anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) 抗体产品概述

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anti-Squamous Cell Carcinoma Antigen Recognized By T Cells 3 抗体 (SART3)
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别名:
AU045857, DKFZp469J2418, DSAP1, mKIAA0156, P100, p110, p110(nrb), RP11-13G14, SART3, si:ch211-191d15.4, TIP110, wu:fc51h03
列出全部抗体 基因 基因ID UniProt
SART3 9733 Q15020
SART3 53890 Q9JLI8
SART3 304582  

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  1. Dog (Canine) Polyclonal SART3 Primary Antibody for IHC, WB - ABIN2780944 : Liu, Li, Kim, Pace, He: HIV-1 Tat protein-mediated transactivation of the HIV-1 long terminal repeat promoter is potentiated by a novel nuclear Tat-interacting protein of 110 kDa, Tip110. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for 2780944

  2. Cow (Bovine) Polyclonal SART3 Primary Antibody for WB - ABIN2775728 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

  3. Human Polyclonal SART3 Primary Antibody for ELISA, WB - ABIN184889 : Bell, Schreiner, Damianov, Reddy, Bindereif: p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor. in The EMBO journal 2002 (PubMed)

更多抗Squamous Cell Carcinoma Antigen Recognized By T Cells 3的相互作用对抗体

Human Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) interaction partners

  1. We show that PRP31 (显示 PRPF31 抗体), a component of U4 snRNP (显示 LSM2 抗体), is modified with K63-linked ubiquitin chains by the PRP19 (显示 PRPF19 抗体) complex and deubiquitinated by USP15 (显示 USP15 抗体) and its substrate targeting factor SART3. USP15SART3 makes a complex with USP4 (显示 USP4 抗体) and this ternary complex serves as a platform to deubiquitinate PRP31 (显示 PRPF31 抗体) and PRP3 (显示 CLCA4 抗体)

  2. The complex structure of SART3 nuclear localization signal (NLS (显示 ALDH1A2 抗体)) and importin-alpha reveals bipartite binding, and removal of SART3 NLS (显示 ALDH1A2 抗体) prevents the entry of USP4 (显示 USP4 抗体) (and USP15 (显示 USP15 抗体)) into the nucleus and abrogates the subsequent deubiquitinase activity of USP4 (显示 USP4 抗体).

  3. crystal structures of SART3 in the apo (显示 C9orf3 抗体)-form and in complex with the DUSP (显示 DUSP5 抗体)-UBL domain of USP15 (显示 USP15 抗体) at 2.0 and 3.0 A, respectively. Structural analysis reveals SART3 contains 12 half-a-tetratricopeptide (HAT (显示 MGEA5 抗体)) repeats, organized into two subdomains, HAT (显示 MGEA5 抗体)-N and HAT (显示 MGEA5 抗体)-C. SART3 dimerizes through the concave surface of HAT (显示 MGEA5 抗体)-C, whereas the HAT (显示 MGEA5 抗体)-C convex surface binds USP15 (显示 USP15 抗体) in a novel bipartite mode.

  4. miR (显示 MLXIP 抗体)-124 regulates Tip110 expression and differentiation of human cord blood CD34 (显示 CD34 抗体)(+) cells

  5. Hypoxia led to Tip110 protein degradation through the ubiquitin-proteasome system. Under hypoxia, Tip110 stabilized p53 (显示 TP53 抗体), which in return destabilized Tip110.

  6. SART3 recruits ubH2B, which may be evicted from DNA during transcription, for deubiquitination by Usp15 (显示 USP15 抗体)

  7. YB-1 (显示 YBX1 抗体) potentiates the Tip110/Tat (显示 TAT 抗体)-mediated transactivation of the HIV-1 LTR promoter.

  8. findings show C-MYC (显示 MYC 抗体) upregulates transcription of TIP110 through interaction with the TIP110 E-box in the TIP110 promoter, ensuring high-level Tip110 expression in proliferating embryonic stem cells (hESCs); further show TIP110 regulates OCT4 (显示 POU5F1 抗体) alternative splicing in hESCs

  9. TIP110 is also expressed in human embryonic stem cells (hESCs) and expression was decreased with differentiation of these ESCs (显示 NR2E3 抗体).

  10. Results suggest that U4 and U6 small nuclear ribonucleoproteins (snRNPs) accumulate in Cajal bodies for the purpose of assembly into U4/U6 snRNPs by SART3/p110.

Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3) 抗原简介

Antigen Summary

The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.

Alternative names and synonyms associated with Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3)

  • squamous cell carcinoma antigen recognized by T cells 3 (SART3) 抗体
  • squamous cell carcinoma antigen recognized by T cells 3 (sart3) 抗体
  • squamous cell carcinoma antigen recognized by T cells 3 (LOC100354995) 抗体
  • squamous cell carcinoma antigen recognised by T cells 3 (sart3) 抗体
  • squamous cell carcinoma antigen recognized by T cells 3 (Sart3) 抗体
  • squamous cell carcinoma antigen recognized by T-cells 3 (Sart3) 抗体
  • AU045857 抗体
  • DKFZp469J2418 抗体
  • DSAP1 抗体
  • mKIAA0156 抗体
  • P100 抗体
  • p110 抗体
  • p110(nrb) 抗体
  • RP11-13G14 抗体
  • SART3 抗体
  • si:ch211-191d15.4 抗体
  • TIP110 抗体
  • wu:fc51h03 抗体

Protein level used designations for SART3

squamous cell carcinoma antigen recognized by T cells 3 , Squamous cell carcinoma antigen recognized by T-cells 3 , squamous cell carcinoma antigen recognized by T-cells 3-like , earl grey , egy , p110 , squamous cell carcinoma antigen recognized by T-cells 3 , SART-3 , hSART-3 , tat-interacting protein of 110 kDa , mSART-3 , tumor-rejection antigen SART3

GENE ID SPECIES
416890 Gallus gallus
467123 Pan troglodytes
549486 Xenopus (Silurana) tropicalis
705552 Macaca mulatta
100025301 Monodelphis domestica
100066913 Equus caballus
100076409 Ornithorhynchus anatinus
100137683 Xenopus laevis
100171719 Pongo abelii
100354995 Oryctolagus cuniculus
100410722 Callithrix jacchus
100557456 Anolis carolinensis
100585960 Nomascus leucogenys
558581 Danio rerio
9733 Homo sapiens
486319 Canis lupus familiaris
505922 Bos taurus
53890 Mus musculus
100152586 Sus scrofa
304582 Rattus norvegicus
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