anti-人 NFATC1 抗体 for Flow Cytometry

Recommended NFATC1 Antibody (supplied by: Log in to see )

抗原
Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) 抗体
  • nf-atc
  • nfat2
  • nfatc
  • si:ch211-198c22.2
  • NFATC1
  • 2210017P03Rik
  • AI449492
  • AV076380
  • NF-ATc
  • NFAT2
  • NFATc
  • Nfatcb
  • NF-ATC
  • NF-ATc1
  • NFAT
  • NFATmac
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
  • NFATC1
  • nfatc1
  • Nfatc1
抗原表位
AA 197-304
29
20
15
14
13
7
6
6
6
5
5
4
2
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠, 大鼠
152
55
39
10
7
7
7
5
4
4
3
3
1
1
1
1
1
宿主
小鼠
105
46
1
克隆类型
单克隆
标记
This NFATC1 antibody is conjugated to Alexa Fluor 488
5
4
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Flow Cytometry (FACS), Mass Cytometry (CyTOF)
124
53
48
16
13
11
11
9
6
4
3
3
2
2
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

产品编号 ABIN2657092
产品在该地区无法提供。
获取报价
中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.368205 ABIN2662815 FACS PE Mouse IgG1 AA 197-304 Log in to see 7A6 7
1 ABIN2666355 FACS Mouse IgG1 AA 197-304 Log in to see 7A6 8
1 ABIN2657093 FACS CyTOF Alexa Fluor 488 Mouse IgG1 AA 197-304 Log in to see 7A6 7
1 ABIN2662816 FACS PE Mouse IgG1 AA 197-304 Log in to see 7A6 7
1 ABIN2666356 FACS Mouse IgG1 AA 197-304 Log in to see 7A6 8
1 ABIN233537 GS ICC FACS IP WB Mouse IgG1 AA 1-654 Log in to see

引用最多的anti-NFATC1 抗体 for Flow Cytometry

Similar anti-NFATC1 抗体

应用范围 / 适用 小鼠 大鼠
Immunofluorescence (fixed cells) (IF/ICC) 2 抗体 1 抗体 1 抗体
Simple Western (SimWes) 2 抗体 2 抗体
Western Blotting (WB) 124 抗体 34 抗体 21 抗体
Mass Cytometry (CyTOF) 2 抗体 2 抗体 2 抗体
Immunoprecipitation (IP) 11 抗体 5 抗体 2 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 16 抗体 5 抗体 4 抗体
Immunohistochemistry (IHC) 48 抗体 18 抗体 14 抗体

General

抗原 Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) 抗体
抗原表位 AA 197-304
(29), (20), (15), (14), (13), (7), (6), (6), (6), (5), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 人, 小鼠, 大鼠
(152), (55), (39), (10), (7), (7), (7), (5), (4), (4), (3), (3), (1), (1), (1), (1), (1)
宿主 小鼠
(105), (46), (1)
克隆类型 (克隆位点)
单克隆   ( )
标记 This NFATC1 antibody is conjugated to Alexa Fluor 488
(5), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Flow Cytometry (FACS), Mass Cytometry (CyTOF)
(124), (53), (48), (16), (13), (11), (11), (9), (6), (4), (3), (3), (2), (2), (2), (1), (1)
Pubmed 7个引用可参考
Supplier Log in to see

NFATC1抗体详情

NFATC1目标详情 使用细节 贮存及处理 ProductDetails: References for anti-NFATC1 antibody (ABIN2657092) 图像
纯化方法 The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
克隆位点 7A6
亚型 IgG1

NFATC1目标详情

NFATC1抗体详情 使用细节 贮存及处理 ProductDetails: References for anti-NFATC1 antibody (ABIN2657092) 图像 回页首
抗原
别名 NFATc1 (NFATC1 Antibody 摘要)
背景 The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. The protein complex consists of NFAT1, NFAT2 (NFATc1 or NFATc), NFAT3, and NFAT4. All members of this family are transcription factors with a Rel homology domain and regulate gene transcription in concert with AP-1 (Jun/Fos) to orchestrate an effective immune response. NFAT proteins are predominantly expressed in cells of the immune system but are also expressed in skeletal muscle, keratinocytes and adipocytes, regulating cell differentiation programs in these cells. In resting cells, NFAT proteins are heavily phosphorylated and localized in the cytoplasm. Increased intracellular calcium concentrations activate the calcium/calmodulin-dependent serine phosphatase calcineurin, which dephosphorylates NFAT proteins, resulting in their subsequent translocation to the nucleus. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
研究领域 Signaling
途径 RTK signaling, WNT signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway

使用细节

NFATC1抗体详情 NFATC1目标详情 贮存及处理 ProductDetails: References for anti-NFATC1 antibody (ABIN2657092) 图像 回页首
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用

贮存及处理

NFATC1抗体详情 NFATC1目标详情 使用细节 ProductDetails: References for anti-NFATC1 antibody (ABIN2657092) 图像 回页首
浓度 0.5 mg/mL
缓冲液 Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Protect from prolonged exposure to light. Do not freeze.
储存条件 4 °C
储存方法 The antibody solution should be stored undiluted between 2°C and 8°C

ProductDetails: References for anti-NFATC1 antibody (ABIN2657092)

NFATC1抗体详情 NFATC1目标详情 使用细节 贮存及处理 图像 回页首
背景

Zhao, Wang, Liu, He, Jia: "NFATc1: functions in osteoclasts." in: The international journal of biochemistry & cell biology, Vol. 42, Issue 5, pp. 576-9, 2010

Brandt, Liman, Bendfeldt, Mueller, Reinke, Radbruch, Worm, Baumgrass: "Whole blood flow cytometric measurement of NFATc1 and IL-2 expression to analyze cyclosporine A-mediated effects in T cells." in: Cytometry. Part A : the journal of the International Society for Analytical Cytology, Vol. 77, Issue 7, pp. 607-13, 2010

Serfling, Berberich-Siebelt, Avots: "NFAT in lymphocytes: a factor for all events?" in: Science's STKE : signal transduction knowledge environment, Vol. 2007, Issue 398, pp. pe42, 2007

Hogan, Chen, Nardone, Rao: "Transcriptional regulation by calcium, calcineurin, and NFAT." in: Genes & development, Vol. 17, Issue 18, pp. 2205-32, 2003

Timmerman, Healy, Ho, Chen, Goodnow, Crabtree: "Redundant expression but selective utilization of nuclear factor of activated T cells family members." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 6, pp. 2735-40, 1997

Hoey, Sun, Williamson, Xu: "Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins." in: Immunity, Vol. 2, Issue 5, pp. 461-72, 1995

Northrop, Ullman, Crabtree: "Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex." in: The Journal of biological chemistry, Vol. 268, Issue 4, pp. 2917-23, 1993

图像

NFATC1抗体详情 NFATC1目标详情 使用细节 贮存及处理 ProductDetails: References for anti-NFATC1 antibody (ABIN2657092) 回页首
厂商提供的图像
Flow Cytometry (FACS) image for anti-NFATC1 抗体 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1) (AA 197-304) (Alexa Fluor 488) (ABIN2657092) anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (AA 197-304) antibody (Alexa Fluor 488)