherapy of the sclera and stayed at that level until day 14. It returned to baseline by day 21.

  3. VEGF production, blood vessel network and follicle remodeling are impaired by the antiprogesterone RU486.

  4. findings suggest that the augmented neovascular response seen with VEGF administration was through the VEGF-induced upregulation of Notch (显示 NOTCH1 抗体) signaling.

  5. interleukin-1beta-induced vascular endothelial growth factor in airway smooth muscle cells

  6. Upregulation of VEGF during hypoxia in chondrocyte is mediated partially through HIF-1alpha (显示 HIF1A 抗体).

  7. data shows that members of the VEGF-VEGFR (显示 KDR 抗体) system are temporally and spatially well localized for playing key roles during umbilical cord formation and its intensive growth observed after day 75 of pregnancy

  8. cardiac-specific and hypoxia-induced coexpression of VEGF and Ang1 (显示 ANGPT1 抗体) improves the perfusion and function of porcine MI heart through the induction of angiogenesis and cardiomyocyte proliferation

  9. The mRNA for VEGFA was expressed in early developing and in maturing glomeruli.

  10. Data show that subventricular zone neural stem cells express VEGF and all VEGF splice variants, VEGFR1 (显示 FLT1 抗体), VEGFR2 (显示 KDR 抗体) and Neuropilin-1 (显示 NRP1 抗体) and -2 mRNAs.

Horse (Equine) Vascular Endothelial Growth Factor A (VEGFA) interaction partners

  1. Peripheral Blood-Derived Mesenchymal Stromal Cells Promote Angiogenesis via Paracrine Stimulation of Vascular Endothelial Growth Factor Secretion

  2. TNF (显示 TNF 抗体) may up-regulate VEGF and stimulate angiogenesis in the mare (显示 C16orf35 抗体) early corpus luteum.

Guinea Pig Vascular Endothelial Growth Factor A (VEGFA) interaction partners

  1. After acoustic trauma, vascular endothelial growth factor was up-regulated both in the cochlea and vestibule. Expression in both structures suggests a reparative role with potentially therapeutic implications.

  2. Studied the role of T help 17 cells (Th17) and STAT3-VEGF pathway in pathogenesis of psoriasis.

Rabbit Vascular Endothelial Growth Factor A (VEGFA) interaction partners

  1. VEGF mRNA abundance was present at low levels at 16 h post-ovulation and remained low at 72 h, but the level increased at 144 h in uterus.

  2. correlation was observed between CT perfusion parameters (BF, BV, PS, and MAV (显示 KLHL2 抗体)) and expression of VEGF and MVD (显示 MVD 抗体) in tumor tissue

  3. Physiologic ischemic training stimulates VEGF-mediated mobilization of endothelial progenitor cells as well as angiogenesis.

  4. Suggest supplemental oxygen inhibits HIF-1alpha/VEGF signaling to reduce smooth muscle proliferation in rabbit arteriovenous fistula model.

  5. Therefore, it was reasonable to speculate that the increased expression of VEGF and MMP-9 (显示 MMP9 抗体) in residual hepatic tumor cells and tumor angiogenesis post-embolization would be responsible for the increased metastatic potentiality and invasiveness.

  6. VEGF expression peaked at 8 weeks after meniscus transplantation

  7. Studied the biocompatibility and neovascularization of the PLGA nanospheres wrapped with vascular endothelial growth factor (VEGF).

  8. VEGF induces TGF-beta1 (显示 TGFB1 抗体) expression and myofibroblast transformation after glaucoma surgery.

  9. The results of this study are promising concerning the role of VEGF as a diagnostic marker in moderate osteoarthritis

  10. The overexpression of VEGF increased tumor growth and vascularization, favored cyst formation, and reduced tumor necrosis.

Rhesus Monkey Vascular Endothelial Growth Factor A (VEGFA) interaction partners

  1. VEGF plays an important role in choroid-retinal endothelial cell proliferation and tube formation.

  2. These findings suggest that FBLN5 (显示 FBLN5 抗体) may interfere with choroidal neovascularization by downregulating VEGF, CXCR4 (显示 CXCR4 抗体), and TGFB1 (显示 TGFB1 抗体) expression and inhibiting choroidl endothelial cell proliferation.

  3. Apelin may play a role in the development of central retinal vein occlusion (CRVO). Apelin has a unique upstream signaling pathway, independent of the VEGF pathway.

  4. Dll4 play an important role in choroidal neovascularization (CNV) angiogenesis, which appears to be regulated by HIF-1alpha and VEGF during the progression of CNV under hypoxic conditions.

  5. A functional network involving VEGF, IGF2, and MMP9 (显示 MMP9 抗体) in early placental trophoblast cells and maternal endometrium appears to be important for normal placentation.

VEGF (VEGFA) 抗原简介

Antigen Summary

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.

Alternative names and synonyms associated with VEGF (VEGFA)

  • vascular endothelial growth factor Aa (vegfaa) 抗体
  • vascular endothelial growth factor A (vegfa-a) 抗体
  • vascular endothelial growth factor A (VEGFA) 抗体
  • vascular endothelial growth factor A (vegfa) 抗体
  • vascular endothelial growth factor A (Vegfa) 抗体
  • eVEGF120 抗体
  • eVEGF164 抗体
  • MVCD1 抗体
  • vefg 抗体
  • Vegf 抗体
  • VEGF-A 抗体
  • Vegf120 抗体
  • VEGF164 抗体
  • Vegf188 抗体
  • vegfa 抗体
  • Vpf 抗体
  • wu:fj82c06 抗体

Protein level used designations for VEGFA

VEGF-A-A , etID309976.16 , vascular endothelial growth factor A , vascular endothelial growth factor A-A , vegf-a , vascular endothelial growth factor A-a , vascular endothelial growth factor 164 , vascular permeability factor , VEGF-A , VPF , vascular endothelial growth factor 188 , angiogenic factor , Vascular permeability factor , endothelial growth factor-164 , vascular endothelial growth factor VEGF

GENE ID SPECIES
30682 Danio rerio
373589 Xenopus laevis
493845 Felis catus
100038089 Xenopus (Silurana) tropicalis
281572 Bos taurus
7422 Homo sapiens
22339 Mus musculus
83785 Rattus norvegicus
397157 Sus scrofa
403802 Canis lupus familiaris
395909 Gallus gallus
100033839 Equus caballus
443103 Ovis aries
100713483 Cavia porcellus
100860957 Capra hircus
100008899 Oryctolagus cuniculus
101839822 Mesocricetus auratus
574209 Macaca mulatta
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