anti-TRKA (NTRK1) 抗体产品概述

Full name:
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 抗体 (NTRK1)
在www.antibodies-online.cn可供443 Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) 抗体的30不同的供货商。 再加上,我们可以发TRKA 试剂盒 (36)TRKA 蛋白 (27)和数多这个蛋白质的别的产品。 总共530 TRKA产品已列进来了。
别名:
C80751, CAPM1, CFTD, CTRKA, hscp30, MTC, NEM1, OK/SW-cl.5, p140-TrkA, Tkr, TM-5, TM3, TM5, TM30, TM30nm, TPMsk3, Trk, Trk-A, TRK1, trkA

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引用最多的anti-TRKA 抗体

  1. Human Polyclonal TRKA Primary Antibody for EIA, WB - ABIN358249 : Tacconelli, Farina, Cappabianca, Desantis, Tessitore, Vetuschi, Sferra, Rucci, Argenti, Screpanti, Gulino, Mackay: TrkA alternative splicing: a regulated tumor-promoting switch in human neuroblastoma. in Cancer cell 2004 (PubMed)
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  2. Human Polyclonal TRKA Primary Antibody for EIA, WB - ABIN453859 : Tokusashi, Asai, Tamakawa, Yamamoto, Yoshie, Yaginuma, Miyokawa, Aoki, Kino, Kasai, Ogawa: Expression of NGF in hepatocellular carcinoma cells with its receptors in non-tumor cell components. in International journal of cancer. Journal international du cancer 2005 (PubMed)
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  3. Human Polyclonal TRKA Primary Antibody for EIA, WB - ABIN359950 : Schulte, Schramm, Klein-Hitpass, Klenk, Wessels, Hauffa, Eils, Eils, Brodeur, Schweigerer, Havers, Eggert: Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas. in Oncogene 2005 (PubMed)
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  4. Human Polyclonal TRKA Primary Antibody for IF - ABIN401580 : Wiese, Jablonka, Holtmann, Orel, Rajagopal, Chao, Sendtner: Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 3 references for 401580

  5. Human Polyclonal TRKA Primary Antibody for IHC (p), IP - ABIN127050 : Segal, Greenberg: Intracellular signaling pathways activated by neurotrophic factors. in Annual review of neuroscience 1997 (PubMed)
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  6. Human Monoclonal TRKA Primary Antibody for ICC, ELISA - ABIN969444 : Geetha, Wooten: TrkA receptor endolysosomal degradation is both ubiquitin and proteasome dependent. in Traffic (Copenhagen, Denmark) 2008 (PubMed)
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  7. Human Polyclonal TRKA Primary Antibody for IF (p), IHC (p) - ABIN726110 : Li, Shen, Di, Li, Geng, Lu, He: Biological and clinical significance of p75NTR expression in laryngeal squamous epithelia and laryngocarcinoma. in Acta oto-laryngologica 2012 (PubMed)

  8. Human Monoclonal TRKA Primary Antibody for FACS - ABIN4897419 : Foveau, Ancot, Leroy, Petrelli, Reiss, Vingtdeux, Giordano, Fafeur, Tulasne: Down-regulation of the met receptor tyrosine kinase by presenilin-dependent regulated intramembrane proteolysis. in Molecular biology of the cell 2009 (PubMed)

  9. Human Monoclonal TRKA Primary Antibody for FACS - ABIN4897415 : Paczkowska, Kaczy?ska, Pius-Sadowska, Rogi?ska, Kawa, Ustianowski, Safranow, Celewicz, Machali?ski: Humoral activity of cord blood-derived stem/progenitor cells: implications for stem cell-based adjuvant therapy of neurodegenerative disorders. in PLoS ONE 2014 (PubMed)

更多抗TRKA的相互作用对抗体

Zebrafish Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) interaction partners

  1. TrkA-like immunoreactivity was the only Trk detected, and it was restricted to the somata of crypt sensory neurons, their central processes being apparently unreactive.

Rabbit Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) interaction partners

  1. report describing differential expression of proteins and mRNA for NGF (显示 NGFB 抗体) and its cognate receptors, NTRK1 and NGFR (显示 NGFR 抗体), in the male sex organs of rabbits

Human Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) interaction partners

  1. A novel nonsense mutation and a known splice-site mutation were detected in NTRK1 in two siblings and were shown to be associated with congenital insensitivity to pain with anhidrosis.

  2. NT3 (显示 NTF3 抗体) upregulates cellular proliferation, extracellular matrix protein production, and collagen deposition in human aortic valve interstitial cells through the Trk-Akt (显示 AKT1 抗体)-cyclin D1 (显示 CCND1 抗体) cascade.

  3. NTRK1 gene fusion in spitzoid neoplasms results in tumors with Kamino bodies and were typically arranged in smaller nests with smaller predominantly spindle-shaped cells, occasionally forming rosettes.

  4. expression levels of tropomyosin 3 (TPM3 (显示 TPM3 抗体)) were higher in stage III ESCC tissue compared with stage I (P<0.05). The findings of the present study identified twelve proteins, which are closely associated with ESCC invasion and metastasis, apoptosis and cell signal transduction.

  5. Results suggest that NTRK1 oncogenic activation through gene fusion defines a novel and distinct subset of soft tissue tumors resembling lipofibromatosis (LPF), but displaying cytologic atypia and a neural immunophenotype, provisionally named LPF-like neural tumors.

  6. This review highlights treatment options, including clinical trials for ROS1 rearrangement, RET fusions, NTRK1 fusions, MET exon skipping, BRAF mutations, and KRAS mutations.

  7. ShcD (显示 SHC4 抗体) binds to active Ret (显示 RET 抗体), TrkA, and TrkB (显示 NTRK2 抗体) neurotrophic factor (显示 NTF3 抗体) receptors predominantly via its phosphotyrosine-binding (PTB (显示 PTBP1 抗体)) domain.

  8. Based on these current developments, the present review provides not only a broad overview of the biological effects of NGF-TrkA-p75NTR on cancer cells and their microenvironment, but also explains why NGF and its receptors are going to evoke major interest as promising therapeutic anti-cancer targets in the coming decade.

  9. TrkA misfolding and aggregation induced by some Insensitivity to Pain with Anhidrosis mutations disrupt the autophagy homeostasis causing neurodegeneration.

  10. USP36 (显示 USP36 抗体) actions extend beyond TrkA because the presence of USP36 (显示 USP36 抗体) interferes with Nedd4-2 (显示 NEDD4L 抗体)-dependent Kv7.2 (显示 KCNQ2 抗体)/3 channel regulation.

Mouse (Murine) Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) interaction partners

  1. These findings suggest that by interacting with PlexA4 (显示 PLXNA4 抗体), TrkA plays a crucial role in redirecting local Sema3A (显示 SEMA3A 抗体) signaling to retrograde axonal transport, thereby regulating dendritic GluA2 (显示 GRIA2 抗体) localization and patterning.

  2. proposal that KIF1A (显示 KIF1A 抗体) is essential for the survival and function of sensory neurons because of the TrkA transport and its synergistic support of the NGF (显示 NGFB 抗体)/TrkA/PI3K signaling pathway

  3. As a result, overexpression of PTP (显示 SLC25A3 抗体)-MEG2 (显示 PTPN9 抗体) down-regulates NGF (显示 NGFB 抗体)/TrkA signaling and blocks neurite outgrowth and differentiation

  4. TrkA misfolding and aggregation induced by some Insensitivity to Pain with Anhidrosis mutations disrupt the autophagy homeostasis causing neurodegeneration.

  5. USP36 (显示 USP36 抗体) actions extend beyond TrkA because the presence of USP36 (显示 USP36 抗体) interferes with Nedd4-2 (显示 NEDD4L 抗体)-dependent Kv7.2 (显示 KCNQ2 抗体)/3 channel regulation.

  6. functional PAP (显示 ASAP1 抗体)(thorn) neurons are essential for the analgesic effect, which is mediated by NGF (显示 NGFB 抗体)-trkA signaling.

  7. Dimeric dipeptide mimetics of the nerve growth factor Loop 4 and Loop 1 activate TRKA with different patterns of intracellular signal transduction.

  8. Data show that lysophosphatidic acid (LPA) induces phosphorylation of trkA receptor (TrkA) through lysophosphatidic acid receptor 1 (LPA1 (显示 LPAR1 抗体)) binding to TrkA

  9. adult homozygous TrkAC knock-in mice displayed severe deficits in acute and tissue injury-induced pain, representing the first viable adult Trk mouse mutant with a pain phenotype

  10. IL-6 (显示 IL6 抗体) may act as a new potential cumulus expansion-related transcript, which may be involved in the integration of TrkA and EGF (显示 EGF 抗体) signaling in affecting expansion of cumulus oocyte complexes.

TRKA (NTRK1) 抗原简介

Antigen Summary

This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TRKA (NTRK1)

  • neurotrophic tyrosine kinase, receptor, type 1 (ntrk1) 抗体
  • neurotrophic tyrosine kinase, receptor, type 1 (NTRK1) 抗体
  • neurotrophic tyrosine kinase, receptor, type 1 (LOC100354292) 抗体
  • neurotrophic tyrosine kinase, receptor, type 1 (Ntrk1) 抗体
  • tropomyosin 3 (TPM3) 抗体
  • C80751 抗体
  • CAPM1 抗体
  • CFTD 抗体
  • CTRKA 抗体
  • hscp30 抗体
  • MTC 抗体
  • NEM1 抗体
  • OK/SW-cl.5 抗体
  • p140-TrkA 抗体
  • Tkr 抗体
  • TM-5 抗体
  • TM3 抗体
  • TM5 抗体
  • TM30 抗体
  • TM30nm 抗体
  • TPMsk3 抗体
  • Trk 抗体
  • Trk-A 抗体
  • TRK1 抗体
  • trkA 抗体

Protein level used designations for NTRK1

high affinity nerve growth factor receptor , tyrosine kinase receptor A , neurotrophic tyrosine kinase, receptor, type 1 , high affinity nerve growth factor receptor-like , tropomyosin-related kinase A , Oncogene TRK , TRK1-transforming tyrosine kinase protein , gp140trk , TrkA neurotrophin receptor , p140-TrkA , slow nerve growth factor receptor , trk , trk-A , trkA proto-oncogene receptor , neurotrophic tyrosine kinase receptor type 1 , tropomyosin receptor kinase , alpha-tropomyosin, slow skeletal , cytoskeletal tropomyosin TM30 , heat-stable cytoskeletal protein 30 kDa , tropomyosin alpha-3 chain , tropomyosin gamma , tropomyosin-5

GENE ID SPECIES
30546 Danio rerio
719670 Macaca mulatta
100064594 Equus caballus
100452269 Pongo abelii
100474165 Ailuropoda melanoleuca
457408 Pan troglodytes
490404 Canis lupus familiaris
100354292 Oryctolagus cuniculus
100585466 Nomascus leucogenys
100618744 Monodelphis domestica
4914 Homo sapiens
18211 Mus musculus
59109 Rattus norvegicus
353111 Bos taurus
396337 Gallus gallus
7170 Homo sapiens
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