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anti-FLT1 (FLT1) 抗体产品概述

Full name:
anti-Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) 抗体 (FLT1)
在www.antibodies-online.cn可供458 Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) 抗体的36不同的供货商。 再加上,我们可以发FLT1 蛋白 (70)FLT1 试剂盒 (63)和数多这个蛋白质的别的产品。 总共612 FLT1产品已列进来了。
别名:
AI323757, FLT, FLT-1, FLT1, flt1b, sFlt1, VEGFR-1, VEGFR1

所有可销售的anti-FLT1 抗体

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引用最多的anti-FLT1 抗体

  1. Human Monoclonal FLT1 Primary Antibody for FACS - ABIN4897100 : Karrar, Broomé, Uzunel, Qureshi, Sumitran-Holgersson: Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction. in Gut 2007 (PubMed)
    Show all 16 references for ABIN4897100

  2. Human Monoclonal FLT1 Primary Antibody for FACS - ABIN4897099 : de Groot, Piao, Tran, Gilbert, Wu, Liu, Bekele, Cloughesy, Mehta, Robins, Lassman, DeAngelis, Camphausen, Chen, Yung, Prados, Wen, Heymach: Myeloid biomarkers associated with glioblastoma response to anti-VEGF therapy with aflibercept. in Clinical cancer research : an official journal of the American Association for Cancer Research 2011 (PubMed)
    Show all 5 references for ABIN4897099

  3. Mouse (Murine) Monoclonal FLT1 Primary Antibody for FACS - ABIN4897107 : Reddy, Zhou, Schadler, Jia, Kleinerman: Bone marrow subsets differentiate into endothelial cells and pericytes contributing to Ewing's tumor vessels. in Molecular cancer research : MCR 2008 (PubMed)
    Show all 2 references for ABIN4897107

  4. Mouse (Murine) Monoclonal FLT1 Primary Antibody for FACS - ABIN4897105 : Fang, Wei, Pentinmikko, Leinonen, Salven: Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. in PLoS biology 2012 (PubMed)
    Show all 2 references for ABIN4897105

  5. Human Polyclonal FLT1 Primary Antibody for IHC (p), WB - ABIN115391 : Ahmed, Li, Dunk, Whittle, Rushton, Rollason: Colocalisation of vascular endothelial growth factor and its Flt-1 receptor in human placenta. in Growth factors (Chur, Switzerland) 1996 (PubMed)
    Show all 2 references for ABIN115391

  6. Human Polyclonal FLT1 Primary Antibody for IHC, ELISA - ABIN1532085 : Shibuya, Yamaguchi, Yamane, Ikeda, Tojo, Matsushime, Sato: Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. in Oncogene 1990 (PubMed)

  7. Human Polyclonal FLT1 Primary Antibody for EIA, FACS - ABIN955511 : Wong, Buckman, Clemons, Verma, Dent, Trudeau, Roche, Ebos, Kerbel, Deboer, Sutherland, Emmenegger, Slingerland, Gardner, Pritchard: Phase I/II trial of metronomic chemotherapy with daily dalteparin and cyclophosphamide, twice-weekly methotrexate, and daily prednisone as therapy for metastatic breast cancer using vascular endothelial growth factor and soluble vascular endothelial growt in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010 (PubMed)

  8. Human Polyclonal FLT1 Primary Antibody for IHC (p) - ABIN373446 : Hohenstein, Colin, Foellmer, Amann, Brekken, Daniel, Hugo: Autocrine VEGF-VEGF-R loop on podocytes during glomerulonephritis in humans. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010 (PubMed)

更多抗FLT1的相互作用对抗体

Mouse (Murine) Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. First-in-class selective PET tracers for imaging VEGFR-1 and VEGFR-2 (显示 KDR 抗体) were constructed and successfully validated in an orthotopic murine tumor model.

  2. these results suggest that VEGFR1 signaling plays a role in regulating the balance between macrophage phenotypes in streptozotocin -induced diabetic wounds, prevents impaired diabetic wound healing, and promotes angiogenesis/lymphangiogenesis.

  3. These data therefore support a tightly controlled, paracrine signaling mechanism of VEGF-B (显示 VEGFB 抗体) to VEGFR1.

  4. Flt1/VEGF-A (显示 VEGFA 抗体) signalling has stage-specific effects on vascular morphogenesis.

  5. IL-35 treatment reduced collagen-induced arthritis via inhibiting vascular endothelial growth factor and its receptors

  6. the VEGFR-1 tyrosine kinase (显示 TYRO3 抗体) signaling has an effect on angiogenesis.

  7. data suggest that sFlt-1 may have a therapeutic effect on AS, resulting from suppression of VEGF signaling-mediated recruitment of circulating monocytes/macrophages

  8. that Flt-1 plays a critical role in cardiac hypertrophy induced by pressure overload via the activation of AKT (显示 AKT1 抗体)

  9. Flt-1 appears to play a role in oxidative stress, which promotes apoptosis of trophoblasts

  10. This article reviews the current evidence on the clinical utility of the sFlt-1/PlGF (显示 PGF 抗体) ratio at different points in pregnancy and, accordingly, make a proposal for its clinical implementation. [review]

Human Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. this study shows that Fli-1 (显示 FLI1 抗体) plays a major role in the regulation of granulocyte colony stimulating factor (显示 CSF3 抗体)

  2. Patients with post-peripartum cardiomyopathy have significantly higher plasma sFlt1 concentration with a trend of somewhat higher levels of VEGF (显示 VEGFA 抗体) and significantly decreased VEGF (显示 VEGFA 抗体)/sFlt1 ratio compared to controls.

  3. soluble fms-like tyrosine kinase-1 inhibits cell proliferation, migration, and invasion of colorectal cancer SW480 cells through suppression of vascular mimicry formation, which provides a good basis for the development of new drugs for the treatment of colorectal cancer by targeting both angiogenesis and vascular mimicry formation.

  4. a significant association between the expanded disability status scale and sVEGFR1 (beta=0.007; p<0.001). Our findings revealed that circulatory membranous as well as soluble expression of VEGFR1 increases during angiogenic and inflammatory phenomena of MS.

  5. Data suggest that the associations among angiopoietin-2 (显示 ANGPT2 抗体), sFlt-1, coagulation abnormalities and severe course of acute pancreatitis (AP) might be mediated by other bioactive compounds.

  6. The preeclampsia group had higher soluble fms-like tyrosine kinase-1 from >/=28 weeks compared to controls.

  7. A strong, novel prospective association was identified between lower concentrations of soluble Fms (显示 CSF1R 抗体)-like kinase 1 and placental growth factor (显示 PGF 抗体) measured in early pregnancy and spontaneous abortion.

  8. Women with preeclampsia had higher concentrations of soluble Fms-like tyrosine kinase 1 compared with control subjects. There were significant uteroplacental arteriovenous differences of soluble Fms-like tyrosine kinase 1 in preeclampsia, but not in the control subjects.

  9. The rs9508025 in FLT1 was significantly associated with long-term cardiovascular events, particularly in patients with prior coronary artery disease.

  10. VEGFR1 rs9582036 is a candidate predictive biomarker in metastatic clear-cell renal cell carcinoma (显示 MOK 抗体) patients treated with sunitinib.

Cow (Bovine) Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. These results suggest that non-dominant follicles maintain a greater concentration of the mRNA expression of both membrane and soluble VEGF receptors; but follicular dominance is related to a reduction in the mRNA expression of sVEGFR1 and sVEGFR2.

  2. VEGFR-1 negatively regulates primary bovine retinal pericytes survival, and its blockade protects the blood-brain barrier integrity.

  3. gamma-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1

  4. VEGFR1 mRNA expression was lower at estrus and at the early I and early II luteal stages than at the other stages, whereas VEGFR1 protein expression did not change significantly throughout the estrous cycle (P<0.05)

  5. Alterations in the expression of VEGF-A (显示 VEGFA 抗体) and bFGF (显示 FGF2 抗体) systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.

  6. inhibition of VEGFR-1 results in decrease in number of capillary connections indicating VEGFR-1 ligands promote branching angiogenesis.

  7. TGF-beta1 (显示 TGFB1 抗体) induction of VEGFR-1 in endothelial cells explains pericyte protection of vessels and the selective vulnerability of neonatal vessels to oxygen(VEGFR-1)

  8. the activation of VEGFR-1 and VEGFR-2 (显示 KDR 抗体) heterodimer (VEGFR-1/R-2) is essential for PGI(2 (显示 PTGIR 抗体)) synthesis mediated by VEGF-A (显示 VEGFA 抗体)(165) and VEGF-A (显示 VEGFA 抗体)(121), which cannot be reproduced by the parallel activation of VEGFR-1 and VEGFR-2 (显示 KDR 抗体) homodimers with corresponding agonists

  9. PEDF (显示 SERPINF1 抗体) and VEGFR-1 have roles in the negative regulation of angiogenesis

Pig (Porcine) Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. we analyzed the expression and cellular distribution of Flt-1(VEGFR-1) and Flk-1 (KDR/VEGFR-2 (显示 KDR 抗体))in newborn piglet brain

  2. data shows that members of the VEGF (显示 VEGFA 抗体)-VEGFR (显示 KDR 抗体) system are temporally and spatially well localized for playing key roles during umbilical cord formation and its intensive growth observed after day 75 of pregnancy

  3. The VEGFR1 was stably expressed during the whole lifespan of mesonephric glomeruli, and VEGFR1 is important for the maintenance of endothelial fenestrations.

  4. increased placental expression of the VEGF receptor system is associated with increased placental vascular density observed with the advancement of gestation in the pig.

  5. EGFR (显示 EGFR 抗体), VEGFR (显示 KDR 抗体) and FGFR (显示 FGFR2 抗体) are expressed in porcine oviduct and endometrium during the time of implantation [review]

  6. VEGF ligand-receptor system may play an important role in the development and maintenance of the corpus luteum in pigs.

  7. VEGF (显示 VEGFA 抗体)/Flk-1 (显示 KDR 抗体)/Flt-1 system is activated during myocardial ischemia reperfusion injury.

  8. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (显示 VEGFA 抗体), pro-MMP-9 (显示 MMP9 抗体), MMP-2 (显示 MMP2 抗体), VEGFR-1, VEGFR-2 (显示 KDR 抗体), and TIMP-1 (显示 TIMP1 抗体), which may contribute to the development of venous stenosis.

  9. in experimental intervertebral disc degeneration, VEGF receptors were expressed in the damaged disc and paradiscal tissues

Zebrafish Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. Flt1-tyrosine kinase (TK) activity contributed significantly in endothelial cells survival and vascular development during embryo angiogenesis in zebrafish by engaging PI3K/Akt (显示 AKT1 抗体) pathway.

  2. Elevated Notch (显示 NOTCH1 抗体) signaling downstream of perturbed VEGF (显示 VEGFA 抗体) signaling contributes to aberrant flt-1(-/-) blood vessel formation.

  3. Data indicate that the increase in FLT1/sFLT1 protein levels upon miR-10 (显示 LILRB2 抗体) knockdown inhibited the angiogenic behavior of endothelial cells largely by antagonizing vascular endothelial growth factor receptor 2 (显示 KDR 抗体) signaling.

FLT1 抗原简介

Antigen Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

Alternative names and synonyms associated with FLT1

  • fms-related tyrosine kinase 1 (FLT1) 抗体
  • vascular endothelial growth factor receptor 1 (CpipJ_CPIJ012087) 抗体
  • FMS-like tyrosine kinase 1 (Flt1) 抗体
  • FMS-related tyrosine kinase 1 (Flt1) 抗体
  • fms-related tyrosine kinase 1 (Flt1) 抗体
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (FLT1) 抗体
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (flt1) 抗体
  • vascular endothelial growth factor receptor-1 (FLT-1) 抗体
  • AI323757 抗体
  • FLT 抗体
  • FLT-1 抗体
  • FLT1 抗体
  • flt1b 抗体
  • sFlt1 抗体
  • VEGFR-1 抗体
  • VEGFR1 抗体

Protein level used designations for FLT1

fms-related tyrosine kinase 1 , vascular endothelial growth factor receptor 1 , embryonic receptor kinase 2 , tyrosine-protein kinase receptor FLT , vascular endothelial growth factor receptor-1 , vascular permeability factor receptor , fms-like tyrosine kinase 1 , fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) , tyrosine-protein kinase FRT , FLT-1 , FMS-like tyrosine kinase 1 , Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) , VEGF-receptor , flt-receptor , vascular endothelial growth factor 1 , vascular endothelial growth factor/vascular permeability factor receptor , ascular endothelial growth factor/vascular permeability factor receptor , VEGFR-1 , flt-1 type VEGF receptor , receptor tyrosine kinase Flt1b , soluble fms-like tyrosine kinase 1

GENE ID SPECIES
443088 Ovis aries
6044537 Culex quinquefasciatus
14254 Mus musculus
2321 Homo sapiens
54251 Rattus norvegicus
100732326 Cavia porcellus
503620 Bos taurus
403727 Canis lupus familiaris
374100 Gallus gallus
396763 Sus scrofa
544667 Danio rerio
443182 Ovis aries
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