anti-KIT (KIT) 抗体产品概述

Full name:
anti-V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog 抗体 (KIT)
在www.antibodies-online.cn可供3 V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT) 抗体的2不同的供货商。 再加上,我们可以发KIT 试剂盒 (5)和数多这个蛋白质的别的产品。 总共9 KIT产品已列进来了。
别名:
C-Kit, CD117, KIT, krk1, LOC100221238, MGF, PBT, SCFR, xkl-1, XKrk1
列出全部抗体 基因 基因ID UniProt
大鼠 KIT KIT 64030  
KIT 3815 P10721

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更多抗KIT的相互作用对抗体

Horse (Equine) V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT) interaction partners

  1. the missense mutation p.Arg682His, the g.77784972T>C variant at KIT and the g.20147039C>T variant at MITF (显示 MITF 抗体) are the main influence on the extent of white facial markings

  2. Accumulating mutations in series of haplotypes at the KIT and MITF (显示 MITF 抗体) loci are major determinants of white markings in Franches-Montagnes horses.

Cow (Bovine) V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT) interaction partners

  1. FGF7 (显示 FGF7 抗体) may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG (显示 KITLG 抗体) signaling pathway.

Goat V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT) interaction partners

  1. c-kit is primarily expressed in the spermatogonia and spermatocytes of goat testes.

Pig (Porcine) V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT) interaction partners

  1. mRNA expression of c-kit and SCF was decreased in gallbladder tissues in the HCD group. Consistent with the findings of RT-PCR, a lower expression level of c-kit and SCF protein was also observed in HCD animals.

  2. Delayed enrichment for c-kit and inducing cardiac differentiation attenuated protective effects of BMSCs' transplantation in pig model of acute myocardial infarction.

  3. Pravastatin improves function in hibernating myocardium by mobilizing CD133+ and cKit+ bone marrow progenitor cells and promoting myocytes to reenter the growth phase of the cardiac cell cycle.

Human V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT) interaction partners

  1. c-KIT overexpressing cells showed a regression of typical morphological features of malignancy. Taken together these results suggest that c-KIT could be involved in the differentiation of thyroid cells and in tumor progression

  2. low level of MITF (显示 MITF 抗体) cooperates with oncogenic KIT to transform melanocytes. Activation of the cAMP pathway in transformed (L576P)KIT melanocytes stimulated MITF (显示 MITF 抗体) expression, and reduced cellular proliferation and sphere formation. These findings highlight the essential role of MITF (显示 MITF 抗体) in revealing the oncogenic activity of KIT in melanocytes and suggest that the cAMP pathway is a therapeutic target in KIT-mutated melanoma.

  3. This previously unexplored G4-G4 interaction modulates both the conformation and the stability of the overall arrangement of the c-KIT promoter. It is not supported by stacking of single nucleotides but refers to a G4-G4 interaction surface surrounded by a two-nucleotides loop that might represent a reliable unprecedented target for anticancer therapy.

  4. Transcription factor-induced activation of cardiac gene expression in human c-kit+ cardiac progenitor cells has been reported.

  5. It was found that the absence of mutations in the SRSF2 (显示 SRSF2 抗体), ASXL1 (显示 ASXL1 抗体), and/or RUNX1gene panel at baseline and a reduction of the KIT D816V allele burden more than 25% at month 6 are the most favorable predictors for improved survival in midostaurin-treated advanced systemic mastocytosis patients.

  6. Point mutation in c-kit gene is associated with sequential development of an ovarian mixed germ cell tumor and systemic mastocytosis with chronic myelomonocytic leukemia.

  7. This study assesses MYB (显示 MYB 抗体), CD117 and SOX-10 (显示 SOX10 抗体) expression in cutaneous adnexal tumors.

  8. EGFR (显示 EGFR 抗体) expression was observed in 58% and c-KIT expression was seen in 30% of the cases [triple negative breast cancer]

  9. Canonical TGF-beta (显示 TGFB1 抗体) and c-KIT signaling forms a positive, tumor-promoting feedback loop. Disruption of this loop restores TGF-beta (显示 TGFB1 抗体) tumor suppressor function and provides the rationale for targeting the TGF-beta (显示 TGFB1 抗体)/SCF (显示 KITLG 抗体) axis as a novel therapeutic strategy for Hepatocellular carcinoma.

  10. We conclude that c-KIT expression is a valuable predictor of prognosis and survival, especially in thick (>4 mm) vulvar melanomas

KIT 抗原简介

Antigen Summary

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with KIT

  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (Kit) 抗体
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT) 抗体
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (kit-a) 抗体
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (kit) 抗体
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (LOC100221238) 抗体
  • C-Kit 抗体
  • CD117 抗体
  • KIT 抗体
  • krk1 抗体
  • LOC100221238 抗体
  • MGF 抗体
  • PBT 抗体
  • SCFR 抗体
  • xkl-1 抗体
  • XKrk1 抗体

Protein level used designations for KIT

c-kit receptor tyrosine kinase , mast/stem cell growth factor receptor , protein kinase , tyrosine kinase receptor homolog , c-kit-related protein , kit-related kinase 1 , mast/stem cell growth factor receptor-related protein Kit , proto-oncogene tyrosine-protein kinase Kit-related protein , tyrosine-protein kinase Kit , v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog , Mast/stem cell growth factor receptor , mast/stem cell growth factor receptor Kit , c-kit , transmembrane tyrosine kinase receptor , proto-oncogene c-Kit , SCFR , c-kit receptor , mast cell growth factor receptor , proto-oncogene tyrosine-protein kinase Kit , receptor tyrosine kinase c-kit , c-KIT gene1 , Proto-oncogene c-Kit , Tyrosine-protein kinase Kit , caprine c-kit protein , p145 c-kit , piebald trait protein , soluble KIT variant 1 , v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

GENE ID SPECIES
64030 Rattus norvegicus
100009704 Equus caballus
373579 Xenopus laevis
461316 Pan troglodytes
696759 Macaca mulatta
780504 Ovis aries
100075317 Ornithorhynchus anatinus
100216090 Xenopus (Silurana) tropicalis
100221238 Taeniopygia guttata
100327263 Oryctolagus cuniculus
100411615 Callithrix jacchus
100603893 Nomascus leucogenys
280832 Bos taurus
493766 Felis catus
378783 Gallus gallus
403811 Canis lupus familiaris
100861386 Capra hircus
396810 Sus scrofa
3815 Homo sapiens
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