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SOS1 抗体

(Son of Sevenless Homolog 1 (SOS1))
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008].
SOS1 抗体  (AA 1140-1281) SOS1 抗体  (AA 1140-1281) SOS1 抗体 (AA 1140-1281) (ABIN7170318)

SOS1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated

SOS1 抗体  (AA 313-420) SOS1 抗体  (AA 313-420) SOS1 抗体 (AA 313-420) (ABIN520376)

SOS1 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 4C1 unconjugated

SOS1 抗体 SOS1 抗体 SOS1 抗体 (ABIN535287)

SOS1 适用: 人, 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal SOS-01 unconjugated

SOS1 抗体 by 适用

Find SOS1 抗体 for a variety of species such as anti-Human SOS1, anti-Mouse SOS1, anti-Horse SOS1. The species listed below are among those available. Click on a link to go to the corresponding products.

SOS1 抗体 by 应用范围

Find SOS1 抗体 validated for a specific application such as WB, ELISA, IF, IP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SOS1 抗体 by 抗体来源

Find SOS1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SOS1 抗体 by 抗原表位

Find SOS1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SOS1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SOS1 抗体. Click on a link to go to the corresponding products.

SOS1 抗体 by 克隆

Find SOS1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

SOS1 抗体 by 标记

Find SOS1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SOS1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (4)
Cat. No. ABIN7170318
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, PLA
Validations
  • (4)
Cat. No. ABIN520376
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, ICC
Validations
  • (3)
  • (2)
Cat. No. ABIN535287
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, EIA
Validations
  • (3)
Cat. No. ABIN238504
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6244011
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN562955
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN5588539
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN6750497
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6148283
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
Cat. No. ABIN7384167
Quantity 60 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
Cat. No. ABIN6390474
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7170321
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7170320
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7170319
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF
Validations
Cat. No. ABIN7119340
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SOS1 抗体

Harris, Parry, Westwick, Ward: "Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes." in: The Journal of biological chemistry, Vol. 283, Issue 5, pp. 2465-9, (2008) (PubMed).

Bernards, Settleman: "GEFs in growth factor signaling." in: Growth factors (Chur, Switzerland), Vol. 25, Issue 5, pp. 355-61, (2008) (PubMed).

McDonald, Seldeen, Deegan, Farooq: "Structural basis of the differential binding of the SH3 domains of Grb2 adaptor to the guanine nucleotide exchange factor Sos1." in: Archives of biochemistry and biophysics, Vol. 479, Issue 1, pp. 52-62, (2008) (PubMed).

Xing, Hamaguchi: "Effects of SHIP-1 on MMP2 secretion and invasion of SR3Y1 cells." in: Journal of genetics and genomics = Yi chuan xue bao, Vol. 34, Issue 4, pp. 285-93, (2007) (PubMed).

Tarasenko, Kole, Chi, Mentink-Kane, Wynn, Bolland: "T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 27, pp. 11382-7, (2007) (PubMed).

Furuta, Miura, Copeland, Shang, Oshima, Kamata: "Light Chain 3 associates with a Sos1 guanine nucleotide exchange factor: its significance in the Sos1-mediated Rac1 signaling leading to membrane ruffling." in: Oncogene, Vol. 21, Issue 46, pp. 7060-6, (2002) (PubMed).

Kardinal, Konkol, Lin, Eulitz, Schmidt, Estrov, Talpaz, Arlinghaus, Feller: "Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes." in: Blood, Vol. 98, Issue 6, pp. 1773-81, (2001) (PubMed).

Salojin, Zhang, Meagher, Delovitch: "ZAP-70 is essential for the T cell antigen receptor-induced plasma membrane targeting of SOS and Vav in T cells." in: The Journal of biological chemistry, Vol. 275, Issue 8, pp. 5966-75, (2000) (PubMed).

Scita, Tenca, Frittoli, Tocchetti, Innocenti, Giardina, Di Fiore: "Signaling from Ras to Rac and beyond: not just a matter of GEFs." in: The EMBO journal, Vol. 19, Issue 11, pp. 2393-8, (2000) (PubMed).

Buday, Downward: "Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor." in: Cell, Vol. 73, Issue 3, pp. 611-20, (1993) (PubMed).

Aliases for SOS1 抗体

SOS Ras/Rac guanine nucleotide exchange factor 1 (SOS1) 抗体
son of sevenless homolog 1 (Drosophila) (Sos1) 抗体
SOS Ras/Rac guanine nucleotide exchange factor 1 (Sos1) 抗体
4430401P03Rik 抗体
9630010N06 抗体
AI449023 抗体
GF1 抗体
GGF1 抗体
GINGF 抗体
HGF 抗体
NS4 抗体
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