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EPHA6, a gene implicated in retinal axon guidance, is one of HMX1 (显示 HMX1 ELISA试剂盒) targets in eye development.
HOXA13 (显示 HOXA13 ELISA试剂盒) directly regulates EphA6 and EphA7 (显示 EPHA7 ELISA试剂盒) in the developing genital tubercle.
These findings suggest that EphA6, in line with a number of other Eph receptors and their ephrin ligands, is involved in neural circuits underlying aspects of learning and memory.
EphA6 mRNA expression is higher in 112 CaP tumor samples compared with benign tissues from 58 benign prostate hyperplasia patients. Positive correlation was identified between EphA6 expression and vascular invasion, neural invasion, PSA (显示 PLAG1 ELISA试剂盒) level, and TNM (显示 ODZ1 ELISA试剂盒) staging in CaP cases.
Two predominant genes, ephrin type A receptor 6 (EPHA6) and folliculin (FLCN (显示 FLCN ELISA试剂盒)), with mutations exclusive to African American CRCs, are by genetic and biological criteria highly likely African American CRC (显示 CALR ELISA试剂盒) driver genes.
During development of the retinal vasculature, migration of ligand-bearing astrocytes is slowed along Eph (显示 EPHA1 ELISA试剂盒)-A6 expression gradient through repellent Eph (显示 EPHA1 ELISA试剂盒)-A6 - ephrin-A1 (显示 EFNA1 ELISA试剂盒) and -A4 signaling.
Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
Eph receptor A6
, EPH receptor A6
, EPH homology kinase 2
, ephrin type-A receptor 6
, tyrosine-protein kinase receptor EHK-2
, EPH-like kinase 12
, ephrin receptor EphA6