anti-小鼠 DDR2 抗体 for Immunohistochemistry (Paraffin-embedded Sections)

Recommended DDR2 Antibody (supplied by: Log in to see )

抗原
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) 抗体
  • DDR2
  • ddr2
  • si:ch211-193c2.1
  • AW495251
  • Ntrkr3
  • tyro10
  • MIG20a
  • NTRKR3
  • TKT
  • TYRO10
  • Tyro10
  • discoidin domain receptor tyrosine kinase 2
  • discoidin domain receptor family, member 2b
  • discoidin domain receptor family, member 2
  • DDR2
  • ddr2b
  • LOC100356982
  • Ddr2
抗原表位
AA 1-399
15
13
12
11
8
6
3
2
2
2
2
2
1
1
1
1
1
1
1
1
适用
小鼠
91
34
5
1
1
宿主

75
40
克隆类型
多克隆
标记
This DDR2 antibody is un-conjugated
4
4
4
4
4
4
2
2
2
2
2
2
2
应用范围
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
85
57
38
22
17
12
5
3
2
1
1
Supplier
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产品编号 ABIN2001101
产品在该地区无法提供。
获取报价
中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.400779 ABIN4304588 FACS IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
13.400779 ABIN4304587 IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN755218 IF (p) IHC (p) WB Rabbit IgG AA 275-320 Log in to see Polyclonal 2
1 ABIN658537 IHC (p) WB Rabbit Ig AA 816-843, C-Term Log in to see Polyclonal
1 ABIN2855418 FACS IHC (p) IHC WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN2855450 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN1811518 IHC (p) WB Rabbit AA 816-843 Log in to see Polyclonal
1 ABIN4901384 ELISA IHC (p) Rabbit IgG Log in to see Polyclonal

引用最多的anti-DDR2 抗体 for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-DDR2 抗体

应用范围 / 适用 小鼠
ELISA 20 抗体
Flow Cytometry (FACS) 2 抗体
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 抗体
Immunohistochemistry (IHC) 20 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 抗体
Western Blotting (WB) 27 抗体

General

抗原 Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) 抗体
抗原表位 AA 1-399
(15), (13), (12), (11), (8), (6), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
适用 小鼠
(91), (34), (5), (1), (1)
宿主
(75), (40)
克隆类型
多克隆
标记 This DDR2 antibody is un-conjugated
(4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2)
应用范围 ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(85), (57), (38), (22), (17), (12), (5), (3), (2), (1), (1)
Pubmed 2个引用可参考
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DDR2抗体详情

DDR2目标详情 使用细节 贮存及处理 ProductDetails: References for anti-DDR2 antibody (ABIN2001101) 图像
特异性 Mouse DDR2
产品特性 Produced in rabbits immunized with purified, recombinant Mouse DDR2 (rM DDR2, ABIN2007949 NP_072075.2, Met 1-Arg 399,. DDR2 specific IgG was purified by Mouse DDR2 affinity chromatography.
纯化方法 purified by affinity chromatography
过滤 0.2 μm filtered
免疫原 Recombinant Mouse DDR2 protein (ABIN2007949)
亚型 IgG

DDR2目标详情

DDR2抗体详情 使用细节 贮存及处理 ProductDetails: References for anti-DDR2 antibody (ABIN2001101) 图像 回页首
抗原
别名 DDR2 (DDR2 Antibody 摘要)
背景 Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2, up-regulates matrix metallloproteinase 1 (MMP-1) and MMP-2 expression in cellular matrix. DDR2/CD167b was found to recognise the triple-helical region of collagen X as well as the NC1 domain. Binding to the collagenous region was dependent on the triple-helical conformation. DDR2/CD167b autophosphorylation was induced by the collagen X triple- helical region but not the NC1 domain, indicating that the triple-helical region of collagen X contains a specific DDR2 binding site that is capable of receptor activation. DDR2/CD167b is induced during stellate cell activation and implicate the phosphorylated receptor as a mediator of MMP-2 release and growth stimulation in response to type I collagen. Moreover, type I collagen-dependent upregulation of DDR2/CD167b expression establishes a positive feedback loop in activated stellate cells, leading to further proliferation and enhanced invasive activity.
NCBI登录号 NP_072075.2
研究领域 Cardiovascular, Cardiogenesis
途径 RTK signaling

使用细节

DDR2抗体详情 DDR2目标详情 贮存及处理 ProductDetails: References for anti-DDR2 antibody (ABIN2001101) 图像 回页首
应用备注 ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse DDR2. The detection limit for Mouse DDR2 is approximately 0.039 ng/well.
IHC-P: 0.1-2 μg/mL
限制 仅限研究用

贮存及处理

DDR2抗体详情 DDR2目标详情 使用细节 ProductDetails: References for anti-DDR2 antibody (ABIN2001101) 图像 回页首
状态 Liquid
缓冲液 0.2 μm filtered solution in PBS with 5 % trehalose
储存液 Without preservative
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 4 °C,-20 °C,-80 °C
储存方法 This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
有效期 12 months

ProductDetails: References for anti-DDR2 antibody (ABIN2001101)

DDR2抗体详情 DDR2目标详情 使用细节 贮存及处理 图像 回页首
背景

Zhang, Ding, Zhang, Su, Li, Liu, Ma, Yao: "Expression of discoidin domain receptor 2 (DDR2) extracellular domain in pichia pastoris and functional analysis in synovial fibroblasts and NIT3T3 cells." in: Molecular and cellular biochemistry, Vol. 290, Issue 1-2, pp. 43-53, 2006

Leitinger, Steplewski, Fertala: "The D2 period of collagen II contains a specific binding site for the human discoidin domain receptor, DDR2." in: Journal of molecular biology, Vol. 344, Issue 4, pp. 993-1003, 2004

图像

DDR2抗体详情 DDR2目标详情 使用细节 贮存及处理 ProductDetails: References for anti-DDR2 antibody (ABIN2001101) 回页首
厂商提供的图像
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-DDR2 抗体 (Discoidin Domain Receptor tyrosine Kinase 2) (AA 1-399) (ABIN2001101) anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 1-399) antibody
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-DDR2 抗体 (Discoidin Domain Receptor tyrosine Kinase 2) (AA 1-399) (ABIN2001101) anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 1-399) antibody (Image 2)