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FLT3 抗体

(Fms-Related tyrosine Kinase 3 (FLT3))
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jul 2008].
FLT3 抗体  (AA 930-991) FLT3 抗体  (AA 930-991) FLT3 抗体 (AA 930-991) (ABIN1724846)

FLT3 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 7B7C3 unconjugated

FLT3 抗体  (AA 62-295) FLT3 抗体  (AA 62-295) FLT3 抗体 (AA 62-295) (ABIN5518988)

FLT3 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

FLT3 抗体 FLT3 抗体 FLT3 抗体 (ABIN7012052)

FLT3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

FLT3 抗体 by 适用

Find FLT3 抗体 for a variety of species such as anti-Human FLT3, anti-Mouse FLT3, anti-Rat FLT3. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find FLT3 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

FLT3 抗体 by 抗体来源

Find FLT3 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

FLT3 抗体 by 抗原表位

Find FLT3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

FLT3 抗体 by 克隆形成能力

Find available monoclonal or polyclonal FLT3 抗体. Click on a link to go to the corresponding products.

FLT3 抗体 by 克隆

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Find FLT3 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular FLT3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
  • (4)
Cat. No. ABIN1724846
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (6)
Cat. No. ABIN5518988
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7012052
Quantity 60 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7430516
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7443014
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (5)
Cat. No. ABIN3030975
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6261770
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS
Validations
  • (1)
  • (2)
Cat. No. ABIN1302921
Quantity 100 tests
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6140691
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS
Validations
  • (1)
  • (2)
Cat. No. ABIN489931
Quantity 100 tests
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN391981
Quantity 400 μL
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN684868
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (2)
Cat. No. ABIN947874
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Horse, Human, Monkey, Pig, Rabbit
Application IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1048600
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application FACS, IP
Validations
  • (2)
Cat. No. ABIN457417
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our FLT3 抗体

Caldarelli, Müller, Paskowski-Rogacz, Herrmann, Bauer, Koch, Heninger, Krastev, Ding, Kasper, Fischer, Brodhun, Böhmer, Buchholz: "A genome-wide RNAi screen identifies proteins modulating aberrant FLT3-ITD signaling." in: Leukemia, Vol. 27, Issue 12, pp. 2301-10, (2013) (PubMed).

Pereira de Sousa, Berthault, Granato, Dias, Ramond, Kee, Cumano, Vieira: "Inhibitors of DNA binding proteins restrict T cell potential by repressing Notch1 expression in Flt3-negative common lymphoid progenitors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 8, pp. 3822-30, (2012) (PubMed).

How, Sykes, Gupta, Yee, Schimmer, Schuh, Minden, Kamel-Reid, Brandwein: "Influence of FLT3-internal tandem duplication allele burden and white blood cell count on the outcome in patients with intermediate-risk karyotype acute myeloid leukemia." in: Cancer, Vol. 118, Issue 24, pp. 6110-7, (2012) (PubMed).

Williams, Li, Nguyen, Brown, Levis, Small: "Fluvastatin inhibits FLT3 glycosylation in human and murine cells and prolongs survival of mice with FLT3/ITD leukemia." in: Blood, Vol. 120, Issue 15, pp. 3069-79, (2012) (PubMed).

Ninagawa, Murakami, Isobe, Tanaka, Nakagawa, Torihashi: "Mesenchymal stem cells originating from ES cells show high telomerase activity and therapeutic benefits." in: Differentiation; research in biological diversity, Vol. 82, Issue 3, pp. 153-64, (2011) (PubMed).

Arora, Stopp, Böhmer, Schons, Godfrey, Masson, Razumovskaya, Rönnstrand, Tänzer, Bauer, Böhmer, Müller: "Protein-tyrosine phosphatase DEP-1 controls receptor tyrosine kinase FLT3 signaling." in: The Journal of biological chemistry, Vol. 286, Issue 13, pp. 10918-29, (2011) (PubMed).

Sekine, Kataoka, Fukuyama, Adachi, Davydova, Yamamoto, Kobayashi, Fujihashi, Suzuki, Curiel, Shizukuishi, McGhee, Fujihashi: "A novel adenovirus expressing Flt3 ligand enhances mucosal immunity by inducing mature nasopharyngeal-associated lymphoreticular tissue dendritic cell migration." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 12, pp. 8126-34, (2008) (PubMed).

Al Shaer, Walsby, Gilkes, Tonks, Walsh, Mills, Burnett, Rowntree: "Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling." in: British journal of haematology, Vol. 141, Issue 4, pp. 483-93, (2008) (PubMed).

Pratz, Levis: "Incorporating FLT3 inhibitors into acute myeloid leukemia treatment regimens." in: Leukemia & lymphoma, Vol. 49, Issue 5, pp. 852-63, (2008) (PubMed).

Ravandi, Jilani, Estey, Kantarjian, Dey, Aguilar, Jitkaroon, Giles, OBrien, Keating, Albitar: "Soluble phosphorylated fms-like tyrosine kinase III. FLT3 protein in patients with acute myeloid leukemia (AML)." in: Leukemia research, Vol. 31, Issue 6, pp. 791-7, (2007) (PubMed).

Aliases for FLT3 抗体

fms related tyrosine kinase 3 (FLT3) 抗体
FMS-like tyrosine kinase 3 (Flt3) 抗体
fms-related tyrosine kinase 3 (Flt3) 抗体
fms related tyrosine kinase 3 (Flt3) 抗体
B230315G04 抗体
CD135 抗体
Flk-2 抗体
FLK-2 抗体
Flk2 抗体
FLK2 抗体
Flt-3 抗体
FLT3 抗体
Ly72 抗体
STK1 抗体
wmfl 抗体
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